Steven Rasmussen

About

Steven A. Rasmussen, MD, MMS is a Professor of Psychiatry and Human Behavior and serves as the Chair of the Department of Psychiatry and Human Behavior at the Alpert Medical School of Brown University. He is an internationally recognized expert in the course and treatment of obsessive compulsive disorder (OCD). His primary research interests include neurosurgical approaches to intractable OCD and depression, the neurocircuitry of OCD, and the longitudinal course of OCD. Dr. Rasmussen has authored or coauthored over 100 peer-reviewed publications and has been actively involved in studies funded by multiple R01 grants from the NIMH, focusing on understanding the neurobiological underpinnings of OCD and related conditions. He has contributed significantly to bridging campus-based and hospital-based brain science faculty at Brown University, advancing research and clinical care in psychiatric neuroscience.

Research topics

• Psychology
• Medicine
• Radiology
• Neuroscience
• Internal medicine
• Surgery

Selected publications

• Functional disruption in prefrontal-striatal network in obsessive-compulsive disorder

  Psychiatry Research Neuroimaging · 2020 · 35 citations

  DOI

• Magnetic Resonance Imaging-Guided Laser Thermal Ventral Capsulotomy for Intractable Obsessive-Compulsive Disorder

  Neurosurgery · 2021 · 31 citations

  BACKGROUND: Obsessive-compulsive disorder (OCD) is a disabling condition characterized by intrusive thoughts and repetitive behaviors. A subset of individuals have severe, treatment-resistant illness and are nonresponsive to medication or behavioral therapies. Without response to conventional therapeutic options, surgical intervention becomes an appropriate consideration. OBJECTIVE: To report clinical outcomes and the safety profile of bilateral ventral anterior capsulotomy for OCD using magneti…

  DOI

• Gamma knife capsulotomy for intractable OCD: Neuroimage analysis of lesion size, location, and clinical response

  Translational Psychiatry · 2023-04-26 · 19 citations

  articleOpen access

  Obsessive-compulsive disorder (OCD) affects 2-3% of the population. One-third of patients are poorly responsive to conventional therapies, and for a subgroup, gamma knife capsulotomy (GKC) is an option. We examined lesion characteristics in patients previously treated with GKC through well-established programs in Providence, RI (Butler Hospital/Rhode Island Hospital/Alpert Medical School of Brown University) and São Paulo, Brazil (University of São Paolo). Lesions were traced on T1 images from 2…

  PublisherOA PDFDOI

• Directionality of change in obsessive compulsive disorder and depression over six years of prospective follow-up

  Journal of Psychiatric Research · 2022-11-29 · 11 citations

  articleOpen access
  PublisherOA PDFDOI

• Spatial normalization discrepancies between native and MNI152 brain template scans in gamma ventral capsulotomy patients

  Psychiatry Research Neuroimaging · 2023-01-17 · 10 citations

  articleOpen access
  PublisherOA PDFDOI

Recent grants

• Longitudinal Follow-Up Study of Obsessive Compulsive Disorder

  NIH · $6.3M · 2001–2017

• Physiology and information processing of the OCD circuit

  NIH · $51.3M · 2015–2027

• NIH Grant P50MH086400

  NIH · $20.5M · 2015

Frequent coauthors

• Benjamin D. Greenberg

  Providence VA Medical Center

  333 shared

• Jonathan A. Eisen

  265 shared

• Maria C. Mancebo

  Providence College

  195 shared

• Nicole McLaughlin

  Allen Institute for Brain Science

  157 shared

• Lawrence H. Price

  106 shared

• Katharine A. Phillips

  104 shared

• Sarah L. Garnaat

  Dartmouth College

  96 shared

• Christina L. Boisseau

  92 shared

Education

• Other

  Brown Medical School

  1977

• M.D.

  Brown Medical School

  1977

Similar researchers at Brown University

• Karen Furieh-148
• Rena Wingh-146