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Yumi Kim

· Associate Professor, Department of Biology

Johns Hopkins University · Genetics and Molecular Biology

Active 2008–2025

h-index64
Citations10.8k
Papers24117 last 5y
Funding—

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

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About

Yumi Kim is an assistant professor in the Department of Biology at Johns Hopkins University. Her research focuses on the molecular mechanisms that drive and coordinate meiotic chromosome dynamics. She received her Ph.D. from UCSD and completed her postdoctoral work at UC Berkeley. Her work aims to understand how homolog pairing, synapsis, and crossover recombination are executed and coordinated during meiotic prophase, using biochemical reconstitution, structural biology, cytological, and genetic analysis in the nematode C. elegans. Accurate chromosome segregation during meiosis is essential for the transmission of stable genomes from parent to offspring, and errors in this process can lead to aneuploidy, which is a major cause of miscarriages and birth defects such as Down syndrome. Her lab investigates the molecular mechanisms ensuring faithful chromosome segregation during meiosis.

Research topics

  • Biology
  • Bioinformatics
  • Computational biology
  • Genetics
  • Internal medicine
  • Evolutionary biology
  • Cancer research
  • Medicine

Selected publications

  • Association of <i>BRAF</i> Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer

    JAMA Surgery · 2018-05-17 · 203 citations

    articleOpen access

    Importance: BRAF mutations are reportedly associated with aggressive tumor biology. However, in contrast with primary colorectal cancer, the association of V600E and non-V600E BRAF mutations with survival and recurrence after resection of colorectal liver metastases (CRLM) has not been well studied. Objective: To investigate the prognostic association of BRAF mutations with survival and recurrence independently and compared with other prognostic determinants, such as KRAS mutations. Design, Sett…

    PublisherOA PDFDOI

  • Sorafenib as an adjuvant therapy for resectable hepatocellular carcinoma: A single center experience.

    PubMed · 2017-06-08 · 7 citations

    article

    PURPOSE: Resectable hepatocellular carcinoma (HCC) is currently treated with surgical resection without any adjuvant therapy. We sought to assess the value of sorafenib as an adjuvant treatment in that clinical setting. METHODS: Of a total of 30 patients, 16 underwent curative- intent liver resection for HCC and subsequently received adjuvant sorafenib, while 14 underwent surgery alone. Clinicopathological characteristics were analyzed and the impact of adjuvant sorafenib on overall survival (OS…

    Publisher

Frequent coauthors

  • Gaya Spolverato

    Quanta Computer (China)

    211 shared

  • Timothy M. Pawlik

    192 shared

  • Aslam Ejaz

    The Ohio State University Wexner Medical Center

    188 shared

  • Timothy M. Pawlik

    The Ohio State University Wexner Medical Center

    148 shared

  • Georgios Antonios Margonis

    Memorial Sloan Kettering Cancer Center

    124 shared

  • Neda Amini

    97 shared

  • George A. Poultsides

    Stanford University

    87 shared

  • Faiz Gani

    86 shared

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