Karla Zadnik

About

Karla Zadnik is Dean of the College of Optometry and Glenn A. Fry Professor of Optometry and Physiological Optics at The Ohio State University. She is an esteemed patient-oriented researcher in the field of optometry and vision science. Dean Zadnik served as the study chairman for the National Eye Institute-funded Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study for 20 years and chaired the first-ever National Eye Institute-funded multicenter study based in optometry, the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study. She has held leadership roles as a past president of the American Academy of Optometry, the Association of Schools and Colleges of Optometry, and the National Board of Examiners in Optometry. Additionally, she served a four-year term on the National Advisory Eye Council for the National Eye Institute/National Institutes of Health. In recognition of her contributions, she received the Academy's Prentice Award in 2020.

Research topics

• Medicine
• Ophthalmology
• Optometry
• Political Science
• Internal medicine
• Anesthesia
• Gerontology
• Physics
• Optics
• Physical therapy

Selected publications

• Prediction of Juvenile-Onset Myopia

  JAMA Ophthalmology · 2015-04-02 · 366 citations

  articleOpen access1st authorCorresponding

  IMPORTANCE: Myopia (nearsightedness) has its onset in childhood and affects about one-third of adults in the United States. Along with its high prevalence, myopia is expensive to correct and is associated with ocular diseases that include glaucoma and retinal detachment. OBJECTIVE: To determine the best set of predictors for myopia onset in school-aged children. DESIGN, SETTING, AND PARTICIPANTS: The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study was an ob…

  PublisherOA PDFDOI

• Myopia Progression as a Function of Sex, Age, and Ethnicity

  Investigative Ophthalmology & Visual Science · 2021 · 135 citations

  Senior authorCorresponding

  Purpose: To model juvenile-onset myopia progression as a function of race/ethnicity, age, sex, parental history of myopia, and time spent reading or in outdoor/sports activity. Methods: Subjects were 594 children in the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study with at least three study visits: one visit with a spherical equivalent (SPHEQ) less myopic/more hyperopic than -0.75 diopter (D), the first visit with a SPHEQ of -0.75 D or more myopia (onset…

  PublisherDOI

• Reducing the Global Burden of Myopia by Delaying the Onset of Myopia and Reducing Myopic Progression in Children

  Ophthalmology · 2020 · 117 citations

  Senior authorCorresponding
  PublisherDOI

• Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years

  JAMA Ophthalmology · 2023 · 116 citations

  1st authorCorresponding

  Importance: The global prevalence of myopia is predicted to approach 50% by 2050, increasing the risk of visual impairment later in life. No pharmacologic therapy is approved for treating childhood myopia progression. Objective: To assess the safety and efficacy of NVK002 (Vyluma), a novel, preservative-free, 0.01% and 0.02% low-dose atropine formulation for treating myopia progression. Design, Setting, and Participants: This was a double-masked, placebo-controlled, parallel-group, randomized ph…

  PublisherOA PDFDOI

• The Effect of Age, Accommodation, and Refractive Error on the Adult Human Eye

  Optometry and Vision Science · 2015-12-23 · 78 citations

  articleOpen accessSenior authorCorresponding

  PURPOSE: To quantify changes in ocular dimensions associated with age, refractive error, and accommodative response, in vivo, in 30- to 50-year-old human subjects. METHODS: The right eyes of 91 adults were examined using ultrasonography, phakometry, keratometry, pachymetry, interferometry, anterior segment optical coherence tomography, and high-resolution magnetic resonance imaging. Accommodation was measured subjectively with a push-up test and objectively using open-field autorefraction. Regre…

  PublisherOA PDFDOI

Recent grants

• NIH Grant R21EY012273

  NIH · $526k · 2004

• NIH Grant U10EY008893

  NIH · $25.1M · 2013

• NIH Grant R24EY014792

  NIH · $1.0M · 2010

Frequent coauthors

• Donald O. Mutti

  264 shared

• G. Lynn Mitchell

  SUNY College of Optometry

  136 shared

• Joseph T. Barr

  The Ohio State University

  132 shared

• Timothy B. Edrington

  Marshall B. Ketchum University

  120 shared

• Mae O. Gordon

  88 shared

• Loraine T. Sinnott

  SUNY College of Optometry

  80 shared

• Mark A. Bullimore

  University of Houston

  68 shared

• Lisa Jones

  67 shared

Labs

• Karla Zadnik LabPI

Education

• Ph.D., Vision Science

  The Ohio State University

  2005

• M.S., Vision Science

  The Ohio State University

  2001

• B.S., Optometry

  The Ohio State University

  1998

Awards & honors

• Prentice Award (2020)

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• Jeffrey Wallineh-46