About

Dr. Wayne D. Hsueh was recruited to Rutgers New Jersey Medical School to provide specialized care in all aspects of Rhinology, Sinus, and Endoscopic Skull Base Surgery. His specialized training distinguishes him from other surgeons, with extensive experience in medical conditions such as chronic sinusitis, nasal polyps, allergy, aspirin-exacerbated respiratory disease, and nose bleeds. Surgically, Dr. Hsueh is recognized as a leader and innovator in functional and advanced endoscopic sinus surgery, septal surgery, inferior turbinate resection, nasal cavity and sinus cancer, balloon sinuplasty, nasal valve surgery, rhinoplasty, CSF leaks, and minimally invasive sinus and skull base surgery. He has published extensively on these topics, including state-of-the-art reviews and multiple book chapters, and currently serves as an associate editor of the nationally peer-reviewed journal, the Annals of Otology, Rhinology & Laryngology. Dr. Hsueh's training, combined with his personal dedication, enables him to customize his surgical and medical management skills to meet the needs of his patients. He emphasizes a patient-centered approach with a focus on patient education, active dialogue, and shared decision-making throughout the treatment process.

Research topics

• Surgery
• Medicine
• Internal medicine
• Pathology
• Anesthesia

Selected publications

• Exploring the Predictive Value of National Residency Matching Program (NRMP) Rank in Residency Outcomes

  Annals of Otology Rhinology & Laryngology · 2026-04-06

  articleSenior author

  PURPOSE: To examine the relationship between the National Residency Matching Program (NRMP) rank list position and otolaryngology residency performance. METHODS: Five consecutive graduating classes at a single institution's otolaryngology residency training program (2021-2025) were evaluated (n = 18) using their complete 5-year data. Correlation coefficients were calculated to assess the relationship between NRMP rank and in-service exam scores, research productivity, total case logs, milestone evaluations, selection as Administrative Chief Resident, receipt of teaching awards, and post residency position. Milestone evaluations were based on faculty ratings across all 7 core competencies on a 1- to 7-point scale, with an average score calculated for each resident. Spearman's rho was used to evaluate correlations between NRMP rank and both in-service scores and milestone evaluations. Chi-square tests were conducted to assess associations between NRMP rank and categorical outcomes, including selection as Administrative Chief Resident, receipt of the teaching award, and post residency position. RESULTS: = .020). However, no significant correlations between NRMP rank and in-service exam scores, research productivity, total case logs, selection as Administrative Chief Resident, receipt of the teaching award, or post residency position were found. CONCLUSION: Our results suggest that better-ranked residents receive higher milestone evaluation scores. However, NRMP rank alone may not reliably predict performance on in-service exam scores, chief resident selection, receipt of teaching awards, or position after residency training.

  PublisherDOI

• Sinonasal Cholesteatoma Presenting Within the Maxillary Sinus: A Case Report

  Case Reports in Otolaryngology · 2026-01-01

  articleOpen accessSenior author

  Objectives: Epidermal inclusion cysts are a common type of benign cutaneous cyst. When located in the mastoid cavity, they are more commonly known as cholesteatomas. However, it is extremely rare to be present within the paranasal sinuses, with 20 known cases involving the maxillary sinus. This is a case presentation of an epidermal inclusion cyst of the maxillary sinus, describing its clinical presentation, identifying pathological correlations, and highlighting the importance of early recognition and management. Study Design: A case report. Methods: A retrospective review of the medical records and pathology findings was performed. Results: A previously healthy 20-year-old male presented with several months of bilateral nasal obstruction refractory to medical therapy. Nasal endoscopy demonstrated a deviated septum and edema of the left middle meatus. Noncontrast computed tomography demonstrated opacification of the left maxillary sinus with bony expansion. Of note, there was the appearance of an ectopic tooth within the posterior aspect of the maxillary sinus. Surgical management included septoplasty and left endoscopic maxillary mega-antrostomy. Histopathologic examination of the left maxillary sinus contents was diagnostic of an epidermal inclusion cyst. There was improvement of symptoms and no recurrence or residual cyst during postoperative follow-up at 6 months. Conclusion: This case underscores the need to consider the extremely rare entity of an epidermal inclusion cyst within the differential diagnosis for chronic sinusitis and the need for careful review of imaging for surgical planning. Awareness of this presentation will facilitate accurate diagnosis and appropriate management of this rare disease.

  PublisherDOI

• <scp>RADA</scp> ‐16 Reduces Postoperative Epistaxis After Inferior Turbinate Submucosal Resection

  The Laryngoscope · 2025-05-19 · 3 citations

  articleOpen accessSenior author

  OBJECTIVES: RADA-16 is a self-assembling peptide matrix with the ability to form a hydrogel structure, showing promise for improved wound healing and hemostasis. Our objective was to understand the utility of RADA-16 on postoperative bleeding rates following inferior turbinate submucosal resection (ITR) surgery. STUDY DESIGN: Retrospective study. METHODS: Electronic health records of patients who underwent ITR surgery with a single surgeon from January 2020 to March 2024 were reviewed. Univariate and multivariate analyses were performed to determine differences in postoperative epistaxis rates between RADA-16 and non-RADA-16 cohorts. Further analysis was performed to compare healthcare-associated costs. RESULTS: Our analysis included 985 patients who underwent ITR, of whom 571 received RADA-16 and 414 did not. Overall, 1.11% of patients experienced postoperative bleeding, 0.35% in the RADA-16 cohort and 2.17% in the non-RADA-16 cohort. Patients receiving RADA-16 had a significantly lower risk of postoperative hemorrhage (OR 0.17, 95% CI 0.036-0.808, p = 0.026). Comparison of the two cohorts showed no significant difference in the prevalence of additional nasal surgery or bleeding disorders. The non-RADA-16 group was more likely to be on anticoagulation treatment (p < 0.001); however, no relationship between anticoagulant usage and bleeding episodes was observed. After cost-effectiveness analysis, we found the bleeding cost per patient was $379.74 for the RADA-16 group and $436.21 for the non-RADA-16 group (p = 0.36). CONCLUSIONS: RADA-16 is believed to improve wound healing and hemostasis. In our study, we found that patients receiving RADA-16 are less likely to experience epistaxis following ITR surgery.

  PublisherOA PDFDOI

• Leveraging Large Language Models to Enhance Patient Educational Resources in Rhinology

  Annals of Otology Rhinology & Laryngology · 2025-05-28 · 3 citations

  articleSenior author

  BACKGROUND: To compare the readability of patient education materials (PEMs) on rhinologic conditions and procedures from the American Rhinologic Society (ARS) with those generated by large language models (LLMs). METHODS: Forty-one PEMs from the ARS were retrieved. Readability was assessed through the Flesch Kincaid Reading Ease (FKRE) and Flesch Kincaid Grade Level (FKGL), in which higher FKRE and lower FKGL scores indicate better readability. Three LLMs-ChatGPT 4.o, Google Gemini, and Microsoft Copilot-were then used to translate each ARS PEM to the recommended sixth-grade reading level. Readability scores were calculated and compared for each translated PEM. RESULTS: < .0001). Among the AI platforms, Gemini was the most easily readable, reaching a mean FKGL of 7.5 and FKRE of 65.5. CONCLUSION: LLMs improved the readability of PEMs, potentially enhancing accessibility to medical information for diverse populations. Despite these findings, healthcare providers and patients should cautiously appraise LLM-generated content, particularly for rhinology conditions and procedures. LEVEL OF EVIDENCE: N/A.

  PublisherDOI

• Unilateral Vocal Cord Paresis Caused by Diffuse Idiopathic Skeletal Hyperostosis: Case Report and Literature Review

  Journal of Otorhinolaryngology Hearing and Balance Medicine · 2025-11-06

  articleOpen access

  Background/Objectives: Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by calcification and ossification of ligaments and tendons, primarily affecting the spine. While often asymptomatic, DISH in the cervical spine can cause dysphagia and, more rarely, vocal cord paralysis due to compression of the recurrent laryngeal nerve at the cricothyroid joint. Here, we report cases of unilateral vocal fold paresis in two patients with DISH. Case Presentation: Our first case is an 80-year-old male presented with two months of dysphonia. Strobovideolaryngoscopy found left vocal fold paresis with glottic insufficiency. Computed Tomography (CT) imaging showed DISH with large anteriorly projecting osteophytes in the cervical spine causing rightward deviation of the laryngeal structures and compressing the cricothyroid joint. Second, a 30-year-old female with Turner Syndrome and subglottic stenosis who developed progressively worsening dysphonia over 6 months, characterized by diminished voice projection and clarity. Strobovideolaryngoscopy revealed a mild-to-moderate right vocal fold paresis. CT of the neck demonstrated multiple right-sided osteophytes projecting into the right tracheoesophageal groove, along the course of the right recurrent laryngeal nerve, in the absence of significant disc degeneration. Discussion and Conclusions: On our review of the literature, no other similar instances of unilateral vocal fold paresis were found. We present these cases to emphasize the need for early recognition and treatment to prevent symptom progression of DISH.

  PublisherDOI

• Evaluation of Large Language Models' Concordance With Guidelines on Olfaction

  Laryngoscope Investigative Otolaryngology · 2025-03-22

  articleOpen access

  ABSTRACT Objective To assess the concordance of artificial intelligence (AI)‐generated information with the 2022 International Consensus Statement on Allergy and Rhinology: Olfaction (ICAR‐O). Methods Forty‐two guidelines were extracted from the ICAR‐O. Each guideline was converted into a question, which was presented to ChatGPT version 4.o and Google Gemini. Concordance was deemed an agreement between the AI response and the clinical recommendation. Credibility was granted if the AI platform provided a credible resource. Accuracy was graded on a Likert scale (0: entirely inaccurate information, 1: mix of accurate and inaccurate information, 2: entirely accurate information). Statistical analysis was performed. Results A total of 84 responses were generated. The mean accuracy of the ChatGPT and Gemini responses was 1.85 and 1.48 out of 2, respectively, indicating that the responses contained a mix of accurate and inaccurate information. ChatGPT responses were significantly more accurate than Gemini responses ( p = 0.001). Of the ChatGPT responses, 78.57% ( N = 33) were concordant with the ICAR‐O guidelines and 100% ( N = 42) cited a credible resource. Of the Gemini responses, 66.67% ( N = 28) were concordant and 97.62% ( N = 41) cited a credible resource. There were no significant differences in concordance ( p = 0.22) or credibility ( p = 0.31) between the AI platforms. Conclusion ChatGPT provided more accurate information than Gemini on olfaction. However, overall, both platforms did not consistently align with clinical guidelines. AI platforms require further evaluation before clinical implementation or use as educational adjuncts. Level of Evidence N/A.

  PublisherOA PDFDOI

• In Response to <i> <scp>RADA</scp> ‐16 Reduces Postoperative Epistaxis After Inferior Turbinate Submucosal Resection </i>

  The Laryngoscope · 2025-07-09

  letterOpen accessSenior author
  PublisherOA PDFDOI

• Endoscopic Endonasal Versus Transcranial Approaches to Craniopharyngioma Resection: A Retrospective Series of 38 Cases

  Journal of Neurological Surgery Part B Skull Base · 2024-02-01

  article

  Introduction: Extended Endoscopic Endonasal approaches have become increasingly used for resection of midline craniopharyngiomas. Continued reporting of surgical outcomes is needed to support surgeons' decision making in approach selection, evaluate advantages of each surgical approach, and monitor progression along the learning curve for endonasal approaches to craniopharyngioma. The author presents 38 cases in which craniopharyngioma resections were performed to elaborate on the technical nuances and evaluate surgical outcomes. Furthermore, several systems have been proposed for classification of craniopharyngiomas by location within the anterior skull base, but consensus has not been reached as to which classification is most useful to aid in approach selection.

  PublisherDOI

• Tailored Personalized Strategies and Outcomes with Graduated Multi-angle, Multi-corridor Endoscopic Removal of Juvenile Nasopharyngeal Angiofibromas

  Journal of Neurological Surgery Part B Skull Base · 2024-02-01

  article
  PublisherDOI

• Search for medical information for chronic rhinosinusitis through an artificial intelligence ChatBot

  Laryngoscope Investigative Otolaryngology · 2024-09-09 · 6 citations

  articleOpen access

  Abstract Objectives Artificial intelligence is evolving and significantly impacting health care, promising to transform access to medical information. With the rise of medical misinformation and frequent internet searches for health‐related advice, there is a growing demand for reliable patient information. This study assesses the effectiveness of ChatGPT in providing information and treatment options for chronic rhinosinusitis (CRS). Methods Six inputs were entered into ChatGPT regarding the definition, prevalence, causes, symptoms, treatment options, and postoperative complications of CRS. International Consensus Statement on Allergy and Rhinology guidelines for Rhinosinusitis was the gold standard for evaluating the answers. The inputs were categorized into three categories and Flesch–Kincaid readability, ANOVA and trend analysis tests were used to assess them. Results Although some discrepancies were found regarding CRS, ChatGPT's answers were largely in line with existing literature. Mean Flesch Reading Ease, Flesch–Kincaid Grade Level and passive voice percentage were (40.7%, 12.15%, 22.5%) for basic information and prevalence category, (47.5%, 11.2%, 11.1%) for causes and symptoms category, (33.05%, 13.05%, 22.25%) for treatment and complications, and (40.42%, 12.13%, 18.62%) across all categories. ANOVA indicated no statistically significant differences in readability across the categories ( p ‐values: Flesch Reading Ease = 0.385, Flesch–Kincaid Grade Level = 0.555, Passive Sentences = 0.601). Trend analysis revealed readability varied slightly, with a general increase in complexity. Conclusion ChatGPT is a developing tool potentially useful for patients and medical professionals to access medical information. However, caution is advised as its answers may not be fully accurate compared to clinical guidelines or suitable for patients with varying educational backgrounds. Level of evidence: 4.

  PublisherOA PDFDOI

Frequent coauthors

• Jean Anderson Eloy

  Neurological Surgery

  293 shared

• Soly Baredes

  Rutgers, The State University of New Jersey

  82 shared

• Gregory L. Barinsky

  Rutgers New Jersey Medical School

  60 shared

• Jordon G. Grube

  Albany Medical Center Hospital

  58 shared

• Christina H. Fang

  Montefiore Medical Center

  52 shared

• James K. Liu

  Rutgers, The State University of New Jersey

  50 shared

• Peter F. Svider

  35 shared

• James K. Liu

  Rutgers New Jersey Medical School

  30 shared

Education

• M.D.

  Northwestern University, Feinberg School of Medicine

  2012

• B.A.

  Northwestern University

  2008