Matthias Benz
· Associate ProfessorUniversity of California, Los Angeles · Nuclear Medicine & Theranostics
Active 1994–2026
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About
Matthias Benz is an Associate Professor in the Department of Pharmacology at the University of California, Los Angeles. His diagnostic clinical and research activities are centered on the use of advanced imaging modalities such as positron emission tomography (PET) and diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging (MRI) for the non-invasive diagnosis, staging, treatment response assessment, and follow-up of patients with cancer. He holds an M.D. degree and has a background that includes positions at the University Hospital Basel in Switzerland, where he served as an Assistant Professor of Radiology and Nuclear Medicine, as well as a resident in Nuclear Medicine and Radiology. Benz has also been a research fellow at UCLA's Ahmanson Translational Imaging Division and Nuclear Medicine. His academic career includes appointments as an Assistant Professor in the Departments of Radiological Sciences and Molecular and Medical Pharmacology at UCLA. His work integrates clinical imaging techniques with research to improve cancer diagnosis and management.
Research topics
- Medicine
- Internal medicine
- Nuclear medicine
- Oncology
- Radiology
- Biology
- Pathology
Selected publications
Journal of Nuclear Medicine · 2022 · 134 citations
Lu-PSMA in men with mCRPC. PSA + RECIP may be used as a novel composite endpoint in mCRPC clinical trial design.
Radiology · 2023-07-01 · 99 citations
articleOpen accessBackground Response Evaluation Criteria in Prostate-specific Membrane Antigen (PSMA) PET/CT (RECIP 1.0) initially integrated software-based quantitative assessment of PSMA-positive total tumor volume (TTV). Clinical implementation of such software is not expected soon, limiting the use of RECIP in practice. Purpose To assess the agreement of RECIP determined using tumor segmentation software (quantitative RECIP) with RECIP determined by qualitative reads by nuclear medicine physicians (visual RE…
European Journal of Nuclear Medicine and Molecular Imaging · 2022 · 99 citations
Senior authorCorrespondingJAMA Network Open · 2025-01-03 · 54 citations
articleOpen accessImportance: The phase 3 randomized EMBARK trial evaluated enzalutamide with or without leuprolide in high-risk nonmetastatic hormone-sensitive prostate cancer. Eligibility relied on conventional imaging, which underdetects metastatic disease compared with prostate-specific membrane antigen-positron emission tomography (PSMA-PET). Objective: To describe the staging information obtained by PSMA-PET/computed tomography (PSMA-PET/CT) in a patient cohort eligible for the EMBARK trial. Design, Setting…
Fibroblast Activation Protein Expression in Sarcomas
Sarcoma · 2023-06-09 · 38 citations
articleOpen accessObjectives. Fibroblast activation protein alpha (FAP) is highly expressed by cancer-associated fibroblasts in multiple epithelial cancers. The aim of this study was to characterize FAP expression in sarcomas to explore its potential utility as a diagnostic and therapeutic target and prognostic biomarker in sarcomas. Methods. Available tissue samples from patients with bone or soft tissue tumors were identified at the University of California, Los Angeles. FAP expression was evaluated via immunoh…
Frequent coauthors
- 81 shared
William D. Tap
- 80 shared
Fritz C. Eilber
University of California, Los Angeles
- 69 shared
Daniel Braas
- 69 shared
Ethan Ahler
- 69 shared
Kathleen B. Smith
- 69 shared
Brenna Tam
- 69 shared
Mirielle Riedinger
- 67 shared
David A. Nathanson
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