About

Gregory S. Georgiade is a Professor of Surgery at Duke University. He is associated with the Department of Surgery and is based at 141 Baker House, Durham, NC 27710. His academic and clinical focus includes Plastic, Maxillofacial, and Oral Surgery, as well as General Surgery. He is involved in residency programs in General Surgery and Integrated Plastic and Reconstructive Surgery, and also participates in a Breast Surgical Oncology Fellowship. His work encompasses education, training, and research within the Duke Department of Surgery, contributing to the advancement of surgical practices and education at Duke University.

Research topics

• Medicine
• Surgery
• General surgery
• Internal medicine
• Dentistry

Selected publications

• Breast-Related Quality of Life in Young Reduction Mammaplasty Patients: A Long-Term Follow-Up Using the BREAST-Q

  Plastic & Reconstructive Surgery · 2019-11-01 · 40 citations

  articleSenior author

  BACKGROUND: Reduction mammaplasty is the most effective means of improving symptoms of macromastia. Although studies have shown lasting benefits in adult patients, there is a paucity of data that explore this topic in young patients. In this study, the long-term satisfaction and well-being of young reduction mammaplasty patients was assessed. METHODS: A retrospective review was performed for all female patients younger than 25 years who underwent reduction mammaplasty performed by a single surgeon from 1980 to 2003. Demographic characteristics, comorbidities, surgical details, and length of follow-up were recorded. Participants completed the postoperative version of the BREAST-Q Reduction module. Responses were scored on a scale of 0 to 100. Scores were summarized with descriptive statistics and compared to normative values. RESULTS: Thirty-seven of 52 eligible participants completed the survey (response rate, 71.2 percent). Median age at surgery was 21 years (range, 12.4 to 24.6 years), and median follow-up was 21.4 years (range, 11.4 to 32.4 years). Overall, participants demonstrated high satisfaction and well-being. Mean Q-Scores for Satisfaction with Breasts and Sexual Well-being were significantly higher than normative values (p = 0.0012 and p < 0.0001, respectively), and were as follows: Satisfaction with Breasts, 66.6 ± 16.5 (normative, 57 ± 16); Psychosocial Well-being, 75.9 ± 21.3 (normative, 68 ± 1 9); Sexual Well-being, 72 ± 18.2 (normative, 55 ± 19); and Physical Well-being, 81.1 ± 13.6 (normative, 76 ± 11). CONCLUSIONS: Young reduction mammaplasty patients experience excellent breast-related quality of life decades after surgery. Compared with normative values, young reduction mammaplasty patients reported higher satisfaction with breasts and sexual well-being. Surgeons and third-party payers should be aware of these data and advocate for young patients to gain access to care.

  PublisherDOI

• Architectural Distortion Caused by an Accessory Axillary Muscle

  Journal of Breast Imaging · 2019-08-02

  articleSenior author
  PublisherDOI

• Abstract 119: Long-Term Satisfaction in Young Reduction Mammaplasty Patients: a 30 Year Follow-Up Using the Breast-Q

  Plastic & Reconstructive Surgery Global Open · 2017-04-01

  articleOpen accessSenior author

  PURPOSE: Reduction mammaplasty is the most effective means of improving symptomatic macromastia. Although studies have shown lasting improvement in middle-aged patients, there is a paucity of data regarding young patients. With the growing obesity epidemic, more young patients are requesting reduction mammaplasty, signifying a need for long-term outcomes data. We hypothesize that young reduction mammaplasty patients experience excellent long-term quality of life and overall satisfaction. METHODS: Female patients less than 25 years of age who underwent reduction mammaplasty by a single surgeon from 1980–2004 were identified (n = 134). Contact information was obtained for 52 patients, for which 47 consented to participate. These patients were then mailed BREAST-Q Post-Operative Reduction Module surveys. Completed surveys were scored on a scale of 0–100 using the Qscore software. Demographic characteristics, comorbidities, surgical details, and length of follow-up were also reviewed. RESULTS: Thirty-six surveys were returned (response rate: 76.6%). The average age at surgery was 20.2 years (range: 12.4–24.6 years), with a mean follow-up of 21.2 years (range: 11.4–32.4 years). The mean BMI at surgery was 29.2. The inferior pedicle reduction technique was used in all cases. For satisfaction domains, mean scores were as follows: breasts, 66.9; outcome, 78.1. Regarding quality of life domains, mean scores were as follows: psychosocial, 76.1; sexual, 72.8; physical, 81.0. BMI <25 at the time of surgery was not a statistically significant predictor of long-term satisfaction or well-being. CONCLUSION: This study provides the longest follow-up of young reduction mammaplasty patients, and it is the only study to use the validated BREAST-Q in this population. Compared to normative values, young reduction mammaplasty patients more than ten years out from the procedure demonstrated higher scores across all domains. Surgeons should be aware of these data and advocate for their young patients to gain access to care.

  PublisherDOI

• Pathologic Response and Acute Toxicity: Planned Interim Analysis of the Phase 2 NeoRT Trial Evaluating Preoperative Single Fraction Partial Breast Radiation Therapy in Early Stage Breast Cancer

  International Journal of Radiation Oncology*Biology*Physics · 2017-09-23

  article
  PublisherDOI

• Preoperative Partial Breast Radiation Therapy: Short-term Imaging Outcomes With Two Unique Treatment Regimens

  International Journal of Radiation Oncology*Biology*Physics · 2015-10-17

  articleOpen access
  PublisherOA PDFDOI

• Impact of delayed lymphoscintigraphy for sentinel lymphnode biopsy for breast cancer

  Journal of Surgical Oncology · 2015-05-07 · 14 citations

  article

  BACKGROUND: Despite universal adoption of sentinel lymph node biopsy (SLNB) for breast cancer, there remains no standardized protocol for preoperative lymphoscintographic assessment of sentinel nodes. Both immediate and delayed lymphoscintigraphy are currently utilized, although it is unclear how delayed imaging impacts SLN identification. METHODS: Among patients diagnosed with breast cancer who underwent SLNB at Duke from 2011 to 2012, two protocols for preoperative lymphoscintigraphy were used: protocol A included both immediate and delayed lymphoscintigraphy (n = 152), while protocol B involved immediate lymphoscintigraphy only (n = 103). RESULTS: The overall intraoperative SLN identification rate was 98.4% and did not differ between groups. A lower number of SLN were visualized on the immediate scan using protocol A compared to protocol B (P < 0.001). Although a greater total number of nodes was excised using protocol A, this result was not statistically significant (P = 0.08). Moreover, there was no significant difference in the number of negative SLN between groups (P = 0.51). CONCLUSIONS: We found no significant impact on identification rate or number of SLN excised with the use of delayed versus immediate imaging. These findings support abandoning delayed lymphoscintographic imaging, except in those cases where aberrant drainage is suspected.

  PublisherDOI

• Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers

  International Journal of Radiation Oncology*Biology*Physics · 2015-03-14 · 145 citations

  article
  PublisherDOI

• Preoperative External Beam APBI: Report of Acute Toxicities From 2 Prospective Clinical Trials Using Two Different Fractionation Schemes

  International Journal of Radiation Oncology*Biology*Physics · 2015-10-17

  articleOpen access
  PublisherOA PDFDOI

• Preoperative Partial Breast Radiation Therapy: One Year Outcomes and Radiation-Induced Changes in Gene Expression

  International Journal of Radiation Oncology*Biology*Physics · 2014-09-01

  articleOpen access
  PublisherOA PDFDOI

• Effect of Obesity on Procedure Selection and Satisfaction with Breast Cancer Procedures

  Plastic & Reconstructive Surgery · 2014-09-26 · 2 citations

  articleOpen access

  BACKGROUND: The incidence and prevalence of breast cancer and obesity continue to rise. Previous studies have shown that body mass index (BMI) predicts patient satisfaction with breast reconstruction (BR). Does BMI influence procedure type and satisfaction with all breast cancer procedures? METHODS: The Army of Women (AOW) comprises over 360,000 women who voluntarily participate in breast cancer research. Women enrolled with history of breast cancer surgery were recruited to take surveys including; BREAST-Q©, PTSD checklist, Impact of Cancer scale, and demographic survey. Patient data was classified by BMI. Regression analysis was used to evaluate effect of procedure type on breast satisfaction for each BMI category. RESULTS: 7,568 women completed all surveys. Distribution of procedure type by BMI differed significantly. As BMI increased rate of mastectomy increased (p<0.0001). Those with higher BMI, had lower rates of BR and higher rates of breast conservation surgery (BCS) (p<0.0001). Overweight, obese, and morbidly obese women reported similar satisfaction with BR and BCS (Table 1). Regression analysis revealed that all women experienced higher satisfaction with BR using abdominal flaps, even when compared to BCS (p<0.0001, Figure 1). Women with mastectomy experienced the lowest satisfaction when compared to BCS (p<0.0001).Table 1: Mean Breast Satisfaction Score (0-100) Mean (sd): P-values range from 0.0095 to < 0.000.Figure 1: Figure 1.CONCLUSIONS: Women with larger BMI experience significantly higher rates of mastectomy alone without reconstruction despite having higher satisfaction with reconstruction and similar satisfaction with breast conservation surgery. This supports the notion that all patients being considered for mastectomy should be referred to a plastic surgeon for evaluation and plastic surgeons should highly consider use of abdominal flap reconstruction in this population, despite increased risk of complications.

  PublisherOA PDFDOI

Frequent coauthors

• Ronald Riefkohl

  76 shared

• Nicholas G. Georgiade

  Durham Technical Community College

  58 shared

• William J. Barwick

  34 shared

• Donald Serafín

  32 shared

• Anna R. Carlson

  Helen DeVos Children's Hospital

  21 shared

• Ronnie L. Shammas

  Duke University

  21 shared

• Kenneth S. McCarty

  21 shared

• N Georgiade

  20 shared