Optical imaging and spectroscopy for the study of the human brain: status report

Neurophotonics · 2022 · 171 citations

• Computer Science
• Data science
• Artificial Intelligence

This report is the second part of a comprehensive two-part series aimed at reviewing an extensive and diverse toolkit of novel methods to explore brain health and function. While the first report focused on neurophotonic tools mostly applicable to animal studies, here, we highlight optical spectroscopy and imaging methods relevant to noninvasive human brain studies. We outline current state-of-the-art technologies and software advances, explore the most recent impact of these technologies on neuroscience and clinical applications, identify the areas where innovation is needed, and provide an outlook for the future directions.

Neurophotonic Tools for Microscopic Measurements and Manipulation: Status Report

Neurophotonics · 2022 · 44 citations

• Computer Science
• Data science
• Computer Science

' agenda has been well aligned with this focus on neurotechnologies featuring new optical methods and tools applicable to brain studies. While the BRAIN Initiative 2.0 is pivoting towards applications of these novel tools in the quest to understand the brain, this status report reviews an extensive and diverse toolkit of novel methods to explore brain function that have emerged from the BRAIN Initiative and related large-scale efforts for measurement and manipulation of brain structure and function. Here, we focus on neurophotonic tools mostly applicable to animal studies. A companion report, scheduled to appear later this year, will cover diffuse optical imaging methods applicable to noninvasive human studies. For each domain, we outline the current state-of-the-art of the respective technologies, identify the areas where innovation is needed, and provide an outlook for the future directions.

Discovery and clinical translation of novel glaucoma biomarkers

Progress in Retinal and Eye Research · 2020 · 102 citations

• Medicine
• Intensive care medicine
• Bioinformatics