Eve Van Cauter

About

Eve Van Cauter is an Emeritus/Emerita Professor at the University of Chicago in the Department of Medicine-Endocrinology. Her research activities focus on sleep, circadian rhythms, and their impact on metabolic and cardiometabolic health. She has conducted extensive studies on how sleep disturbances, circadian misalignment, and sleep loss influence glucose regulation, insulin resistance, obesity, and cardiovascular risk. Her work includes investigating the biological mechanisms underlying these associations and exploring potential interventions such as pharmacologic treatments and light exposure to improve health outcomes. Van Cauter has contributed significantly to understanding the role of sleep and circadian biology in endocrine and metabolic processes, with numerous publications in the field.

Research topics

• Medicine
• Computer Science
• Endocrinology
• Internal medicine
• Psychology
• Neuroscience
• Biology
• Physiology
• Ophthalmology

Selected publications

• Health consequences of circadian disruption

  SLEEP · 2020 · 72 citations

  DOI

• A meta-analysis of the associations between insufficient sleep duration and antibody response to vaccination

  Current Biology · 2023-03-01 · 49 citations

  reviewOpen accessSenior author
  PublisherOA PDFDOI

• Sleep and circadian rhythms: pillars of health—a Keystone Symposia report

  Annals of the New York Academy of Sciences · 2021 · 47 citations

  The human circadian system consists of the master clock in the suprachiasmatic nuclei of the hypothalamus as well as in peripheral molecular clocks located in organs throughout the body. This system plays a major role in the temporal organization of biological and physiological processes, such as body temperature, blood pressure, hormone secretion, gene expression, and immune functions, which all manifest consistent diurnal patterns. Many facets of modern life, such as work schedules, travel, an…

  PublisherOA PDFDOI

• OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function

  Diabetes Care · 2021 · 43 citations

  OBJECTIVE: < 0.005) but not IIn. At month 12, the change in glucose response curves did not differ between youth and adults, and there was no treatment effect.CONCLUSIONSDespite a twofold higher prevalence of the more favorable BPh curve in youth at randomization, RISE interventions did not result in beneficial changes in glucose response curves in youth compared with adults. Moreover, the typical β-cell hypersecretion in youth was not present in the IIn curve, emphasizing the severity of β-cell…

  PublisherOA PDFDOI

• Hyperglucagonemia Does Not Explain the β-Cell Hyperresponsiveness and Insulin Resistance in Dysglycemic Youth Compared With Adults: Lessons From the RISE Study

  Diabetes Care · 2021-06-15 · 19 citations

  articleOpen access

  OBJECTIVE To determine whether β-cell hyperresponsiveness and insulin resistance in youth versus adults in the Restoring Insulin Secretion (RISE) Study are related to increased glucagon release. RESEARCH DESIGN AND METHODS In 66 youth and 350 adults with impaired glucose tolerance (IGT) or recently diagnosed type 2 diabetes (drug naive), we performed hyperglycemic clamps and oral glucose tolerance tests (OGTTs). From clamps we quantified insulin sensitivity (M/I), plasma fasting glucagon and C-p…

  PublisherOA PDFDOI

Recent grants

• Training Grant in Circadian and Sleep Research-Resubmission

  NIH · $9.1M · 1998–2030

• NIH Grant R01DK041814

  NIH · $2.0M · 2005

• NIH Grant U01DK094431

  NIH · $5.1M · 2020

Frequent coauthors

• Rachel Leproult

  Université Libre de Bruxelles

  184 shared

• Georges Copinschi

  Université Libre de Bruxelles

  134 shared

• Derk‐Jan Dijk

  University of Surrey

  87 shared

• Étienne Challet

  Institut des Neurosciences Cellulaires et Intégratives

  85 shared

• Karine Spiegel

  85 shared

• E. R. de Kloet

  Leiden University Medical Center

  83 shared

• Alexandros N. Vgontzas

  Pennsylvania State University

  82 shared

• Emanuela Arvat

  University of Turin

  81 shared

Labs

• Eve Van CauterPI

Education

• Ph.D., Medicine

  University of Chicago

  1989

• M.D., Medicine

  University of Chicago

  1983

• B.A., Biology

  University of Chicago

  1979

Similar researchers at University of Chicago

• Graeme Bellh-141
• Christopher Rhodesh-113
• Brian Won-Sik Kimh-105