Kairos Shen

About

Kairos Shen is the Associate Professor of the Practice at MIT’s Center for Real Estate (CRE), where he teaches the Real Estate Development Studio. Between 2020 and 2024, he served as the Executive Director, overseeing the Master of Science in Real Estate Development degree program as well as the CRE’s industry relations and partnerships. He advocates for the CRE’s interdisciplinary curriculum of “City Making,” which draws on knowledge, research, and practice across design, city planning, public policy, finance, and real estate. The curriculum aims to prepare students to address complex urban challenges such as social equity, housing affordability, climate resiliency, and infrastructure rebuilding. Prior to his academic role at MIT, Mr. Shen was the Director of Planning at the Boston Redevelopment Authority, Boston’s Economic Development and Planning Agency, and served as Boston’s Chief City Planner for thirteen years. In this capacity, he worked closely with the Mayor of Boston to develop and implement city planning and economic development policies, contributing to major initiatives including the development guidelines for the Rose Kennedy Greenway, the South Boston Waterfront Innovation District, the refurbishment of Fenway Park, and the revitalization of Nubian Square. He is a graduate of Swarthmore College and holds a Master of Architecture from MIT.

Research topics

• Biology
• Virology
• Computer Science
• Cell biology
• Medicine
• Genetics
• Internal medicine
• Biochemistry
• Computational biology

Selected publications

• Structures and Functions of the Human GATOR1 Complex

  Sub-cellular biochemistry/Subcellular biochemistry · 2024-01-01 · 2 citations

  reviewOpen accessSenior author
  PublisherOA PDFDOI

• Supplementary Table 2 from A Diverse Array of Cancer-Associated <i>MTOR</i> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity

  2023-04-03

  supplementary-materialsOpen access

  <p>XLSX file 31K, All MTOR mutations from a literature search and the cBIO, COSMIC, and ICGC databases are listed</p>

  PublisherDOI

• Supplementary Figure 3 from A Diverse Array of Cancer-Associated <i>MTOR</i> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity

  2023-04-03

  preprintOpen access

  <p>PDF file 94K,Non-recurrent MTOR mutations confer different degrees of mTORC1 activation</p>

  PublisherOA PDFDOI

• Supplementary Figure and Table Legends from A Diverse Array of Cancer-Associated <i>MTOR</i> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity

  2023-04-03

  preprintOpen access

  <p>PDF file 82K, Supplementary Figure and Table Legends</p>

  PublisherOA PDFDOI

• Supplementary Table 4 from A Diverse Array of Cancer-Associated <i>MTOR</i> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity

  2023-04-03

  supplementary-materialsOpen access

  <p>XLSX file 12K, All activating MTOR mutations from this study are listed</p>

  PublisherDOI

Recent grants

• A Molecular Study of Rag GTPase-Dependent Amino Acid Sensing

  NIH · $204k · 2020–2022

• Spatial and temporal regulation of nutrient sensing

  NIH · $1.8M · 2022–2027

Frequent coauthors

• David M. Sabatini

  Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

  318 shared

• Lynne Chantranupong

  Howard Hughes Medical Institute

  94 shared

• Pascal Houillier

  Université Paris Cité

  92 shared

• Rachel L. Wolfson

  Harvard University

  63 shared

• Gregory A. Wyant

  Harvard University

  60 shared

• Andrew H. Beck

  AstraZeneca (United Kingdom)

  57 shared

• Sumi Sinha

  57 shared

• Valentina Nardi

  57 shared

Education

• PhD, Chemistry and Chemical Engineering

  California Institute of Technology

  2013

• BS, School of Chemistry and Materials Science

  University of Science and Technology of China

  2007

Similar researchers at Massachusetts Institute of Technology

• Siqi Zhengh-48
• William C. Wheatonh-42
• Albert Saizh-27