Lawrence Price

About

Lawrence H. Price is a Professor of Psychiatry and Human Behavior at Brown University. He received his B.S. with highest honors in psychology and high distinction from the University of Michigan in 1974, followed by an M.D. in 1978. After completing an internship in internal medicine at Norwalk Hospital, he completed a residency and fellowship in psychiatry at Yale University. From 1982 to 1996, he was on the faculty at Yale University’s Department of Psychiatry, serving as Associate Professor and Director of the Clinical Neuroscience Research Unit at the Connecticut Mental Health Center. Since 1996, he has been a faculty member at Brown University. He has held leadership roles at Butler Hospital, including Clinical Director, Director of Research, Chair of the Institutional Review Board, and Chief Medical Officer. Currently, he is President of Butler Hospital and Executive Chief of the Brain and Behavioral Health Service Line of Care New England. Dr. Price has been recognized by the Institute for Scientific Information as one of the top ten authors of high-impact papers in psychiatry from 1990 to 1999. His research focuses on neurobiological mechanisms underlying psychiatric disorders, with particular attention to the effects of early adversity, treatment mechanisms, and neurobiological markers such as telomere length and mitochondrial DNA copy number. In addition to his research, he has received numerous awards for teaching and clinical work, and he serves as editor for the…

Research topics

• Psychology
• Medicine
• Internal medicine
• Genetics
• Biology
• Psychiatry

Selected publications

• Molecular markers of neuroendocrine function and mitochondrial biogenesis associated with early life stress

  Psychoneuroendocrinology · 2020 · 34 citations

  DOI

• Modeling the antidepressant treatment response to transcranial magnetic stimulation using an exponential decay function

  Scientific Reports · 2023-05-02 · 13 citations

  articleOpen access

  Recovery from depression often demonstrates a nonlinear pattern of treatment response, where the largest reduction in symptoms is observed early followed by smaller improvements. This study investigated whether this exponential pattern could model the antidepressant response to repetitive transcranial magnetic stimulation (TMS). Symptom ratings from 97 patients treated with TMS for depression were collected at baseline and after every five sessions. A nonlinear mixed-effects model was constructe…

  PublisherOA PDFDOI

• Randomized Controlled Trial of Aerobic Exercise for Smoking Cessation Among Individuals With Elevated Depressive Symptoms

  Nicotine & Tobacco Research · 2023-10-11 · 4 citations

  articleOpen access

  INTRODUCTION: Adults with depression have higher rates of cigarette smoking and are more likely to relapse than those without depression. Pharmacological, psychological, and combined interventions have largely yielded small improvements in smoking outcomes for adults with depression. Aerobic exercise (AE) may facilitate smoking cessation in this subpopulation. METHODS: This study was a 12-week two-arm randomized controlled trial that evaluated the effect of a moderate-intensity AE program compar…

  PublisherOA PDFDOI

• Circulating Cell-Free Mitochondrial DNA and Depressive Symptoms Among Low-Active Adults Who Smoke

  Psychosomatic Medicine · 2023-09-28 · 2 citations

  articleOpen access

  OBJECTIVES: Mitochondrial dysfunction is implicated in the pathophysiology of psychiatric disorders. Levels of circulating cell-free mitochondrial DNA (cf-mtDNA) are observed to be altered in depression. However, the few studies that have measured cf-mtDNA in depression have reported conflicting findings. This study examined cf-mtDNA and depressive symptoms in low-active adults who smoke. METHODS: Participants were adults 18 to 65 years old ( N = 109; 76% female) with low baseline physical activ…

  PublisherOA PDFDOI

• Suicidality and psychotropic drugs: Another perspective

  The Brown University Psychopharmacology Update · 2025-08-04 · 1 citations

  article1st authorCorresponding
  PublisherDOI

Recent grants

• NIH Grant K08MH000579

  NIH · $193k · 1990

• NIH Grant R01DA009330

  NIH · $714k · 2000

• NIH Grant R01AT001742

  NIH · $1.0M · 2010

Frequent coauthors

• Seiya Miyamoto

  5101 shared

• MacDonald J. Christie

  University of Sydney

  4627 shared

• Kim Wolff

  King's College London

  4464 shared

• Martine Cador

  Institut de Neurosciences Cognitives et Intégratives d’Aquitaine

  3235 shared

• Malcolm Lader

  3048 shared

• Robert L. Balster

  3010 shared

• Kim Fromme

  The University of Texas at Austin

  2995 shared

• Amee B. Patel

  Syneos Health (United States)

  2994 shared

Education

• B.S., Psychology

  University of Michigan

  1974

• M.D.

  University of Michigan

  1978

Awards & honors

• Top ten authors of high-impact papers in psychiatry by Insti…

Similar researchers at Brown University

• Karen Furieh-148
• Rena Wingh-146
• Richard Jonesh-126