Jae-Hyun Chung

About

Jae-Hyun Chung is a Professor of Mechanical Engineering at the University of Washington. His research areas include engineering and health, engineering and manufacturing, mechanics of materials, biomechanics, and advanced materials. His work focuses on these interdisciplinary fields, contributing to the development of innovative solutions in biomechanics and materials science, and advancing understanding in engineering applications related to health and manufacturing.

Research topics

• Materials science
• Nanotechnology
• Chemistry
• Chromatography
• Microbiology

Selected publications

• Single Walled Carbon Nanotube-Based Junction Biosensor for Detection of Escherichia coli

  PLoS ONE · 2014-09-18 · 71 citations

  articleOpen access

  Foodborne pathogen detection using biomolecules and nanomaterials may lead to platforms for rapid and simple electronic biosensing. Integration of single walled carbon nanotubes (SWCNTs) and immobilized antibodies into a disposable bio-nano combinatorial junction sensor was fabricated for detection of Escherichia coli K-12. Gold tungsten wires (50 µm diameter) coated with polyethylenimine (PEI) and SWCNTs were aligned to form a crossbar junction, which was functionalized with streptavidin and bi…

  PublisherOA PDFDOI

• Immunosensor towards low-cost, rapid diagnosis of tuberculosis

  Lab on a Chip · 2012-01-01 · 56 citations

  articleSenior author

  A rapid, accurate tuberculosis diagnostic tool that is compatible with the needs of tuberculosis-endemic settings is a long-sought goal. An immunofluorescence microtip sensor is described that detects Mycobacterium tuberculosis complex cells in sputum in 25 minutes. Concentration mechanisms based on flow circulation and electric field are combined at different scales to concentrate target bacteria in 1 mL samples onto the surfaces of microscale tips. Specificity is conferred by genus-specific an…

  PublisherDOI

• USNCTAM perspectives on mechanics in medicine

  Journal of The Royal Society Interface · 2014-05-28 · 44 citations

  articleOpen access

  Over decades, the theoretical and applied mechanics community has developed sophisticated approaches for analysing the behaviour of complex engineering systems. Most of these approaches have targeted systems in the transportation, materials, defence and energy industries. Applying and further developing engineering approaches for understanding, predicting and modulating the response of complicated biomedical processes not only holds great promise in meeting societal needs, but also poses serious…

  PublisherOA PDFDOI

• Microfluidic one-step synthesis of alginate microspheres immobilized with antibodies

  Journal of The Royal Society Interface · 2013-08-21 · 37 citations

  articleOpen access

  Micrometre- and submicrometre-size functionalized beads are frequently used to capture targets of interest from a biological sample for biological characterizations and disease diagnosis. The main challenge of the microbead-based assay is in the immobilization of probe molecules onto the microbead surfaces. In this paper, we report a versatile droplet microfluidics method to fabricate alginate microspheres while simultaneously immobilizing anti-Mycobacterium tuberculosis complex IgY and anti-Esc…

  PublisherOA PDFDOI

• Cryopreservation of Mycobacterium tuberculosis Complex Cells

  Journal of Clinical Microbiology · 2012-08-30 · 35 citations

  articleOpen access

  Successful long-term preservation of Mycobacterium tuberculosis cells is important for sample transport, research, biobanking, and the development of new drugs, vaccines, biomarkers, and diagnostics. In this report, Mycobacterium bovis bacillus Calmette-Guérin and M. tuberculosis H37Ra were used as models of M. tuberculosis complex strains to study cryopreservation of M. tuberculosis complex cells in diverse sample matrices at different cooling rates. Cells were cryopreserved in diverse sample m…

  PublisherOA PDFDOI

Recent grants

• CAREER: Nano-Tip Sensor for Rapid Detection of Dissolved DNA for Environmental Monitoring

  NSF · $400k · 2009–2014

• NIH Grant R43GM099347

  NIH · $150k · 2013

Frequent coauthors

• Kyong-Hoon Lee

  34 shared

• Kieseok Oh

  Kobe City Medical Center West Hospital

  22 shared

• Woon‐Hong Yeo

  Georgia Institute of Technology

  22 shared

• Yaling Liu

  Lehigh University

  21 shared

• Jong‐Hoon Kim

  21 shared

• Wing Kam Liu

  19 shared

• Gerard A. Cangelosi

  University of Washington

  14 shared

• James J. Riley

  13 shared

Awards & honors

• NSF CAREER Award
• McMinn Endowed Professorship
• Samsung Electronics Humantech Thesis Award

Similar researchers at University of Washington

• Steve Bruntonh-74
• Michael Baileyh-68
• Alberto Alisedah-29