Jeffrey Moffitt
· Associate ProfessorHarvard University · Strategy
Active 2000–2026
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About
Dr. Jeffrey Moffitt is an Associate Professor at Boston Children's Hospital and Harvard Medical School. His research focuses on the development and application of advanced imaging and molecular techniques to understand cellular and molecular mechanisms. His work involves exploring the intricacies of biological systems through innovative approaches, contributing significantly to the fields of cellular and molecular biology.
Research topics
- Computer Science
- Biology
- Computational biology
- Genetics
- Artificial Intelligence
- Anatomy
- Cell biology
- Bioinformatics
- Computer vision
- Cancer research
Selected publications
MAFG-driven astrocytes promote CNS inflammation
Nature · 2020 · 497 citations
The emerging landscape of spatial profiling technologies
Nature Reviews Genetics · 2022 · 412 citations
1st authorCorrespondingCell segmentation in imaging-based spatial transcriptomics
Nature Biotechnology · 2021 · 408 citations
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
Nature Cell Biology · 2023 · 170 citations
Highly multiplexed spatial transcriptomics in bacteria
Science · 2025-01-23 · 76 citations
articleOpen accessSenior authorCorrespondingSingle-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hindered by the massive density of bacterial messenger RNA. To overcome this challenge, we combined 1000-fold volumetric expansion with multiplexed error-robust fluorescence in situ hybridization (MERFISH) to create bacterial-MERFISH. This method enables high-throughput, spatially resolved profiling of…
Frequent coauthors
- 75 shared
Xiaowei Zhuang
Harvard University Press
- 55 shared
Carlos Bustamante
University of California, Berkeley
- 54 shared
Rosalind J. Xu
Boston Children's Museum
- 37 shared
Brianna R. Watson
Harvard University
- 36 shared
Roni Nowarski
Brigham and Women's Hospital
- 29 shared
Francisco J. Quintana
Harvard University
- 28 shared
Ana C. Anderson
Brigham and Women's Hospital
- 28 shared
Kisha N. Sivanathan
Brigham and Women's Hospital
Labs
Not provided
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