Kristina Anderson

About

Kristina (Tina) Anderson is an HR and organizational development leader with expertise in data-based approaches to diagnosing and solving organizational challenges. She specializes in employee communications, change management, talent management, leadership development, and HR program design across the employee life cycle. Her work spans several industries, including aviation, architecture, consumer packaged goods, financial services, government, healthcare, manufacturing, marketing and brand management, non-profit, pharmaceutical, publishing, retail, and technology. Tina holds a Master’s degree in Industrial-Organizational Psychology from NYU, a certificate in Organization & Leadership Development from NYU, a Master’s degree in English & American Literature from the University of Wisconsin-Madison, and a Bachelor’s degree in English Literature from Brown University.

Research topics

• Medicine
• Internal medicine
• Chemistry
• Endocrinology
• Biology

Selected publications

• Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria

  New England Journal of Medicine · 2020-06-10 · 591 citations

  articleOpen access

  BACKGROUND: Up-regulation of hepatic delta-aminolevulinic acid synthase 1 (ALAS1), with resultant accumulation of delta-aminolevulinic acid (ALA) and porphobilinogen, is central to the pathogenesis of acute attacks and chronic symptoms in acute hepatic porphyria. Givosiran, an RNA interference therapy, inhibits ALAS1 expression. METHODS: In this double-blind, placebo-controlled, phase 3 trial, we randomly assigned symptomatic patients with acute hepatic porphyria to receive either subcutaneous g…

  PublisherOA PDFDOI

• Hepatocellular Carcinoma in Acute Hepatic Porphyrias: Results from the Longitudinal Study of the U.S. Porphyrias Consortium

  Hepatology · 2020-07-18 · 49 citations

  article

  BACKGROUND AND AIMS: The risk for hepatocellular carcinoma (HCC) is increased in acute hepatic porphyrias (AHP). The aim of this study was to explore the clinicopathologic characteristics, outcomes, and frequency of HCC in patients with AHP in the United States. APPROACH AND RESULTS: This cross-sectional analysis evaluated patients with HCC in a multicenter, longitudinal study of AHP. Among 327 patients with AHP, 5 (1.5%) were diagnosed with HCC. Of the 5 HCC cases, 4 had acute intermittent porp…

  PublisherDOI

• Biochemical Diagnosis of Acute Hepatic Porphyria: Updated Expert Recommendations for Primary Care Physicians

  The American Journal of the Medical Sciences · 2021-04-16 · 47 citations

  reviewOpen access1st authorCorresponding

  Acute hepatic porphyria (AHP) is a group of rare, metabolic diseases where patients can experience acute neurovisceral attacks, chronic symptoms, and long-term complications. Diagnostic biochemical testing is widely available and effective, but a substantial time from symptom onset to diagnosis often delays treatment and increases morbidity. A panel of laboratory scientists and clinical AHP specialists collaborated to produce recommendations on how to enhance biochemical diagnosis of AHP in the…

  PublisherOA PDFDOI

• Mo1655: A PROSPECTIVE, BLINDED STUDY OF SYMPTOM PREVALENCE AND SPECIFICTY OF PORPHYRIN PRECURSORS IN CARRIERS OF ACUTE HEPATIC PORPHYRIA

  Gastroenterology · 2025-05-01

  article
  PublisherDOI

Recent grants

• Phase 2 Study of Hemin for Treatment and Prevention of Porphyria Attacks

  NIH · $1.3M · 2013–2021

• NIH Grant M01RR000073

  NIH · $12.9M · 2010

• NIH Grant R21DK073093

  NIH · $444k · 2010

Frequent coauthors

• Attallah Kappas

  Rockefeller University

  181 shared

• Allan H. Conney

  Rutgers, The State University of New Jersey

  172 shared

• Eugene J. Pantuck

  Columbia University

  168 shared

• Carol B. Pantuck

  Columbia University

  152 shared

• Robert J. Desnick

  Icahn School of Medicine at Mount Sinai

  132 shared

• Herbert L. Bonkovsky

  Atrium Health Wake Forest Baptist

  128 shared

• Joseph R. Bloomer

  University of Alabama at Birmingham

  97 shared

• Claus A. Pierach

  University of Minnesota Medical Center

  82 shared