Todd Bauer
· Professor of SurgeryUniversity of Virginia · Molecular Physiology and Biological Physics
Active 1998–2026
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About
Todd Bauer is the Stephen H. Watts Professor of Surgery and serves as the Chief of the Division of Surgical Oncology. His research focuses on cancer biology, specifically on developing novel therapies for pancreatic and colorectal cancers. His laboratory is dedicated to understanding cancer metastasis, chemotherapy resistance, and the genetic and epigenetic regulation of cancer. Bauer's work aims to advance treatment options for these cancers through innovative research in experimental pathology and cancer biology.
Research topics
- Surgery
- Internal medicine
- Medicine
- Computational biology
- Biology
- Genetics
- Cancer research
- General surgery
- Gastroenterology
Selected publications
Very Early Recurrence After Liver Resection for Intrahepatic Cholangiocarcinoma
JAMA Surgery · 2020 · 242 citations
Importance: Although surgery offers the best chance of a potential cure for patients with localized, resectable intrahepatic cholangiocarcinoma (ICC), prognosis of patients remains dismal largely because of a high incidence of recurrence. Objective: To predict very early recurrence (VER) (ie, recurrence within 6 months after surgery) following resection for ICC in the pre- and postoperative setting. Design, Setting, and Participants: Patients who underwent curative-intent resection for ICC betwe…
Proceedings of the National Academy of Sciences · 2020 · 109 citations
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most challenging cancers to treat. Due to the asymptomatic nature of the disease and lack of curative treatment modalities, the 5-y survival rate of PDAC patients is one of the lowest of any cancer type. The recurrent genetic alterations in PDAC are yet to be targeted. Therefore, identification of effective drug combinations is desperately needed. Here, we performed an in vivo CRISPR screen in an orthotopic patient-derived xenograft (PDX…
Annals of Surgical Oncology · 2020 · 96 citations
British journal of surgery · 2025-03-28 · 8 citations
articleOpen accessBACKGROUND: Liver resection for multifocal intrahepatic cholangiocarcinoma (ICC) remains controversial due to a poor prognosis, driven by aggressive tumour biology. The aim of this study was to stratify multifocal ICC patients to identify those who are likely to benefit from resection. METHODS: Patients who underwent upfront curative-intent hepatectomy for ICC were identified from an international multi-institutional database. Among patients with multifocal tumours, overall survival (OS) was ana…
ACS Sensors · 2025-06-06 · 7 citations
articleOpen accessMicrofluidic cell separation by dielectrophoresis, based on biophysical and electrical physiology metrics, is often optimized using on-chip fluorescence microscopy or off-chip flow cytometry of the separated fractions. However, these techniques require fluorescent reporters or stained samples that operate as end point assays, preventing the separated cell fractions from being utilized for longitudinal or transplantation studies. Single-cell impedance cytometry has a small footprint for facile in…
Recent grants
NIH · $152k · 2011
Frequent coauthors
- 488 shared
Shishir K. Maithel
Emory University
- 482 shared
George A. Poultsides
Stanford University
- 482 shared
Carlo Pulitanò
University of Sydney
- 470 shared
Feng Shen
Eastern Hepatobiliary Surgery Hospital
- 450 shared
Matthew J. Weiss
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
- 443 shared
Guillaume Martel
Ottawa Hospital
- 437 shared
Luca Aldrighetti
Istituti di Ricovero e Cura a Carattere Scientifico
- 437 shared
Hugo P. Marques
Education
- 2005
Fellowship in Surgical Oncology, Department of Surgical Oncology
University of Texas MD Anderson Cancer Center
- 2002
General Surgery Residency, Department of Surgery
Hospital of the University of Pennsylvania
- 1995
M.D., School of Medicine
University of Pennsylvania
- 1991
B.S. in Economics, Wharton School of Business
University of Pennsylvania
- 1991
B.A., College of Arts and Sciences
University of Pennsylvania
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