Paul S. Weiss
· PhD, Presidential Professor of ChemistryUniversity of California, Los Angeles · Chemistry and Biochemistry
Active 1901–2026
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About
Paul S. Weiss holds a UC Presidential Chair and is a distinguished professor of chemistry & biochemistry, bioengineering, and materials science & engineering at UCLA. His interdisciplinary research group includes chemists, physicists, biologists, materials scientists, mathematicians, bioengineers, electrical and mechanical engineers, computer scientists, clinicians, and physician scientists. They focus on exploring the atomic-scale chemical, physical, optical, mechanical, electronic, thermal, and spin properties of surfaces, interfaces, supramolecular, and biomolecular assemblies, aiming to understand the limits of miniaturization. Weiss develops new techniques to expand the applicability and chemical specificity of scanning probe microscopies, applying these tools to study self- and directed assembly, and molecular and nanoscale devices. His work advances nanofabrication to operate and test functional molecular assemblies, connecting to the chemical and biological worlds in areas such as neuroscience, gene editing, cancer immunotherapy, tissue engineering, cellular agriculture, and the microbiome. He has authored over 500 publications, holds over 40 patents, and has given more than 1000 invited, plenary, keynote, and named lectures. Weiss has served in various leadership roles, including director of the California NanoSystems Institute, and has been involved in startups across biotechnology, food security, energy, entertainment, and healthcare sectors. His numerous awards…
Research topics
- Engineering
- Computer Science
- Nanotechnology
- Materials science
- Electrical engineering
- Political Science
- Business
- Data science
- Risk analysis (engineering)
- Systems engineering
Selected publications
Technology Roadmap for Flexible Sensors
ACS Nano · 2023 · 1225 citations
Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited. To ease and to expedite their deployment, here, we identify bottlenecks hindering the maturation of flexible sensor…
Electrode Degradation in Lithium-Ion Batteries
ACS Nano · 2020 · 801 citations
and graphite) can be achieved. The transition to higher-capacity electrode materials in commercial applications is complicated by several factors. This Review highlights the developments of electrode materials and characterization tools for rechargeable lithium-ion batteries, with a focus on the structural and electrochemical degradation mechanisms that plague these systems.
Wearable aptamer-field-effect transistor sensing system for noninvasive cortisol monitoring
Science Advances · 2022 · 361 citations
FETs. Cortisol levels were determined via molecular recognition by aptamers where binding was transduced to electrical signals on FETs. The physiological relevance of cortisol as a stress biomarker was demonstrated by tracking salivary cortisol levels in participants in a Trier Social Stress Test and establishing correlations between cortisol in diurnal saliva and sweat samples. These correlations motivated the development and on-body validation of an aptamer-FET array–based smartwatch equipped…
ACS Nano · 2021 · 336 citations
Nanotechnology has important roles to play in international efforts in sustainability. We discuss how current and future capabilities in nanotechnology align with and support the United Nations' Sustainable Development Goals. We argue that, as a field, we can accelerate the progress toward these goals both directly through technological solutions and through our special interdisciplinary skills in communication and tackling difficult challenges. We discuss the roles of targeting solutions, techn…
A Chirality-Based Quantum Leap
ACS Nano · 2022 · 189 citations
There is increasing interest in the study of chiral degrees of freedom occurring in matter and in electromagnetic fields. Opportunities in quantum sciences will likely exploit two main areas that are the focus of this Review: (1) recent observations of the chiral-induced spin selectivity (CISS) effect in chiral molecules and engineered nanomaterials and (2) rapidly evolving nanophotonic strategies designed to amplify chiral light-matter interactions. On the one hand, the CISS effect underpins th…
Recent grants
NSF · $300k · 2011–2014
New Families of Molecules and Designed Interactions for Supramolecular Assembly
NSF · $490k · 2010–2013
High-Throughput Nanometer-Scale Chemical Patterning for Nanomanufacturing
NSF · $300k · 2016–2019
Frequent coauthors
- 215 shared
Oliver Reiser
University of Regensburg
- 215 shared
Eric F. Bell
University of Michigan–Ann Arbor
- 215 shared
Dagobert D. Runes
- 215 shared
Niels Bohr
- 215 shared
R. W. Gerard
Laboratoire des Sciences du Numérique de Nantes
- 215 shared
W Crozier
- 215 shared
C Ducasse
University of California, Berkeley
- 214 shared
Henry Margenau
Education
- 1986
Ph.D., Chemistry
UC Berkeley College of Chemistry
- 1980
S.M., Chemistry
Massachusetts Institute of Technology
- 1980
S.B., Chemistry
Massachusetts Institute of Technology
Awards & honors
- National Science Foundation (NSF) Presidential Young Investi…
- B. F. Goodrich Collegiate Inventors Award (1994)
- Alfred P. Sloan Foundation Fellowship (1995-97)
- American Chemical Society (ACS) Nobel Laureate Signature Awa…
- John Simon Guggenheim Memorial Foundation Fellowship (1997)
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