About

John Marshall is the Leonard and Helen R. Stulman Professor of History at Johns Hopkins University and serves as the Director of the interdisciplinary program in Political and Moral Thought. His research interests include Early Modern British and British Imperial History, Early Modern European Cultural and Intellectual History, and the History of Political Thought. Marshall holds a Bachelor’s and Master’s degree from Cambridge University, UK, where he also served as a Junior Research Fellow, a By-Fellow, and an Overseas Fellow. He earned a Master’s degree and PhD from Johns Hopkins University and is a Fellow of the Royal Historical Society. He has authored two books, co-edited a third, and is working on several more. His notable works include 'John Locke: Religion, Resistance, and Responsibility' and 'John Locke, Toleration and Early Enlightenment Culture,' both published by Cambridge University Press. His scholarship has been highly praised for its depth, scope, and contribution to understanding Locke’s moral, religious, and political thought, as well as the history of religious toleration and social, political, and philosophical ideas in early modern Europe. Marshall researches and presents on topics such as the political, religious, social, cultural, economic, gender, and intellectual history of London from 1640 to 1700, Islam and Toleration, and the thought of George Keith in international contexts. He works with graduate students on a wide range of topics within early modern British and British imperial history, European cultural and intellectual history, and the history of political thought. His teaching at Johns Hopkins includes courses on Early Modern Britain, the English Revolution, Popular Culture in Early Modern Europe, Renaissance to Enlightenment, and London’s history from 1580-1832.

Research topics

• Political Science
• Philosophy
• Environmental health
• Virology
• Medicine
• Psychoanalysis
• Law
• Epistemology
• Religious studies
• History
• Theology
• Mathematics
• Medical emergency
• Psychology
• Nursing

Selected publications

• How Social Media Creators Shape Mass Politics: A Field Experiment during the 2024 US Elections

  SSRN Electronic Journal · 2025-01-01

  preprintOpen access
  PublisherDOI

• Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis

  Intensive Care Medicine · 2024-10-21 · 8 citations

  reviewOpen access

  Medical progress is reflected in the advance from broad clinical syndromes to mechanistically coherent diagnoses. By this metric, research in sepsis is far behind other areas of medicine-the word itself conflates multiple different disease mechanisms, whilst excluding noninfectious syndromes (e.g., trauma, pancreatitis) with similar pathogenesis. New technologies, both for deep phenotyping and data analysis, offer the capability to define biological states with extreme depth. Progress is limited by a fundamental problem: observed groupings of patients lacking shared causal mechanisms are very poor predictors of response to treatment. Here, we discuss concrete steps to identify groups of patients reflecting archetypes of disease with shared underlying mechanisms of pathogenesis. Recent evidence demonstrates the role of causal inference from host genetics and randomised clinical trials to inform stratification analyses. Genetic studies can directly illuminate drug targets, but in addition they create a reservoir of statistical power that can be divided many times among potential patient subgroups to test for mechanistic coherence, accelerating discovery of modifiable mechanisms for testing in trials. Novel approaches, such as subgroup identification in-flight in clinical trials, will improve efficiency. Within the next decade, we expect ongoing large-scale collaborative projects to discover and test therapeutically relevant sepsis archetypes.

  PublisherDOI

• Climate Change Messages Can Promote Support for Climate Action Globally

  SSRN Electronic Journal · 2024-01-01 · 2 citations

  preprintOpen access
  PublisherDOI

• How Social Media Influencers Shape the Politics of Young Adults

  AEA Randomized Controlled Trials · 2024-07-09

  dataset1st authorCorresponding
  PublisherDOI

• Climate change messages can promote support for climate action globally

  Global Environmental Change · 2024-11-26 · 13 citations

  article
  PublisherDOI

• How Social Media Influencers Shape the Politics of Young Adults

  AEA Randomized Controlled Trials · 2024-07-09

  dataset1st authorCorresponding
  PublisherDOI

• How social media creators shape mass politics

  AEA Randomized Controlled Trials · 2024-07-09

  dataset1st authorCorresponding
  PublisherDOI

• How Social Media Influencers Shape the Politics of Young Adults

  AEA Randomized Controlled Trials · 2024-07-09

  dataset1st authorCorresponding
  PublisherDOI

• How Social Media Influencers Shape the Politics of Young Adults

  AEA Randomized Controlled Trials · 2024-07-09

  dataset1st authorCorresponding
  PublisherDOI

• Improved therapeutic efficacy in two mouse models of methylmalonic acidemia (MMA) using a second-generation mRNA therapy

  Molecular Genetics and Metabolism · 2024-08-05 · 15 citations

  article
  PublisherDOI

Frequent coauthors

• Barto Nascimento

  Universidade de São Paulo

  40 shared

• Julia M. Phillips

  Australian National University

  37 shared

• Andrew W. Kirkpatrick

  University of Calgary

  36 shared

• Chad G. Ball

  36 shared

• Homer Tien

  Health Sciences Centre

  36 shared

• Avery B. Nathens

  University of Toronto

  28 shared

• R. B. van Dover

  Cornell University

  28 shared

• Joao Rezende Neto

  St. Michael's Hospital

  28 shared

Awards & honors

• Fellow of the Royal Historical Society