Karen I. Goldberg

About

Karen I. Goldberg is the Vagelos Professor of Energy Research at the University of Pennsylvania. Her professional focus areas include Energy Research, Inorganic Chemistry, and Materials Chemistry. She is based in Room 618 of the VLEST Building and can be contacted via kig@sas.upenn.edu or by phone at 215-573-6756. The information provided highlights her role and research interests within the Department of Chemistry at the University of Pennsylvania but does not include further details about her background or specific contributions.

Research topics

• Chemistry
• Organic chemistry
• Photochemistry
• Physical chemistry
• Inorganic chemistry
• Stereochemistry
• Medicinal chemistry
• Combinatorial chemistry

Selected publications

• A Metal-Free, Photocatalytic Method for Aerobic Alkane Iodination

  Journal of the American Chemical Society · 2021 · 27 citations

  Senior authorCorresponding

  CN is turnover-limiting.

  DOI

• Metal/Ligand Proton Tautomerism Facilitates Dinuclear H₂Reductive Elimination

  Journal of the American Chemical Society · 2020 · 27 citations

  Senior authorCorresponding

  . The tautomerization between the metal-hydride and the ligand protonated species provides a low energy pathway for ligand dissociation, opening the needed coordination site. The ability to control the interconversion between a metal-hydride and a ligand-protonated congener using an exogeneous ligand introduces a new strategy for catalyst design with proton responsive ligands.

  DOI

• (Hexamethylbenzene)Ru catalysts for the Aldehyde-Water Shift reaction

  Green Chemistry · 2021 · 19 citations

  Senior authorCorresponding

  The Aldehyde-Water Shift (AWS) reaction uses H₂O as a benign oxidant to convert aldehydes to carboxylic acids, producing H₂, a valuable reagent and fuel, as its sole byproduct.

  DOI

• Comparing Square-Planar Rh^I and Ir^I: Metal–Ligand Proton Tautomerism, Fluxionality, and Reactivity

  Organometallics · 2022-09-30 · 14 citations

  articleSenior authorCorresponding

  A series of low-valent square-planar Rh complexes [LHRh][X] (X = PF6, Br, Cl, I) bearing two protic imidazolyl phosphines (one κ2) and a CO ligand were synthesized and fully characterized. A comparison of the CO stretching frequencies with those of the previously reported [LHIr][X] complexes indicates a much lower electron density at the Rh centers. This lower electron density at Rh results in a lower propensity to undergo ligand to metal proton transfer, and in contrast to observations with Ir,…

  PublisherDOI

• Insertion of Molecular Oxygen into a Gold(III)–Hydride Bond

  Journal of the American Chemical Society · 2024-01-30 · 13 citations

  articleSenior authorCorresponding

  The use of molecular oxygen as an oxidant in chemical synthesis has significant environmental and economic benefits, and it is widely used as such in large-scale industrial processes. However, its adoption in highly selective homogeneous catalytic transformations, particularly to produce oxygenated organics, has been hindered by our limited understanding of the mechanisms by which O2 reacts with transition metals. Of particular relevance are the mechanisms of the reactions of oxygen with late tr…

  PublisherDOI

Recent grants

• Novel Platinum and Palladium Reactions Relevant to Hydrocarbon Functionalization

  NSF · $485k · 2010–2014

• Center for the Activation and Transformation of Strong Bonds (CATSB)

  NSF · $1.5M · 2004–2007

• Organometallic Reactions Relevant to the Functionalization of Alkanes

  NSF · $675k · 2002–2007

Frequent coauthors

• Werner Kaminsky

  University of Washington

  160 shared

• D. Michael Heinekey

  University of Washington

  98 shared

• Richard A. Kemp

  Iowa State University

  91 shared

• D.X. West

  70 shared

• Michael R. Gau

  40 shared

• Kyle A. Grice

  Belden (United States)

  36 shared

• D.R. Kelman

  33 shared

• K.A. Claborn

  30 shared

Awards & honors

• Raymon E. and Rosellen M. Lawton Distinguished Scholar in Ch…
• Nicole A. Boand Endowed Professor of Chemistry (2010)
• Director of the Center for Enabling New Technologies through…
• Inaugural Director of the Vagelos Institute of Energy Scienc…

Similar researchers at University of Pennsylvania

• Thomas Malloukh-143
• Tianquan “Tim” Lianh-91
• Joseph S. Franciscoh-68