Solomon, Adam

About

The page provides information about the New York University Stern Center for Research Computing (SCRC), which is devoted to providing world-class computational facilities and services to researchers at the Stern School of Business. These services include a moderately sized Slurm HPC cluster, Cloud Computing (Virtual Machines), data acquisition and storage, research software, and access to WRDS (Wharton Research Data System). The center offers a comprehensive suite of software services designed to facilitate advanced computational research and data analysis, as well as access to datasets from diverse disciplines through collaborations with data repositories, platforms, and academic institutions. Additionally, the center supports faculty and researchers' projects with a wide range of computing services and resources, including high-speed, robust, and scalable storage systems to meet diverse computational and storage needs.

Research topics

• Immunology
• Biology
• Cancer research
• Genetics
• Cell biology
• Biochemistry
• Bioinformatics
• Chemistry
• Microbiology

Selected publications

• PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer

  Nature Immunology · 2020 · 393 citations

  PublisherDOI

• γδ T Cells Promote Steatohepatitis by Orchestrating Innate and Adaptive Immune Programming

  Hepatology · 2019-09-17 · 83 citations

  article

  Background and Aims The recruitment and activation of inflammatory cells in the liver delineates the transition from hepatic steatosis to steatohepatitis (SH). Approach and Results We found that in SH, γδT cells are recruited to the liver by C‐C chemokine receptor (CCR) 2, CCR5, and nucleotide‐binding oligomerization domain‐containing protein 2 signaling and are skewed toward an interleukin (IL)‐17A + phenotype in an inducible costimulator (ICOS)/ICOS ligand–dependent manner. γδT cells exhibit a…

  PublisherDOI

• Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma

  Nature Communications · 2019-03-29 · 82 citations

  articleOpen access

  Abstract The drivers and the specification of CD4 + T cell differentiation in the tumor microenvironment and their contributions to tumor immunity or tolerance are incompletely understood. Using models of pancreatic ductal adenocarcinoma (PDA), we show that a distinct subset of tumor-infiltrating dendritic cells (DC) promotes PDA growth by directing a unique T H -program. Specifically, CD11b + CD103 − DC predominate in PDA, express high IL-23 and TGF-β, and induce FoxP3 neg tumor-promoting IL-10…

  PublisherOA PDFDOI

• Intrahepatic microbes govern liver immunity by programming NKT cells

  Journal of Clinical Investigation · 2022 · 70 citations

  The gut microbiome shapes local and systemic immunity. The liver is presumed to be a protected sterile site. As such, a hepatic microbiome has not been examined. Here, we showed a liver microbiome in mice and humans that is distinct from that of the gut and is enriched in Proteobacteria. It undergoes dynamic alterations with age and is influenced by the environment and host physiology. Fecal microbial transfer experiments revealed that the liver microbiome is populated from the gut in a highly s…

  PublisherOA PDFDOI

• Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis

  Oncogene · 2019-02-11 · 45 citations

  article
  PublisherDOI

Frequent coauthors

• Joshua Leinwand

  Kettering University

  13 shared

• Berk Aykut

  Duke University

  13 shared

• George Miller

  13 shared

• Juan Andres Kochen Rossi

  New York University

  11 shared

• Mautin Hundeyin

  11 shared

• Emma Kurz

  11 shared

• Brian Diskin

  11 shared

• Mohammad Saad Farooq

  Ayub Medical College

  10 shared

Similar researchers at New York University

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