About

Dr. Neda Dianati Maleki, MD, MS, is a Clinical Assistant Professor in Medicine at Stony Brook Internists - Cardiology, located in Commack, NY. She specializes in cardiology with a focus on nuclear cardiology and advanced echocardiography. Dr. Maleki completed her medical degree at Iran University of Medical Sciences and Health Services School of Medicine in 2009. She further specialized through fellowships at Stony Brook University Medical Center in Advanced and Interventional Echocardiography in 2020 and in Internal Medicine-Cardiology in 2019. Her residency was completed at Mount Sinai - St. Luke's Roosevelt in Internal Medicine in 2016. She holds board certifications in Adult Comprehensive Echocardiography from the National Board of Echocardiography, and in Cardiovascular Disease and Internal Medicine from the American Board of Internal Medicine, obtained in 2019 and 2016 respectively. Dr. Maleki's professional focus includes comprehensive echocardiography and nuclear cardiology, and she is actively involved in clinical practice at Stony Brook University Hospital and affiliated locations.

Research topics

• Medicine
• Internal medicine
• Cardiology
• Radiology
• Anatomy
• Intensive care medicine

Selected publications

• 26-CCC-21201-ACC RETROGRADE TRANSCATHETER CLOSURE OF A RARE AORTO-LEFT ATRIAL FISTULA AS A SEQUELA OF PREVIOUS ENDOCARDITIS

  Journal of the American College of Cardiology · 2026-03-27

  articleSenior author
  PublisherDOI

• Closure of symptomatic mitral paravalvular leak following recent transcatheter mitral valve-in-ring

  ˜The œJournal of invasive cardiology/˜The œjournal of invasive cardiology · 2026-04-15

  article

  An 86-year-old man who had undergone recent transcatheter mitral valve-in-ring at an outside hospital presented with multiple hospitalizations for symptomatic hemolytic anemia requiring blood transfusions. Transesophageal echocardiogram demonstrated mitral paravalvular leak originating laterally between the transcatheter valve and surgical ring.

  PublisherDOI

• 26-CCC-13960-ACC TAVR FOLLOWING VALVE-SPARING AORTIC ROOT REPLACEMENT - IMAGING AND PROCEDURAL CHALLENGES

  Journal of the American College of Cardiology · 2026-03-27

  article
  PublisherDOI

• Patients with patent foramen ovale or atrial septal defect have worse outcomes after pulmonary vein isolation

  European Heart Journal · 2025-11-01

  article

  Abstract Background Patients with patent foramen ovale (PFO) and atrial septal defect (ASD) are known to have increased rates of atrial fibrillation (AF) from chronic atrial stretch, dilation, and remodeling. Closure of these shunts is also associated with increased short-term risk of AF development through postulated mechanisms of local irritation, tissue stretch, and left atrial strain. In patients undergoing pulmonary vein isolation (PVI), the effect of a PFO or ASD on AF recurrence remains unknown. Purpose To determine the effect of PFO/ASD on AF recurrence in patients undergoing PVI. Methods This retrospective cohort study was performed with TriNetX, a global health research network with over 130 million patients enrolled via electronic health record data. We examined adults over age 18 undergoing PVI, using Current Procedural Terminology coding, from earliest available enrollment as remote as 20 years prior to November 2022. Patients were separated into cohorts with either a pre-existing PFO or ASD versus neither based on International Classification of Diseases codes. The cohorts were balanced via propensity-score matching (PSM) with the following covariates: age, gender, race, comorbidities (hypertension, ischemic heart disease/atherosclerosis, heart failure/cardiomyopathy, cerebrovascular disease, obstructive sleep apnea, diabetes mellitus, obesity, chronic kidney disease), left ventricular ejection fraction, body mass index, and cardiovascular medications. Outcomes included mortality, hospitalization, redo AF ablation, direct current cardioversion (DCCV), antiarrhythmic drug (AAD) use, and stroke for a two-year follow-up period from index procedure. Results We examined a total of 53 healthcare organizations and 81,442 patients without a PFO or ASD and 2,884 patients with one. After applying PSM, each cohort included 2,804 patients. The average age was 63.8 years, 35.3% of patients were female, and average LVEF was 52.9%. In patients undergoing PVI, those with a PFO or ASD had significantly increased hospitalizations (HR 1.14, 95% CI 1.04-1.25, p<0.01), DCCVs (HR 1.18, 95% CI 1.05-1.33, p<0.01), AAD use (HR 1.12, 95% CI 1.05-1.20, p<0.01), and strokes (HR 1.36, 95% CI 1.09-1.68, p<0.01). No significant associations in mortality or redo ablations were observed. Conclusion In patients with AF undergoing PVI, those with a pre-existing PFO or ASD had less freedom from AF, increased hospitalizations, and more strokes.

  PublisherDOI

• Point of Care Ultrasound (POCUS) in the Management of Heart Failure: A Narrative Review

  Journal of Personalized Medicine · 2024 · 14 citations

  • Medicine
  • Cardiology
  • Radiology

  Assessing for volume overload is a key component of both short and long-term management of heart failure patients. Physical examination findings are neither sensitive nor specific for detecting congestion, and subclinical congestion may not be evident at the time of examination. Point of care ultrasound (POCUS) is an efficient and non-invasive way to assess heart failure patients for volume overload. The aim of our narrative review is to summarize how each of the following ultrasound modalities can be used to assess for congestion in the heart failure population: 2D and Doppler echocardiography, lung ultrasound, inferior vena cava ultrasound, internal jugular vein ultrasound, and venous excess grading. While each of these modalities has their limitations, their use in the acute and outpatient space offers the potential to reduce heart failure readmissions and mortality.

  PublisherOA PDFDOI

• ASSOCIATION OF LEFT ATRIAL STRAIN WITH OUTCOMES IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY

  Journal of the American College of Cardiology · 2024-04-01

  articleOpen access
  PublisherDOI

• INTRADEVICE LEAK: A RARE BUT IMPORTANT COMPLICATION AFTER LEFT ATRIAL APPENDAGE OCCLUSION

  Journal of the American College of Cardiology · 2024-04-01

  article
  PublisherDOI

• “FROSTY FINGERS, FIERY CHEST PAIN”- VASOSPASTIC ANGINA IN A PATIENT WITH RAYNAUD'S SYNDROME

  Journal of the American College of Cardiology · 2024-04-01

  article
  PublisherDOI

• Abstract 17328: A Case of Reversible Severe Systolic Cardiomyopathy; Thinking Outside the Box

  Circulation · 2023

  Senior authorCorresponding
  • Medicine
  • Internal medicine
  • Cardiology

  Introduction: Non-ischemic systolic cardiomyopathy is associated with significant morbidity and mortality. Prompt evaluation and timely removal of the potential insult may lead to reverse remodeling and recovery of the left ventricular (LV) systolic function. Case: A 39-year-old female with BMI 40 presented with dyspnea and bilateral lower extremity edema. Vital signs significant for mild tachycardia and hypertension. ECG showed sinus tachycardia. Physical exam revealed bibasilar crackles and 3+ pitting edema of the lower extremities. Laboratory significant for NTpro BNP 563 pg/dL and TSH <0.005 IU/mL with a free T4 of 2.73 ng/dL. Chest x-ray showed pulmonary vascular congestion. Echocardiogram showed severely reduced LV systolic function with ejection fraction (EF) of 27%, global LV hypokinesis and diastolic LV diameter of 6.85 cm. No significant atrial or ventricular arrhythmias noted on Telemetry. A CT angiography of the coronary arteries showed no evidence of calcification or obstructive coronary disease. Additional labs revealed severely elevated TSH receptor antibody and thyroid stimulating immunoglobulin. Diffuse thyroid enlargement noted on ultrasound. Patient was diagnosed with Grave’s disease (GD) with Burch-Wartofsky score of 30 indicating an impending thyroid storm. She was treated with Metoprolol and Methimazole. She underwent intravenous diuresis and was started on guideline-directed medical therapy for systolic cardiomyopathy. In follow-up after 6 months, her TSH had normalized. On repeat imaging, her LVEF improved to > 50% with diastolic LV diameter of 5.6 cm. Discussion: This patient was diagnosed with non-ischemic dilated systolic cardiomyopathy due to severe hyperthyroidism from GD. Thyrotoxicosis-induced systolic cardiomyopathy occurs in about 1% of patients with GD and is associated with increased morbidity and mortality. Excess thyroid hormones in thyrotoxicosis can affect multiple regulatory and structural genes of cardiac myocytes resulting in abnormal intracellular calcium regulation and impaired LV systolic and diastolic function. Our experience is consistent with literature demonstrating the importance of timely diagnosis and treatment of this reversible cause of systolic cardiomyopathy.

  PublisherDOI

• CRT-600.34 Are There Gender Disparities in Presentation and Left Atrial Anatomy in Adults With Atrial Fibrillation Undergoing Watchman Left Atrial Appendage Occlusion?

  КАРДИОЛОГИЯ УЗБЕКИСТАНА · 2020

  • Medicine
  • Cardiology
  • Internal medicine
  PublisherDOI

Frequent coauthors

• Paul W. Armstrong

  Canadian VIGOUR Centre

  11 shared

• Arash Afshar

  10 shared

• Yinggan Zheng

  University of Alberta

  9 shared

• Cynthia M. Westerhout

  University of Alberta

  8 shared

• Puja B. Parikh

  5 shared

• Yuling Fu

  State Key Laboratory of Respiratory Disease

  4 shared

• Ahmed Awad

  4 shared

• Pushpa Jagasia

  Canadian VIGOUR Centre

  4 shared