Stephanie J. Smith

About

Stephanie J. Smith is a Professor of History at The Ohio State University, specializing in Latin American history with a focus on Mexico and its cultural and political developments. She joined the department in 2003 after earning her Ph.D. in History from the State University of New York at Stony Brook in 2002. Her research explores the complex relationships between radical artists, including Diego Rivera, David Alfaro Siqueiros, and Frida Kahlo, and Mexico's postrevolutionary state, as evidenced by her book The Power and Politics of Art in Postrevolutionary Mexico. Her earlier work, Gender and the Mexican Revolution: Yucatán Women and the Realities of Patriarchy, examines women's involvement during the Mexican Revolution. Currently, she is working on a new book titled Through Frida’s Eyes: Frida Kahlo and the Creative Women Who Radicalized Mexico. Professor Smith has received numerous research grants, including a Fulbright Dissertation Research Abroad Grant and an American Association of University Women Dissertation Fellowship. She has presented her work at various conferences and institutions, and has been recognized for her teaching excellence with awards such as the Paul Brown Excellence in Teaching Award. She teaches courses on the History of Mexico, Latin American revolutions and social movements, and Latin American history through film, among others. Her media appearances include being featured in the BBC documentary series Becoming Frida Kahlo, which examines the…

Research topics

• Internal medicine
• Pharmacology
• Bioinformatics
• Cancer research
• Medicine
• Biology

Selected publications

• Variant Interpretation for Dilated Cardiomyopathy

  Circulation Genomic and Precision Medicine · 2020-04-01 · 116 citations

  articleOpen access

  Background: The hypothesis of the Dilated Cardiomyopathy Precision Medicine Study is that most dilated cardiomyopathy has a genetic basis. The study returns results to probands and, when indicated, to relatives. While both the American College of Medical Genetics and Genomics/Association for Molecular Pathology and ClinGen’s MYH7 -cardiomyopathy specifications provide relevant guidance for variant interpretation, further gene- and disease-specific considerations were required for dilated cardiom…

  PublisherOA PDFDOI

• Targeting OCT3 attenuates doxorubicin-induced cardiac injury

  Proceedings of the National Academy of Sciences · 2021 · 65 citations

  Doxorubicin is a commonly used anticancer agent that can cause debilitating and irreversible cardiac injury. The initiating mechanisms contributing to this side effect remain unknown, and current preventative strategies offer only modest protection. Using stem-cell-derived cardiomyocytes from patients receiving doxorubicin, we probed the transcriptomic landscape of solute carriers and identified organic cation transporter 3 (OCT3) (SLC22A3) as a critical transporter regulating the cardiac accumu…

  DOI

• Early toxicity and clinical outcomes after chimeric antigen receptor T-cell (CAR-T) therapy for lymphoma

  Journal for ImmunoTherapy of Cancer · 2021-08-01 · 61 citations

  articleOpen access

  BACKGROUND: Chimeric antigen receptor T-cell (CAR-T) infusion is associated with early toxicity. Yet, whether early toxicity development holds ramifications for long-term outcomes is unknown. METHODS: From a large cohort of consecutive adult patients treated with CAR-T therapies for relapsed or refractory lymphomas from 2016 to 2019, we assessed progression-free survival (PFS), by toxicity development (cytokine release syndrome (CRS), neurotoxicity, or cardiotoxicity]. We also assessed the relat…

  PublisherOA PDFDOI

• Human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) for modeling cardiac arrhythmias: strengths, challenges and potential solutions

  Frontiers in Physiology · 2024-09-12 · 26 citations

  reviewOpen accessSenior author

  Ion channels and cytoskeletal proteins in the cardiac dyad play a critical role in maintaining excitation-contraction (E-C) coupling and provide cardiac homeostasis. Functional changes in these dyad proteins, whether induced by genetic, epigenetic, metabolic, therapeutic, or environmental factors, can disrupt normal cardiac electrophysiology, leading to abnormal E-C coupling and arrhythmias. Animal models and heterologous cell cultures provide platforms to elucidate the pathogenesis of arrhythmi…

  PublisherOA PDFDOI

• Atrial fibrillation in cancer, anticancer therapies, and underlying mechanisms

  Journal of Molecular and Cellular Cardiology · 2024-06-17 · 7 citations

  reviewOpen accessSenior authorCorresponding
  PublisherOA PDFDOI

Recent grants

• Defining Novel Cardiovascular Mechanisms For TKI Induced Excitability

  NIH · $1.6M · 2022–2027

• Defining New Pathways in Heart Failure and Arrhythmia

  NIH · $150k · 2017–2021

• Translational Candidate-Gene Studies of Simvastatin-Induced Myopathy in African Americans

  NIH · $1.9M · 2017–2022

Frequent coauthors

• Philip F. Binkley

  The Ohio State University Wexner Medical Center

  167 shared

• Peter J. Mohler

  The Ohio State University

  142 shared

• Thomas J. Hund

  The Ohio State University

  128 shared

• Michael Makara

  116 shared

• Jerry Curran

  113 shared

• Ahmet Kılıç

  Johns Hopkins Hospital

  112 shared

• Paul M.L. Janssen

  The Ohio State University

  111 shared

• Cynthia A. Carnes

  The Ohio State University

  110 shared

Education

• General Cardiology and Transplant Fellowship, Cardiology

  Ohio State University

  2014

• Residency, Internal Medicine

  Washington University in Saint Louis

  2009

• MD

  Temple University

  2006

• BS, Biology

  Truman State University

  1999

Awards & honors

• American Association of University Women Dissertation Fellow…
• Fulbright Dissertation Research Abroad Grant to Mexico (Fulb…
• Paul Brown Excellence in Teaching Award from the Ohio State…
• Clio Award, Phi Alpha Theta (2009)

Similar researchers at Ohio State University

• Jim Harrish-79
• Robert J. McMahonh-53
• Trevor Johnsonh-21