Research topics
- Medicine
- Urology
- Internal medicine
- Intensive care medicine
- Gynecology
- Physical therapy
- Neuroscience
- Biology
- Pathology
Selected publications
Financial Cost of Genitourinary Foreign Objects: A Single-Institution Experience
Urology · 2025-03-08 · 1 citations
articleSenior authorMP27-19 IMPROVING ANTIBIOTIC STEWARDSHIP IN PATIENTS UNDERGOING URODYNAMIC TESTING
The Journal of Urology · 2025-04-08
articleSenior authorManaging Neurogenic Bladder with a Suprapubic Catheter vs Urethral Foley – Which is Best?
Current Bladder Dysfunction Reports · 2025-04-28
articleSenior authorCancers · 2024-06-20
articleOpen accessSenior authorCorrespondingHuman papillomavirus (HPV) has been implicated in various cancers, including those affecting the skin. The study assessed the long-term risk of skin cancer associated with HPV infection in Taiwan region, using data from the National Health Insurance Research Database between 2007 and 2015. Our analysis revealed a significant increase in skin cancer risk among those with HPV, particularly for squamous cell carcinoma (SCC), the subtype with the highest observed adjusted hazard ratio (aHR) = 5.97, 95% CI: 4.96-7.19). The overall aHR for HPV-related skin cancer was 5.22 (95% CI: 4.70-5.80), indicating a notably higher risk in the HPV-positive group. The risk of skin cancer was further stratified by type, with basal cell carcinoma (aHR = 4.88, 95% CI: 4.14-5.74), and melanoma (aHR = 4.36, 95% CI: 2.76-6.89) also showing significant associations with HPV. The study also highlighted regional variations, with increased risks in southern Taiwan and the Kaohsiung-Pingtung area. Key findings emphasize the importance of sun protection, particularly in regions of high UV exposure and among individuals in high-risk occupations. This research contributes to a better understanding of the complex interactions between HPV and skin cancer risk, reinforcing the importance of preventive strategies in public health.
To mesh or not mesh “apical prolapse,” that is the question!
Neurourology and Urodynamics · 2024-04-16 · 4 citations
reviewOpen access1st authorCorrespondingAIMS: The management of pelvic organ prolapse (POP) involves both nonsurgical and surgical management. Views on best surgical approach for apical prolapse is an evolving field based on recent evidence and events related to transvaginal mesh. METHODS: At the 97th Annual Meeting of the North Central Section of the American Urological Association (Scottsdale, AZ, USA), this topic was discussed and debated. The following article summarizes the concepts presented that day as well as the interactive debate with three perspectives on apical prolapse surgeries. The authors were asked to support their approach in various scenarios including: extremes of age, prior hysterectomy and intact uterus, desire to avoid mesh, sexual activity, and presence of comorbidities. RESULTS: Surgical approaches for POP have evolved and is a popular topic for debate, particularly when discussing apical prolapse. Transvaginal native tissue repairs remain the mainstay of POP surgeries; however, transabdominal approaches continue to evolve. Use of interposition material, such as synthetic polypropylene mesh, is the standard when performing an abdominal sacrocolpopexy, however, use of autologous fascia can be considered. Small series have demonstrated the safety and efficacy of autologous fascia-based repairs; however, larger studies with longer follow-up are needed. CONCLUSIONS: There are a variety of surgical strategies to repair POP. Ultimate decision making on specific surgeries should be determined by patient preference and goals after appropriate counseling on all options.
Recently Described Innovative Reconstruction in Neurogenic Bladder: a Review
Current Bladder Dysfunction Reports · 2022
Senior authorCorresponding- Medicine
- Urology
- Neuroscience
Neurourology and Urodynamics · 2021 · 2 citations
- Medicine
- Urology
- Internal medicine
INTRODUCTION/BACKGROUND: Sensation of incomplete bladder emptying (SIBE) has been shown to be correlated with an elevated post-void residual (PVR) in men, however, the significance of this symptom and whether it correlates with an elevated PVR in women is less clear. In this study, we assessed if SIBE in women is correlated with an elevated PVR and determined the relationship of SIBE to other lower urinary tract symptoms. METHODS/MATERIALS: Women ages ≥18 with lower urinary tract symptoms were eligible. SIBE was defined by a response "sometimes", "most of the time", or "all of the time" to the question "How often do you feel that your bladder has not emptied properly after you have urinated?" on the International Consultation on Incontinence Questionnaire. Frequency and bother of other lower urinary tract symptoms were also assessed to compare their relationship to SIBE. Elevated PVR was defined as ≥100 ml via ultrasound. RESULTS: We prospectively evaluated 95 women, 59% of whom reported SIBE. Compared to women without SIBE, women with SIBE reported more urinary hesitancy (51% vs. 18%, p = 0.002), intermittency (56% vs. 16%, p < 0.001), weak stream (36% vs. 5%, p < 0.001), dysuria (29% vs. 5%, p = 0.004), and straining (25% vs 5%, p = 0.013). However, there was no difference in elevated PVRs between women with and without SIBE [5/56, 9% vs. 4/39, 10%, (p = 0.99)]. All women, regardless of SIBE, reported higher bother from storage and incontinence symptoms versus voiding symptoms with no difference in overall bother scores. CONCLUSION: SIBE is a common complaint in women with lower urinary tract symptoms. While women with SIBE reported more voiding symptoms, they were more bothered by storage symptoms. Importantly, most of these women emptied their bladder well and were not more likely to have an elevated PVR than women without SIBE.
The Role of Urodynamic Testing Prior to Third-Line OAB Therapy
Current Bladder Dysfunction Reports · 2020 · 1 citations
1st authorCorresponding- Medicine
- Intensive care medicine
- Physical therapy
Evaluation of Neurogenic Lower Urinary Tract Dysfunction
2020-10-16
book-chapter1st authorCorrespondingThe evaluation of patients suspected of having neurogenic lower urinary tract dysfunction (NLUTD) has two goals: first, to elucidate the process resulting in signs or symptoms of dysfunction, and second, to determine if the upper and lower urinary tracts are at risk for damage. NLUTD can be classified under the following rubrics: “failure to store”, “failure to empty”, or a combination of both. Patients with NLUTD can further be classified as at risk or not at risk for upper urinary tract damage/decompensation. In certain scenarios of NLUTD, serious urinary tract and/or renal function damage can result in the absence of symptoms. This chapter focuses on the use of urodynamic study (UDS) in general. The goals of UDS in patients with neurologic bladder dysfunction are to correlate patient symptoms with urodynamic events. The urodynamic evaluation consists of several components including cystometrogram, abdominal pressure monitoring, electromyography, uroflowmetry, and voiding pressure-flow studies.
Paratesticular Solitary Fibrous Tumor Masquerading as Metastatic Prostate Cancer
Applied Radiology · 2020-11-01
articleOpen access1st authorCorresponding
Frequent coauthors
- 9 shared
Joel D. A. Tyndall
University of Otago
- 9 shared
Qian Wu
Sun Yat-sen University
- 9 shared
Jennifer L. Martin
- 9 shared
Gary L. Grunewald
University of Kansas
- 9 shared
Michael J. McLeish
Indiana University – Purdue University Indianapolis
- 9 shared
Christine L. Gee
Howard Hughes Medical Institute
- 7 shared
Christian O. Twiss
University of Arizona
- 7 shared
Ming‐Fong Lin
University of Nebraska Medical Center
Education
- 2013
M.D., Medicine
University of Nebraska College of Medicine
- 2006
M.S., Engineering Biotechnology
University of Pennsylvania
- 2004
B.A., Molecular Biology
University of Pennsylvania
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