Jianghong Meng
· Professor, Director of Center for Food Safety and Security Systems (CFS3), and Director of the Joint Institute for Food Safety & Applied Nutrition (JIFSAN)University of Maryland, College Park · Nutrition and Food Studies
Active 1994–2026
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About
Jianghong Meng is a Professor in the Department of Nutrition & Food Science at the University of Maryland, College Park. His research focuses on food safety microbiology, specifically molecular identification, antimicrobial resistance, and pathogenicity of major foodborne pathogens including Shiga toxin-producing Escherichia coli, Campylobacter, Salmonella, and Listeria monocytogenes. Dr. Meng holds a Ph.D. in Comparative Pathology from the University of California, Davis, a Master of Preventive Veterinary Medicine from UC Davis, and a DVM from Sichuan Agricultural University in China. He serves as the Director of the Center for Food Safety and Security Systems and the Joint Institute for Food Safety & Applied Nutrition. Dr. Meng has received numerous awards and honors, including Fellowships in the American Academy of Microbiology and the International Association for Food Protection, as well as awards from the US Food & Drug Administration and the USDA. His professional service includes participation in various national and international committees and panels related to food safety microbiology, antibiotic resistance, and public health data. His contributions significantly advance understanding in food safety microbiology, antimicrobial resistance, and pathogen detection.
Research topics
- Genetics
- Computational biology
- Biology
- Materials science
- Nanotechnology
Selected publications
BMC Genomics · 2020 · 99 citations
Senior authorCorrespondingBACKGROUND: We benchmarked the hybrid assembly approaches of MaSuRCA, SPAdes, and Unicycler for bacterial pathogens using Illumina and Oxford Nanopore sequencing by determining genome completeness and accuracy, antimicrobial resistance (AMR), virulence potential, multilocus sequence typing (MLST), phylogeny, and pan genome. Ten bacterial species (10 strains) were tested for simulated reads of both mediocre- and low-quality, whereas 11 bacterial species (12 strains) were tested for real reads. RE…
Genomics · 2021 · 64 citations
Senior authorCorrespondingOxford Nanopore sequencing has been widely used to achieve complete genomes of bacterial pathogens. However, the error rates of Oxford Nanopore long reads are high. Various polishing algorithms using Illumina short reads to correct the errors in Oxford Nanopore long-read assemblies have been developed. The impact of polishing the Oxford Nanopore long-read assemblies of bacterial pathogens with Illumina short reads on improving genomic analyses was evaluated using both simulated and real reads. T…
iMeta · 2024-04-27 · 24 citations
articleOpen accessAkkermansia muciniphila pretreatment mitigated Listeria monocytogenes infection in mice. A. muciniphila improved gut microbiota disturbed by L. monocytogenes infection and significantly increased the level of intestinal linoleic acid in mice. Linoleic acid strengthened the intestinal epithelial barrier and reduced pathogen translocation partly by regulating NF-κB/MLCK pathway in a GPR40-dependent manner. Listeria monocytogenes is a Gram-positive bacterium that causes infections in humans ranging…
mBio · 2024-06-26 · 22 citations
articleOpen accessABSTRACT This study examined the diversity and persistence of Salmonella in the surface waters of agricultural regions of Brazil, Chile, and Mexico. Research groups (three in 2019–2020 and five in 2021–2022) conducted a long-term survey of surface water across 5–8 months annually ( n = 30 monthly). On-site, each team filtered 10-L water samples with modified Moore Swabs to capture Salmonella, which were then isolated and identified using conventional microbiological techniques. Salmonella isolat…
Microbiology Spectrum · 2024-04-30 · 14 citations
articleOpen accessSenior authorABSTRACT Oxford Nanopore sequencing is one of the high-throughput sequencing technologies that facilitates the reconstruction of metagenome-assembled genomes (MAGs). This study aimed to assess the potential of long-read assembly algorithms in Oxford Nanopore sequencing to enhance the MAG-based identification of bacterial pathogens using both simulated and mock communities. Simulated communities were generated to mimic those on fresh spinach and in surface water. Long reads were produced using R9…
Recent grants
Frequent coauthors
- 172 shared
Shaohua Zhao
United States Food and Drug Administration
- 144 shared
Eric W. Brown
Society for Healthcare Epidemiology of America
- 103 shared
Marc W. Allard
Center for Food Safety and Applied Nutrition
- 99 shared
Patrick F. McDermott
United States Food and Drug Administration
- 79 shared
Guojie Cao
Center for Food Safety and Applied Nutrition
- 72 shared
Xuebin Xu
Xinjiang University
- 66 shared
Zhao Chen
Center for Food Safety and Applied Nutrition
- 66 shared
Dai Kuang
Ruijin Hospital
Awards & honors
- Fellow, American Academy of Microbiology
- Fellow, International Association for Food Protection
- Commissioner’s Special Citation Award, the US Food & Drug Ad…
- Outstanding Service Award, the National Advisory Committee o…
- FDA/CFSAN Director’s Special Citation Award on Aquacultural…
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