Jorge Galán, PhD, DVM
· Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell BiologyYale University · Cell Biology
About
Our laboratory studies the molecular mechanisms of pathogenesis of Salmonella spp. and Campylobacter spp. Together, these bacterial pathogens are responsible for the majority of food-borne illnesses in the world. Although most often these bacteria cause self-limiting gastroenteritis, they can also cause life-threatening disease such as typhoid fever. To study these bacterial pathogens, we take a multidisciplinary approach that includes bacterial genetics, animal models, cell biology, immunology, and structural biology approaches. We aim to define the functional and, when possible, the atomic interface between these pathogens and their hosts, and in the process, to provide the bases for the development of novel prevention and therapeutic strategies to combat infectious diseases that are a global public health concern.
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