Peter Campochiaro
· Professor of OphthalmologyJohns Hopkins University · Neurosciences
Active 1976–2025
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About
Peter Anthony Campochiaro, M.D., is the George S. and Dolores Doré Eccles Professor of Ophthalmology and Neuroscience at The Wilmer Eye Institute, Johns Hopkins University School of Medicine. Born on September 23, 1952, in Cohoes, New York, Dr. Campochiaro completed his B.S. at the University of Notre Dame, graduating magna cum laude and Phi Beta Kappa, followed by his M.D. at Johns Hopkins University School of Medicine. His academic career includes appointments as Assistant, Associate, and full Professor of Ophthalmology at the University of Virginia School of Medicine before joining Johns Hopkins, where he has served as Professor of Ophthalmology and Neuroscience and Director of Vitreoretinal Surgery. Dr. Campochiaro's research focuses on retinal diseases, particularly mechanisms underlying ocular neovascularization, diabetic retinopathy, macular edema, and retinal degenerations such as retinitis pigmentosa. He has contributed extensively to understanding the roles of growth factors like PDGFs and FGFs, oxidative damage, and molecular pathways involved in retinal pathology. His work includes pioneering studies on gene therapy, anti-angiogenic agents, and novel peptide inhibitors for ocular diseases. Dr. Campochiaro has received numerous honors, including the Rosenthal Award from the Macula Society, the Proctor Medal from the Association for Research in Vision and Ophthalmology, and election to the National Academy of Inventors. He has been continuously funded by the NIH…
Research topics
- Medicine
- Ophthalmology
- Internal medicine
- Pharmacology
- Biology
- Endocrinology
- Genetics
- Cancer research
- Pathology
- Composite material
Selected publications
The Lancet · 2020 · 291 citations
Ophthalmology · 2021-09-29 · 175 citations
articleOpen accessPURPOSE: To evaluate the safety and efficacy of the Port Delivery System with ranibizumab (PDS) for the treatment of neovascular age-related macular degeneration (nAMD). DESIGN: Phase 3, open-label, randomized, visual acuity assessor-masked noninferiority and equivalence trial. PARTICIPANTS: Patients with nAMD diagnosed within 9 months of screening previously treated with and responsive to anti-vascular endothelial growth factor therapy. METHODS: Patients were randomized 3:2 to treatment with th…
Ophthalmology · 2024 · 163 citations
PURPOSE: To evaluate 2-year efficacy, durability, and safety of the bispecific antibody faricimab, which inhibits both angiopoietin-2 and VEGF-A. DESIGN: TENAYA (ClinicalTrials.gov identifier, NCT03823287) and LUCERNE (ClinicalTrials.gov identifier, NCT03823300) were identically designed, randomized, double-masked, active comparator-controlled phase 3 noninferiority trials. PARTICIPANTS: Treatment-naive patients with neovascular age-related macular degeneration (nAMD) 50 years of age or older. M…
Faricimab Treat-and-Extend for Diabetic Macular Edema
Ophthalmology · 2023 · 133 citations
PURPOSE: To evaluate the 2-year efficacy, durability, and safety of dual angiopoietin-2 and vascular endothelial growth factor (VEGF) A pathway inhibition with intravitreal faricimab according to a personalized treat-and-extend (T&E)-based regimen with up to every-16-week dosing in the YOSEMITE and RHINE (ClinicalTrials.gov identifiers, NCT03622580 and NCT03622593, respectively) phase 3 trials of diabetic macular edema (DME). DESIGN: Randomized, double-masked, noninferiority phase 3 trials. PART…
Gelling hypotonic polymer solution for extended topical drug delivery to the eye
Nature Biomedical Engineering · 2020 · 122 citations
Recent grants
Suprachoroidal nonviral gene transfer of engineered VEGF antagonists
NIH · $2.4M · 2020–2025
A novel hypotonic gelling eye drop for topical treatment of retinal degenerative diseases
NIH · $1.6M · 2020–2023
NIH · $2.3M · 2019–2028
Frequent coauthors
- 219 shared
Jikui Shen
Johns Hopkins Medicine
- 193 shared
Sean F. Hackett
Nottingham University Hospitals NHS Trust
- 178 shared
Donald J. Zack
Johns Hopkins University
- 159 shared
Sean F. Hackett
Johns Hopkins Medicine
- 117 shared
Stanley A. Vinores
Johns Hopkins University
- 112 shared
Syed Mahmood Shah
Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir
- 95 shared
Yogita Kanan
- 93 shared
Mahmood Khan
Labs
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