Sunil Wadhwa

About

Sunil Wadhwa, DDS, is a Professor of Orthodontics in the Department of Dental Medicine at Columbia University Irving Medical Center. He serves as the Chair of the Section of Growth and Development and is the Director of the Division of Orthodontics. His academic appointment is within the Leuman M. Waugh D.D.S. professorship. Dr. Wadhwa's research focuses on the biology of tooth movement and the sex dimorphism of temporomandibular joint disorders. His work involves understanding the biological mechanisms underlying orthodontic treatment and temporomandibular joint conditions, contributing to advancements in orthodontic science and patient care.

Research topics

• Medicine
• Immunology
• Internal medicine
• Biology
• Bioinformatics
• Dentistry
• Surgery

Selected publications

• Oral and Gut Microbial Diversity and Immune Regulation in Patients with HIV on Antiretroviral Therapy

  mSphere · 2020 · 58 citations

  A feedback loop between dysbiotic gut microbiota, increased translocation of microbial products such as lipopolysaccharide, and inflammation has been hypothesized to cause immune system dysfunction in early HIV infection. However, despite evidence of a chronic inflammatory phenotype in patients on antiretroviral therapy (ART), the role of oral microbiota in systemic immune activation and the relationship between oral and gut bacterial and fungal diversity have not been explored. Our study sugges…

  PublisherOA PDFDOI

• Orthodontic educational landscape in the contemporary context: Insights from educators

  Seminars in Orthodontics · 2024-05-19 · 14 citations

  reviewOpen access
  PublisherOA PDFDOI

• The Role of Oral Health in the Acquisition and Severity of SARS-CoV-2: A Retrospective Chart Review

  The Saudi Dental Journal · 2022 · 10 citations

  1st authorCorresponding

  Objective: entry. However, the role of oral health in the acquisition and severity of COVID-19 is not known. Design: A retrospective analysis was performed using electronic health record data from a large urban academic medical center between 12/1/2019 and 8/24/2020. A total of 387 COVID-19 positive cases were identified and matched 1:1 by age, sex, and race to 387 controls without COVID-19 diagnoses. Demographics, number of missing teeth and alveolar crestal height were determined from radiogra…

  PublisherDOI

• Detection of SARS-CoV-2 IgG antibodies and inflammatory cytokines in saliva-a pilot study

  Journal of Oral Biology and Craniofacial Research · 2023 · 9 citations

  1st authorCorresponding

  Objective: The pandemic caused by SARS-CoV-2 virus continues to have a profound effect worldwide. However, COVID-19 induced oral facial manifestations have not been fully described. We conducted a prospective study to demonstrate feasibility of anti-SARS-CoV-2 IgG and inflammatory cytokine detection in saliva. Our primary objective was to determine whether COVID-19 PCR positive patients with xerostomia or loss of taste had altered serum or saliva cytokine levels compared to COVID-19 PCR positive…

  PublisherDOI

• Evaluation by dental professionals of an artificial intelligence-based application to measure alveolar bone loss

  BMC Oral Health · 2025-03-01 · 7 citations

  articleOpen accessSenior author

  BACKGROUND: Several commercial programs incorporate artificial intelligence in diagnosis, but very few dental professionals have been surveyed regarding its acceptability and usability. Furthermore, few have explored how these advances might be incorporated into routine practice. METHODS: Our team developed and implemented a deep learning (DL) model employing semantic segmentation neural networks and object detection networks to precisely identify alveolar bone crestal levels (ABCLs) and cemento…

  PublisherOA PDFDOI

Recent grants

• Estrogen Receptor Beta Regulation of Mandibular Condylar Growth

  NIH · $1.5M · 2010–2014

• Multidisciplinary Training in TMJ Disorders/Pain: Integrating Basic, Translation

  NIH · $1.2M · 2013–2018

• Oral immune activation and alveolar bone loss in HIV-infected postmenopausal women

  NIH · $2.3M · 2017–2024

Frequent coauthors

• Marian F. Young

  25 shared

• Michael T. Yin

  Columbia University

  16 shared

• Tina M. Kilts

  National Institutes of Health

  15 shared

• Žana Kalajzić

  UConn Health

  12 shared

• Mildred C. Embree

  Columbia University

  11 shared

• Achint Utreja

  10 shared

• Flávio Uribe

  University of Connecticut

  10 shared

• Ravindra Nanda

  University of Connecticut

  8 shared