
Michael Rubinstein
· Adjunct ProfessorUniversity of North Carolina at Chapel Hill · Physiology and Pharmacology
Active 1962–2025
Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.
Research topics
- Organic chemistry
- Nanotechnology
- Computer Science
- Data Mining
- Materials science
- Chemistry
- Anesthesia
- Biology
- Ecology
- Physiology
Selected publications
DreamBooth: Fine Tuning Text-to-Image Diffusion Models for Subject-Driven Generation
2023-06-01 · 1940 citations
articleLarge text-to-image models achieved a remarkable leap in the evolution of AI, enabling high-quality and diverse synthesis of images from a given text prompt. However, these models lack the ability to mimic the appearance of subjects in a given reference set and synthesize novel renditions of them in different contexts. In this work, we present a new approach for “personalization” of text-to-image diffusion models. Given as input just a few images of a subject, we fine-tune a pretrained text-to-i…
Physiology and pathophysiology of human airway mucus
Physiological Reviews · 2022 · 318 citations
secretory rates to maintain mucus hydration in health. In disease, mucus becomes hyperconcentrated (dehydrated). Multiple mechanisms derange the ion transport pathways that normally hydrate mucus in muco-obstructive lung diseases, e.g., cystic fibrosis (CF), chronic obstructive pulmonary disease (COPD), non-CF bronchiectasis (NCFB), and primary ciliary dyskinesia (PCD). A key step in muco-obstructive disease pathogenesis is the osmotic compression of the mucus layer onto the airway surface with…
Molecular Characterization of Polymer Networks
Chemical Reviews · 2021 · 314 citations
Senior authorCorrespondingPolymer networks are complex systems consisting of molecular components. Whereas the properties of the individual components are typically well understood by most chemists, translating that chemical insight into polymer networks themselves is limited by the statistical and poorly defined nature of network structures. As a result, it is challenging, if not currently impossible, to extrapolate from the molecular behavior of components to the full range of performance and properties of the entire p…
arXiv (Cornell University) · 2023-11-02 · 4 citations
preprintOpen accessWe propose a new approach for generative modeling based on training a neural network to be idempotent. An idempotent operator is one that can be applied sequentially without changing the result beyond the initial application, namely $f(f(z))=f(z)$. The proposed model $f$ is trained to map a source distribution (e.g, Gaussian noise) to a target distribution (e.g. realistic images) using the following objectives: (1) Instances from the target distribution should map to themselves, namely $f(x)=x$.…
Unbounded: A Generative Infinite Game of Character Life Simulation
arXiv (Cornell University) · 2024-10-24 · 2 citations
preprintOpen accessWe introduce the concept of a generative infinite game, a video game that transcends the traditional boundaries of finite, hard-coded systems by using generative models. Inspired by James P. Carse's distinction between finite and infinite games, we leverage recent advances in generative AI to create Unbounded: a game of character life simulation that is fully encapsulated in generative models. Specifically, Unbounded draws inspiration from sandbox life simulations and allows you to interact with…
Recent grants
Molecular Model of Airway Surface Layer
NSF · $390k · 2006–2009
Topological Interactions in Polymer Gels
NSF · $290k · 2009–2013
Core D: Pharmacokinetics/Pharmacodynamics Core
NIH · $5.1M · 2017–2017
Frequent coauthors
- 186 shared
Dimitris Vlassopoulos
FORTH Institute of Electronic Structure and Laser
- 172 shared
Taihyun Chang
Pohang University of Science and Technology
- 163 shared
Pierre J. Lutz
Focus (Germany)
- 100 shared
Daniele Parisi
University of Groningen
- 91 shared
Salvatore Costanzo
FORTH Institute of Electronic Structure and Laser
- 86 shared
Wim Pyckhout‐Hintzen
Forschungszentrum Jülich
- 86 shared
Dieter Richter
Forschungszentrum Jülich
- 86 shared
Junyoung Ahn
Pohang University of Science and Technology
Education
- 1983
Ph.D in Physics
Harvard University
- 1980
MA
Harvard University
- 1979
BS in Physics
California Institute of Technology
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