Simin Liu
· Chair and Distinguished Professor of the Department of Epidemiology & Biostatistics, Director, Center for Global Cardiometabolic Health & Nutrition, Distinguished Professor of Medicine, UC Irvine School of MedicineUniversity of California, Irvine · Epidemiology & Biostatistics
Active 1957–2026
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About
Simin Liu, MD, ScD, is a Distinguished Professor and Chair of the Department of Epidemiology and Biostatistics at the UC Irvine Wen Public Health School of Population & Public Health. He also serves as the Director of the Center for Global Cardiometabolic Health & Nutrition and is a Distinguished Professor of Medicine at the UC Irvine School of Medicine. Dr. Liu has worked in the global health space for three decades, establishing a wide variety of collaborative research projects in diverse communities worldwide. His research spans from investigating the genetic basis of cardiometabolic diseases to clinical epidemiology, risk modeling, and interventions in diverse populations, developing the G6P framework that integrates data from multiple platforms for causal inference.
Research topics
- Biology
- Genetics
- Medicine
- Evolutionary biology
- Demography
- Computational biology
- Internal medicine
- Bioinformatics
- Endocrinology
- Environmental health
Selected publications
The Lancet · 2020 · 9387 citations
BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. METHODS: GBD 2019 estimat…
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
Nature · 2021 · 2261 citations
. In the first 53,831 TOPMed samples, we detected more than 400 million single-nucleotide and insertion or deletion variants after alignment with the reference genome. Additional previously undescribed variants were detected through assembly of unmapped reads and customized analysis in highly variable loci. Among the more than 400 million detected variants, 97% have frequencies of less than 1% and 46% are singletons that are present in only one individual (53% among unrelated individuals). These…
Global Burden of Cardiovascular Diseases and Risks, 1990-2022
Journal of the American College of Cardiology · 2023 · 1365 citations
The trans-ancestral genomic architecture of glycemic traits
Nature Genetics · 2021 · 877 citations
Inherited causes of clonal haematopoiesis in 97,691 whole genomes
Nature · 2020 · 726 citations
Recent grants
NIH · $695k · 2020–2025
NIH · $8.4M · 2007
NIH · $2.7M · 2012
Frequent coauthors
- 1142 shared
JoAnn E. Manson
Brigham and Women's Hospital
- 450 shared
Charles B. Eaton
Kent Hospital
- 342 shared
Karen L. Margolis
HealthPartners
- 308 shared
Rebecca D. Jackson
The Ohio State University Wexner Medical Center
- 303 shared
Lesley F. Tinker
Fred Hutch Cancer Center
- 294 shared
Yiqing Song
State Key Laboratory of Medicinal Chemical Biology
- 263 shared
Lawrence S. Phillips
- 256 shared
X. Zhang
Ningbo University
Education
- 2002
Ph.D., Environmental Health Sciences
University of California, Los Angeles
- 1998
M.S., Environmental Health Sciences
University of California, Los Angeles
- 1996
B.S., Environmental Health Sciences
University of California, Los Angeles
Awards & honors
- Swedish Fellowship, Karolinska Institute, Stockholm, Sweden…
- Physician Scientist Development Award (K08), National Instit…
- Fellow of the American Heart Association (FAHA) (2004)
- Elected Member, American Society of Clinical Investigation (…
- Elected Member, American Epidemiological Society (AES) (2012…
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