John Carethers
· MD, MACP, FAACRUniversity of California, San Diego · Gastroenterology
Active 1987–2026
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About
John M. Carethers is the Vice Chancellor for Health Sciences at the University of California San Diego, where he also holds the titles of Distinguished Professor of Medicine and Adjunct Professor of Public Health. He leads the School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, Herbert Wertheim School of Public Health and Human Longevity Science, and UC San Diego Health. In this role, Dr. Carethers drives the overarching strategy for all of Health Sciences, working with campus and health system leadership to expand UC San Diego Health's clinical enterprise, foster research collaborations, enhance educational opportunities, and expand philanthropic participation. His leadership and collaborative approach continue to enhance the global prestige and distinction of the university's health sciences. A distinguished physician-scientist, Dr. Carethers specializes in gastroenterological research and treatment, with clinical and research interests including familial colon cancer syndromes, mechanisms of tumor progression, DNA mismatch repair, and colorectal cancer disparities. He joined UC San Diego in 2023 after a 13-year tenure at the University of Michigan, where he served as the C. Richard Boland Distinguished University Professor and the John G. Searle Professor and chair of the Department of Internal Medicine. Prior to that, he spent nearly 15 years at UC San Diego School of Medicine, including serving as chief of the Division of Gastroenterology, where…
Research topics
- Internal medicine
- Medicine
- Political Science
- Virology
- Sociology
- Environmental health
- Gerontology
- Oncology
- Pathology
- Demography
Selected publications
Approach Toward Early Detection and Prevention of Early-Onset Colorectal Cancer
Annual Review of Medicine · 2025-11-07 · 2 citations
articleOpen accessEarly-onset colorectal cancer (CRC), commonly defined as a CRC diagnosis before 50 years of age, is rapidly increasing. Despite overt symptoms, younger patients with early-onset CRC endure prolonged diagnostic delays. This review urgently delineates the clinical barriers hindering earlier detection by outlining the key steps in the diagnostic pathways, including how symptom recognition and early detection are complicated by patient- and provider-level barriers. We also reiterate challenges and o…
Cancer Prevention Research · 2025-06-02 · 2 citations
article1st authorCorrespondingCancer screening lowers morbidity and mortality from cancer and is cost-effective. The COVID-19 pandemic upended cancer screening utilization in 2020 with data showing a deficit in screened patients in 2020 and 2021 as compared with 2019, with return to 2019 baseline screening levels by December 2022. The cumulative shortfall in screenings, lasting nearly 3 years into the pandemic, is predicted by models to generate an incremental population cancer burden in the out-years of the models. Recovery…
Gastroenterology · 2026-05-01
articleTu1315 A TARGETED GENETIC ALTERATION ASSOCIATED WITH ALCOHOL CONSUMPTION IN COLON CANCER
Gastroenterology · 2026-05-01
articleSenior authorGastroenterology · 2026-05-01
articleSenior author
Recent grants
NIH · $1.1M · 2006
(PQ3) Immune Modulation of DNA Mismatch Repair in Colorectal Cancer
NIH · $1.8M · 2016–2021
NIH · $477k · 2000
Frequent coauthors
- 106 shared
Minoru Koi
University of California, San Diego
- 80 shared
Stephanie Tseng-Rogenski
University of Michigan–Ann Arbor
- 61 shared
Jan Tack
- 54 shared
Barbara Jung
University of Washington
- 50 shared
Temitope O. Keku
University of North Carolina at Chapel Hill
- 35 shared
C. Richard Boland
University of California, San Diego
- 35 shared
Heekyung Chung
- 31 shared
Moriya Iwaizumi
Hamamatsu University School of Medicine
Education
- 1989
M.D.
Wayne State University School of Medicine
B.S.
Wayne State University
- 1992
M.D., Internal Medicine
Massachusetts General Hospital
- 1995
M.D., Gastroenterology
University of Michigan
Awards & honors
- C. Richard Boland Distinguished University Professor
- John G. Searle Professor
- Inaugural National Institutes of Health-funded Gastroenterol…
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