Itty Abraham

About

Itty Abraham is a faculty member at Arizona State University's School for the Future of Innovation in Society. His scholarship explores the intersections of technology, law, and society with a focus on postcolonial contexts and global perspectives. His work critically examines the colonial roots and international dimensions of legal and technological systems, such as the UN Refugee Convention and India's biometric identification project, Aadhaar. Abraham's research extends to the politics of forced migration, diasporic activism, and the role of digital technologies in political recognition, as exemplified by his studies on the Rohingya community's use of online platforms to contest state authority. He also contributes to science and technology studies (STS) by advocating for a global frame that challenges traditional East-West dichotomies and incorporates concepts like hybridity, violence, and impermanence. Through historical and aspirational analyses, Abraham interrogates how technology and law shape modern social and political power, emphasizing the experiences and voices of newly independent states and marginalized communities in international order and global knowledge production.

Research topics

• Biology
• Medicine
• Computer Science
• Chemistry
• Environmental health
• Toxicology
• Waste management
• Genetics
• Engineering
• Ecology

Selected publications

• Noncancer Risk Assessment: Principles and Practice in Environmental and Occupational Settings

  Patty's Toxicology · 2012-08-17 · 18 citations

  other

  Abstract The approach to assessing the risks of noncancer toxicity has differed historically from that used to assess the potential risks of carcinogenicity. Assessment of risks of carcinogenicity has historically assumed that a small number of molecular events can evoke mutagenic changes in a single cell, ultimately leading to self‐replicating damage and carcinogenicity. Generally, this is considered a nonthreshold effect because presumably all levels of exposure may pose a small, but finite, p…

  PublisherDOI

• Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link:  Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link † , ‡

  Figshare · 2020-10-31 · 1 citations

  articleOpen access

  Proteins that discriminate between cisplatin–DNA adducts and oxaliplatin–DNA adducts are thought to be responsible for the differences in tumor range, toxicity, and mutagenicity of these two important chemotherapeutic agents. However, the structural basis for differential protein recognition of these adducts has not been determined and could be important for the design of more effective platinum anticancer agents. We have determined high-resolution NMR structures for cisplatin–GG and undamaged D…

  PublisherOA PDFDOI

• Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links

  UNC Libraries · 2020-11-07

  articleOpen access

  The differences in efficacy and molecular mechanisms of platinum anti-cancer drugs cisplatin (CP) and oxaliplatin (OX) are thought to be partially due to the differences in the DNA conformations of the CP and OX adducts that form on adjacent guanines on DNA, which in turn influence the binding of damage-recognition proteins that control downstream effects of the adducts. Here we report a comprehensive comparison of the structural distortion of DNA caused by CP and OX adducts in the TGGT sequence…

  PublisherDOI

• Pelizaeus Merzbacher disease: morphological analysis of the vestibulo-cochlear system

  Acta Oto-Laryngologica · 2009-01-01

  article
  PublisherDOI

Frequent coauthors

• Michael M. Gottesman

  National Cancer Institute

  38 shared

• Martin D. Chapman

  20 shared

• Carolyn D. Whitfield

  Clinical Research Organization

  17 shared

• Dana P. Ascherman

  University of Pittsburgh

  17 shared

• Jacob Hochman

  Hebrew University of Jerusalem

  16 shared

• T J Singh

  16 shared

• M M Gottesman

  National Cancer Institute

  16 shared

• Ira Pastan

  16 shared

Labs

• Arizona State University, School for the Future of Innovation in SocietyPI

Education

• B.A., Economics

  Loyola College, Madras

• Ph.D., Political Science

  University of Illinois, Urbana-Champaign

Awards & honors

• Senior Fulbright-Nehru Scholar (2011)
• Awards and grants from the National Science Foundation
• Awards and grants from US Institute of Peace
• Awards and grants from Ford Foundation
• Awards and grants from MacArthur Foundation

Similar researchers at Arizona State University

• Andrew Maynardh-51
• David Gustonh-36
• Erik Fisherh-25