Jianping Fu

About

Jianping Fu is a professor in the departments of Mechanical Engineering, Biomedical Engineering, and Cell and Developmental Biology at the University of Michigan. He holds a PhD from the Massachusetts Institute of Technology (2007) and a BE from the University of Science and Technology of China (2000). His research interests encompass stem cell bioengineering, developmental bioengineering, mechanobiology, and BioMEMS. Fu's work integrates emerging mechanobiology research with human pluripotent stem cells to study the fundamental roles of cell mechanics and mechanobiology in early human embryonic development. He has made significant contributions to understanding how mechanical signals influence human embryo development and has developed innovative techniques for creating human embryo-like structures from stem cells. Recognized for his achievements, Fu has received numerous awards, including the Friedrich Wilhelm Bessel Research Award, the Mid-career Biosciences Faculty Achievement Recognition Award, and fellowships in prestigious societies such as the AAAS, AIMBE, and BMES. He is also an elected member of the International Academy of Medical and Biological Engineers and serves on editorial boards of leading journals in his field.

Research topics

• Biotechnology
• Cell biology
• Engineering ethics
• Biology
• Computer Science
• Engineering

Selected publications

• ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

  Stem Cell Reports · 2021 · 343 citations

  The International Society for Stem Cell Research has updated its Guidelines for Stem Cell Research and Clinical Translation in order to address advances in stem cell science and other relevant fields, together with the associated ethical, social, and policy issues that have arisen since the last update in 2016. While growing to encompass the evolving science, clinical applications of stem cells, and the increasingly complex implications of stem cell research for society, the basic principles und…

  PublisherOA PDFDOI

• Stem-cell-based embryo models for fundamental research and translation

  Nature Materials · 2020-11-16 · 170 citations

  reviewOpen access1st authorCorresponding
  PublisherOA PDFDOI

• Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells

  Developmental Cell · 2020-11-17 · 146 citations

  articleOpen access
  PublisherOA PDFDOI

• Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines

  Stem Cell Reports · 2021 · 126 citations

  The ISSCR Guidelines for Stem Cell Research and Clinical Translation were last revised in 2016. Since then, rapid progress has been made in research areas related to in vitro culture of human embryos, creation of stem cell-based embryo models, and in vitro gametogenesis. Therefore, a working group of international experts was convened to review the oversight process and provide an update to the guidelines. This report captures the discussion and summarizes the major recommendations made by this…

  DOI

• A comprehensive human embryo reference tool using single-cell RNA-sequencing data

  Nature Methods · 2024-11-14 · 90 citations

  articleOpen access

  Stem cell-based embryo models offer unprecedented experimental tools for studying early human development. The usefulness of embryo models hinges on their molecular, cellular and structural fidelities to their in vivo counterparts. To authenticate human embryo models, single-cell RNA sequencing has been utilized for unbiased transcriptional profiling. However, an organized and integrated human single-cell RNA-sequencing dataset, serving as a universal reference for benchmarking human embryo mode…

  PublisherOA PDFDOI

Recent grants

• Studying Origin of Human Primordial Germ Cells Using a Synthetic Stem Cell Model

  NIH · $422k · 2020–2023

• Ultrasound-mediated Directed Osteogenic Differentiation of Mesenchymal Stem Cells

  NIH · $428k · 2014–2017

• CAREER: Biomechanical Phenotyping of Contractile Vascular Smooth Muscle Cells

  NSF · $449k · 2012–2017

Frequent coauthors

• Tao Zhang

  Zhejiang Academy of Medical Sciences

  57 shared

• Weiqiang Chen

  New York University

  49 shared

• Yubing Sun

  University of Massachusetts Amherst

  38 shared

• Xufeng Xue

  Institute of Acoustics

  37 shared

• Yue Shao

  Tsinghua University

  37 shared

• Yi Zheng

  Southern Medical University

  37 shared

• Peng Peng

  Yuhuangding Hospital

  33 shared

• Raymond H. W. Lam

  City University of New York

  31 shared

Labs

• Jianping Fu's GroupPI

Education

• Ph.D., Mechanical Engineering

  Massachusetts Institute of Technology

  2007

• B.E., Mechanical Engineering

  University of Science and Technology of China

  2000

Similar researchers at University of Michigan

• Brent Gillespieh-102
• Wei Luh-98
• Pramod Sangi Reddyh-79