Jean Crowell Beckham

About

Jean Crowell Beckham is a Professor in the Department of Psychiatry and Behavioral Sciences at Duke University. She serves as the Co-Division Director of Behavioral Medicine and Neurosciences within the department. Her role involves leadership in clinical and research initiatives related to behavioral medicine and neuroscience, contributing to the academic and clinical missions of Duke University. Her contact information is provided through her email beckham@duke.edu, and her office is located at Box 3625, Durham, NC 27710.

Research topics

• Medicine
• Biology
• Genetics
• Internal medicine
• Psychology
• Clinical psychology
• Computational biology
• Bioinformatics
• Psychiatry
• Computer Science

Selected publications

• The genetic architecture of the human cerebral cortex

  Science · 2020 · 871 citations

  The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci a…

  DOI

• Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

  Nature Genetics · 2020 · 787 citations

  DOI

• Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19

  Nature Medicine · 2021 · 245 citations

  DOI

• Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

  Biological Psychiatry · 2021 · 240 citations

  DOI

• Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

  Circulation · 2020 · 142 citations

  BACKGROUND: Abdominal aortic aneurysm (AAA) is an important cause of cardiovascular mortality; however, its genetic determinants remain incompletely defined. In total, 10 previously identified risk loci explain a small fraction of AAA heritability. METHODS: We performed a genome-wide association study in the Million Veteran Program testing ≈18 million DNA sequence variants with AAA (7642 cases and 172 172 controls) in veterans of European ancestry with independent replication in up to 4972 cases…

  DOI

Recent grants

• NIH Grant R29MH051752

  NIH · $462k · 2000

• NIH Grant I01RX001301

  NIH · 2019

• NIH Grant K24DA016388

  NIH · $1.6M · 2014

Frequent coauthors

• Patrick S. Calhoun

  Duke University

  1678 shared

• Nathan A. Kimbrel

  Duke University

  906 shared

• Michelle F. Dennis

  669 shared

• Eric A. Dedert

  Health Services Research & Development

  522 shared

• Paul A. Dennis

  Durham VA Health Care System

  413 shared

• Eric B. Elbogen

  Duke University

  388 shared

• Elizabeth E. Van Voorhees

  Duke University

  343 shared

• Henry R. Wagner

  Duke Medical Center

  289 shared

Similar researchers at Duke University

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• Melanie Jean Bonnerh-57
• Ravi Anandh-45