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Jay F. Levine

Jay F. Levine

Verified

North Carolina State University · Fisheries, Wildlife, and Conservation Biology

Active 1932–2025

h-index59
Citations12.2k
Papers2397 last 5y
Funding
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About

Dr. Jay Levine is a Professor of Epidemiology and Public Health who joined NC State in 1984. His research work spans more than three decades and initially focused on arthropod-borne diseases, particularly Lyme disease. He has coordinated studies on marine bivalves and shellfish safety, marine finfish, veterinary health problems in companion animals, and ecosystem health. His Aquatic Epidemiology and Conservation Laboratory focuses on some of the most imperiled animals on the planet, including freshwater mussels and snails. Dr. Levine, along with his staff and students, works to enhance understanding of these freshwater invertebrates, develop new diagnostic techniques for studying their health, and refine methods that support their conservation and captive propagation for population augmentation. Additional research includes identifying vertebrate sources of fecal waste in surface waters. Beyond his research, Dr. Levine is actively engaged in NC communities, supporting initiatives related to environmental restoration, stormwater mitigation, and early childhood literacy. Since 2009, he has coordinated the Homework Haven program, a free after-school tutoring initiative in South Raleigh.

Research topics

  • Biology
  • Computer Science
  • Materials science
  • Nanotechnology
  • Pathology
  • Engineering
  • Genetics
  • Immunology
  • Electrical engineering
  • Environmental health
  • Medicine
  • Virology
  • Veterinary medicine
  • Molecular biology
  • Computational biology
  • Ecology

Selected publications

  • BOARD #130: AI-Driven Mussel Behavior Monitoring Using An Accessible 3D Imaging System

    2025-08-21

    article
  • Political identity as a driver of hunter responses to chronic wasting disease in a post-COVID world

    Human Dimensions of Wildlife · 2024-11-06 · 2 citations

    article
  • Predicting residential septic system malfunctions for targeted drone inspections

    Remote Sensing Applications Society and Environment · 2023-02-15 · 5 citations

    article
  • Developing mitochondrial DNA field-compatible tests

    Critical Reviews in Environmental Science and Technology · 2021 · 4 citations

    Senior authorCorresponding
    • Computational biology
    • Biology
    • Molecular biology

    Nucleic acid-based molecular detection of mitochondrial DNA (mtDNA) has been used for the detection of eukaryotic pathogens, genetic markers, and biomedical studies in humans and animals, forensic investigation, conservation biology, and environmental monitoring. Currently available molecular mtDNA testing is predominately dependent on relatively expensive laboratory equipment, which limits test applicability for on-site field testing. Recent technical advances in molecular testing of mtDNA using microfluidic chip technology and paper-based methods, and assays based on isothermal nucleic acid amplification show promise for field assay development. Microfluidic and paper-based components for mtDNA sample preparation and isothermal amplification establish the groundwork for targeted detection. The goal is on-site field detection mtDNA assays that combine sample processing, assay setup, and visual representation of the presence of mtDNA. This review examines advantages and disadvantages of alternative field-compatible tests for on-site detection of mtDNA. Despite challenges, developing an integrated “sample-through detection” field test platform is the future direction for mtDNA molecular detection in environmental samples.

  • Farmer Cooperatives "Take Cover": The Capper-Volstead Exemption is Under Siege

    Arkansas law review · 2021-04-23

    articleOpen accessSenior author

    "When tillage begins, other arts follow. The farmers, therefore, are the founders of human civilization." There can be little dispute that food production is of vital interest to any nation’s security and economy. For this reason, the United States Congress, like many other legislatures around the world, has accorded special treatment to the agricultural industry, and particularly to farmers. One example of this special treatment is the Capper-Volstead Act, which provides farmers with immunity from antitrust liability for joint conduct undertaken by and through an “association” of producers.

  • BIVALVES

    2021-12-31

    other1st authorCorresponding

    Bivalves are increasingly being included as display animals in homes and public aquaria, and as invertebrate alternatives for biomedical research studies. This chapter is an introduction to their basic anatomy and physiology, their maintenance requirements, and standard aquaculture techniques. It provides detailed descriptions of economically relevant bivalve pathogens as examples of the types of problems that may affect bivalve health in both closed recirculating and open systems. Hemolymph cell and biochemical composition play a key role in bivalve health assessments. Bivalves provide a lengthy list of ecosystem services. The culture of bivalves for human consumption is a global enterprise. Oysters, clams, scallops, and other species are actively cultured for local, regional, and global food markets. Although the specific growth requirements of individual species vary, three universal basic requirements drive the effective selection of rearing locations: water quality, physical and chemical conditions that define the rearing site, and adequate diet.

  • An Accelerometer-Based Sensing System to Study the Valve-Gaping Behavior of Bivalves

    IEEE Sensors Letters · 2021 · 11 citations

    • Computer Science
    • Computer Science
    • Engineering

    Bivalves are extremely sensitive to environmental conditions. The movement of their shells and the gap in-between the valves can serve as indicators of water pollutants entering surface water bodies. This letter proposes a novel sensing system to accurately calculate the valve-gaping angle in bivalves. The sensor unit is comprised of two inertial measurement units for each bivalve to estimate the angle between the two valves. Monitoring of multiple bivalves is possible with several water-insulated sensor units tethered with flexible cables to a central base station housing the processing unit. Miniaturization of the sensor packaging and flexibility of the wires ensured minimum hindrance to the animals' natural behavior. The precision and accuracy of the angle measurement were tested with a benchtop servo motor setup simulating the gaping behavior. The standard deviation of measurements at a steady state was 0.78 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> , and the average change in measurement during a 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> step was 9.98 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> . Over 250 h of in vivo validation experiments demonstrated the consistency of the angle measurements using the presented method alongside a magnetic alternative, which had an average correlation coefficient of $-$0.89. The sensor system provides an accurate study of bivalve gaping behavior and facilitates the potential use of bivalves as environmental sentinels due to their valve-gaping being a biomarker for monitoring water pollution.

  • Le syndrome ADNP (protéine neuroprotectrice dépendante de l’activité) lié à la déficience intellectuelle et aux troubles du spectre autistique : une revue de la littérature

    Neuropsychiatrie de l Enfance et de l Adolescence · 2020-01-31

    articleOpen access
  • Frequency of Animal Leptospirosis in the Southern United States and the Implications for Human Health

    Southern Medical Journal · 2020 · 7 citations

    Senior authorCorresponding
    • Medicine
    • Environmental health
    • Veterinary medicine

    spp detection in animals in wild habitats increased slightly over time (<0.2%/year). We identified reports of 11 human leptospirosis illness clusters and outbreaks in the southern United States. Exposure to potentially contaminated surface waters were documented for at least seven of the events, and interactions with infected or likely infected animals were documented for at least six of the events. This analysis highlights the need for stronger partnerships across the public and animal health fields to enhance diagnostics, surveillance, and reporting. The early identification of leptospirosis in animals may serve as an indicator of environmental contamination and trigger prevention measures, such as vaccinating companion animals and livestock, use of potable water, and the wearing of waterproof protective clothing near water that may be contaminated.

  • Synthesis of isobemisiose, neosartose, and fischerose: three α-1,6-linked trehalose-based oligosaccharides identified from <i>Neosartorya fischeri</i>

    RSC Advances · 2020-01-01 · 1 citations

    articleOpen access

    Herein, we report the first concise, scalable, and iterative chemical synthesis of these oligosaccharides from a differentially protected thioglycoside donor and a selectively protected, asymmetric trehalose acceptor. This work constitutes an improved synthesis of isobemisiose, and is also the first reported synthesis of neosartose, a tetrasaccharide, and fischerose, a pentasaccharide, in good yield. Importantly, in-depth studies of biological function are enabled by this synthetic platform.

Frequent coauthors

  • J. H. Kim

    Cancer Center Amsterdam

    48 shared
  • M. Grotzer

    30 shared
  • L. Giunti

    Amsterdam UMC Location VUmc

    30 shared
  • E. Hulleman

    30 shared
  • T. Shalaby

    University of North Carolina at Chapel Hill

    30 shared
  • L. Genitori

    Cancer Center Amsterdam

    30 shared
  • Michael K. Stoskopf

    North Carolina State University

    30 shared
  • Dannis G. van Vuurden

    University Hospital of Geneva

    30 shared

Labs

Education

  • Ph.D., Atmospheric Chemistry

    University of California, Santa Barbara

    1990
  • M.S., Atmospheric Chemistry

    University of California, Santa Barbara

    1986
  • B.S., Chemistry

    University of California, Santa Barbara

    1983
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