
Lorenz Biegler
· Covestro University Professor, Director, Center for Advanced Process Decision-makingCarnegie Mellon University · Chemical Engineering
Active 1965–2026
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About
Professor Lorenz T. Biegler is the Covestro University Professor of Chemical Engineering at Carnegie Mellon University. His research focuses on the development and application of optimization and numerical methods for process design, analysis, operations, and control in chemical engineering. His work includes advanced algorithms for flowsheet simulation, optimization, and sensitivity analysis, with an emphasis on numerical methods for challenging process applications. He has developed interior point and active set algorithms for nonlinear programming and nonlinear complementarity problems, as well as efficient decomposition strategies that serve as core solvers in process design, control, and operations. Professor Biegler's research prioritizes efficient methods for large-scale optimization problems arising in chemical engineering and energy systems. He also works on large-scale nonlinear programming methods for systems of differential and algebraic equations (DAEs), addressing stability, accuracy, optimal control problems, and large-scale nonlinear programming formulations applicable to batch processes, fuel cells, dynamic separations, biological fermentations, and polymerization reactors. Additionally, his research includes real-time algorithms for nonlinear estimation, control, and optimization, applying maximum likelihood and optimization concepts for parameter estimation, data reconciliation, and gross error detection in steady and dynamic problems. These methods are…
Research topics
- Computer Science
- Engineering
- Mathematical optimization
- Mathematics
- Distributed computing
- Software engineering
- Operating system
- Physics
- Systems engineering
- Mathematical analysis
Selected publications
Journal of Advanced Manufacturing and Processing · 2021 · 109 citations
Abstract Energy systems and manufacturing processes of the 21st century are becoming increasingly dynamic and interconnected, which require new capabilities to effectively model and optimize their design and operations. Such next generation computational tools must leverage state‐of‐the‐art techniques in optimization and be able to rapidly incorporate new advances. To address these requirements, we have developed the Institute for the Design of Advanced Energy Systems (IDAES) Integrated Platform…
AIChE Journal · 2020 · 30 citations
Senior authorCorrespondingAbstract We propose a new strategy to synthesize heat exchanger networks with detailed designs of individual heat exchangers. The proposed strategy uses a multistep approach by first obtaining a heat exchanger network topology through solving a modified version of the mixed integer nonlinear programming (MINLP) stage‐wise superstructure of Yee and Grossmann, which includes a smoothed LMTD approximation and pressure drops. In a second nonlinear programming (NLP) suboptimization step, we allow for…
Dynamic optimization with complementarity constraints: Smoothing for direct shooting
Computers & Chemical Engineering · 2020 · 22 citations
Computers & Chemical Engineering · 2025-08-28 · 3 citations
articleOpen accessIn this study, we develop and implement a reactive transport model in COMSOL Multiphysics® to address the challenges of direct air carbon capture. The model is validated against experimental data and used to simulate the cyclic steady state of the adsorption-desorption process. The optimization of this model is achieved through advanced trust-region methods integrated with Gaussian Processes. Key decision variables, including adsorption and desorption times, desorption temperature and pressure,…
Surrogate model optimization: a comparison case study with pooling problems of CO2 point sources
Computers & Chemical Engineering · 2025-05-18 · 2 citations
articleOpen accessSenior authorIn this work, we present a benchmark study to leverage the implementation of surrogate models (SMs) within mathematical optimization problems for the integration of carbon capture technologies within an industrial complex, focusing on the pooling of CO₂ streams to enhance efficiency and reduce capture costs. The SMs are built using data from rigorous process simulations in Aspen Plus, with each data point generated by solving equation-oriented optimization problems. We evaluate five different SM…
Recent grants
Algorithmic Advances for Large-Scale Dynamic Process Optimization
NSF · $304k · 2003–2007
Collaborative Proposal: Large-Scale Optimization Strategies for Design under Uncertainty
NSF · $251k · 2005–2009
GOALI: Fast Nonlinear Model Predictive Control for Dynamic Real-time Optimization
NSF · $332k · 2012–2016
Frequent coauthors
- 66 shared
Stephen E. Zitney
National Energy Technology Laboratory
- 44 shared
Zhijiang Shao
Zhejiang University
- 42 shared
Sachin C. Patwardhan
- 40 shared
Yidong Lang
Carnegie Mellon University
- 36 shared
Myung S. Jhon
Carnegie Mellon University
- 33 shared
Anshul Agarwal
- 32 shared
Rui Huang
- 31 shared
Carl D. Laird
Labs
Develops and applies optimization and numerical methods for process design, analysis, operations, and control.
Education
- 1981
Ph.D., Chemical Engineering
University of Wisconsin, Madison
- 1979
M.S., Chemical Engineering
University of Wisconsin, Madison
- 1977
B.S., Chemical Engineering
Illinois Institute of Technology
Awards & honors
- Sargent Medal (2022) by IChemE
- Control Magazine’s Hall of Fame (2022)
- Long-Term Achievements Award in Computer-Aided Process Engin…
- Honorary doctorate in engineering sciences from the Technica…
- Fellow of AIChE
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