Stephen Wong

About

Stephen Wong is an experienced computer scientist, physicist, and educator specializing in object-oriented programming, software engineering, and computer science pedagogy. His current research includes the use of design patterns in redesigning traditional algorithms, serious gaming systems, cloud-based enterprise information management systems, large-scale high-fidelity simulation systems, and technologies for massive open online courses. He holds a PhD in Physics from MIT, obtained in 1989, and a BA in Physics with minors in Digital Electronics and Physical Chemistry from Swarthmore College, earned in 1981.

Research topics

• Genetics
• Biology
• Cancer research
• Computational biology
• Mathematics
• Evolutionary biology
• Combinatorics

Selected publications

• Supplementary Table I from Tumor NOS2 and COX2 Spatial Juxtaposition with CD8<sup>+</sup> T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER<sup>−</sup> Breast Cancer

  2026-03-16

  articleOpen access

  <p>Supplementary Table I summarizes pathological features of tumor immune microenvironment where NOS2+ inflamed regions are significantly higher in tumors from Deceased patients.</p>

  PublisherDOI

• Supplementary Figure 2 from Tumor NOS2 and COX2 Spatial Juxtaposition with CD8<sup>+</sup> T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER<sup>−</sup> Breast Cancer

  2026-03-16

  articleOpen access

  <p>Tumor analysis of NOS2 and COX2.</p>

  PublisherDOI

• Supplementary Figure 5 from Tumor NOS2 and COX2 Spatial Juxtaposition with CD8<sup>+</sup> T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER<sup>−</sup> Breast Cancer

  2026-03-16

  articleOpen access

  <p>Spatial dot plot of CD8+/-NOS2+/-COX2+/- phenotypes in tumor from deceased patient.</p>

  PublisherDOI

• Supplementary Figure 3 from Tumor NOS2 and COX2 Spatial Juxtaposition with CD8<sup>+</sup> T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER<sup>−</sup> Breast Cancer

  2026-03-16

  articleOpen access

  <p>Immune and tumor quantification</p>

  PublisherDOI

• Supplementary Table II from Tumor NOS2 and COX2 Spatial Juxtaposition with CD8<sup>+</sup> T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER<sup>−</sup> Breast Cancer

  2026-03-16

  articleOpen access

  <p>Supplementary Table II summarizes �8+ T cells in designated regions of the tumors.</p>

  PublisherDOI

Recent grants

• Systematic Alzheimer's disease drug repositioning (SMART) based on bioinformatics-guided phenotype screening and image-omics

  NIH · $3.5M · 2018–2024

• NIH Grant R01LM008696

  NIH · $1.0M · 2009

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  NIH · $2.6M · 2020–2025

Frequent coauthors

• Xiaobo Zhou

  369 shared

• Hong Zhao

  Children's Hospital of Zhejiang University

  323 shared

• Kelvin Wong

  Houston Methodist

  297 shared

• Jianting Sheng

  Weill Cornell Medicine

  252 shared

• Fuhai Li

  Washington University in St. Louis

  239 shared

• Zheng Yin

  Houston Methodist

  225 shared

• Zhong Xue

  200 shared

• Kemi Cui

  Albany Medical Center Hospital

  180 shared

Similar researchers at Rice University

• Moshe Y. Vardih-105
• Richard G. Baraniukh-97
• Lydia E. Kavrakih-71