S. Munir Alam

About

S. Munir Alam is a Professor in Medicine and a Professor of Pathology at Duke University. He is a member of the Duke Human Vaccine Institute. His professional roles are based at Duke's Department of Medicine, with a research focus that includes vaccine development and infectious diseases. His work involves contributions to the understanding of immune responses and vaccine strategies, supporting Duke's mission in advancing medical research and education.

Research topics

• Immunology
• Biology
• Virology
• Medicine
• Neuroscience
• Genetics
• Anatomy
• Computational biology
• Molecular biology
• Cell biology

Selected publications

• In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

  Cell · 2021 · 330 citations

  DOI

• Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

  Nature · 2021 · 275 citations

  PublisherOA PDFDOI

• Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

  Cell · 2021 · 90 citations

  DOI

• Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques

  Cell · 2024-01-01 · 55 citations

  articleOpen access
  PublisherOA PDFDOI

• Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans

  Cell · 2024-05-17 · 47 citations

  articleOpen accessCorresponding

  A critical roadblock to HIV vaccine development is the inability to induce B cell lineages of broadly neutralizing antibodies (bnAbs) in humans. In people living with HIV-1, bnAbs take years to develop. The HVTN 133 clinical trial studied a peptide/liposome immunogen targeting B cell lineages of HIV-1 envelope (Env) membrane-proximal external region (MPER) bnAbs (NCT03934541). Here, we report MPER peptide-liposome induction of polyclonal HIV-1 B cell lineages of mature bnAbs and their precursors…

  PublisherOA PDFDOI

Recent grants

• NIH Grant U19AI067854

  NIH · $294.0M · 2013

Frequent coauthors

• Barton F. Haynes

  Duke University

  172 shared

• David C. Montefiori

  Duke University

  132 shared

• Hua‐Xin Liao

  104 shared

• Georgia D. Tomaras

  Duke University

  101 shared

• M. Anthony Moody

  Duke University

  96 shared

• Kevin Wiehe

  Duke University

  87 shared

• Kevin O. Saunders

  Duke University

  83 shared

• Guido Ferrari

  Duke Medical Center

  72 shared

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