David Goldstein

About

David Goldstein holds a joint position in the Department of Linguistics and the Program in Indo-European Studies at UCLA, with a courtesy appointment in the Department of Classics. His research focuses on the intersection of language change and linguistic theory, specifically examining syntactic, morphosyntactic, and semantic change among the Indo-European languages. He is a member of the 2021 cohort of Guggenheim Fellows. Goldstein's educational background includes a Ph.D. from the University of California, Berkeley, earned in 2010, an M.A. from Berkeley in 2004, an M.Phil. from the University of Oxford's Corpus Christi College in 2002, and a B.A. from Amherst College in 2000.

Research topics

• Artificial Intelligence
• Computer Science
• Machine Learning
• Natural Language Processing
• Mathematics
• Sociology
• Mathematical optimization
• Statistics
• History
• Astrobiology

Selected publications

• Indo-European phylogenetics with R

  Indo-European Linguistics · 2020 · 10 citations

  1st authorCorresponding

  Abstract The last twenty or so years have witnessed a dramatic increase in the use of computational methods for inferring linguistic phylogenies. Although the results of this research have been controversial, the methods themselves are an undeniable boon for historical and Indo-European linguistics, if for no other reason than that they allow the field to pursue questions that were previously intractable. After a review of the advantages and disadvantages of computational phylogenetic methods, I…

  DOI

• Supplemental Figure S1 from The NCI-60 Methylome and Its Integration into CellMiner

  2023-03-31

  preprintOpen access

  <p>Methylation gene probe selection and correlation to expression level.</p>

  PublisherDOI

• Supplemental Table S3 from The NCI-60 Methylome and Its Integration into CellMiner

  2023-03-31

  preprintOpen access

  <p>Linear regression analysis of 15,798 genes with with transcript expression, DNA methylation, and DNA copy number data available.</p>

  PublisherDOI

• Supplemental Figure S1 from The NCI-60 Methylome and Its Integration into CellMiner

  2023-03-31

  preprintOpen access

  <p>Methylation gene probe selection and correlation to expression level.</p>

  PublisherDOI

• Data from The NCI-60 Methylome and Its Integration into CellMiner

  2023-03-31

  preprintOpen access

  <div>Abstract<p>A unique resource for systems pharmacology and genomic studies is the NCI-60 cancer cell line panel, which provides data for the largest publicly available library of compounds with cytotoxic activity (∼21,000 compounds), including 108 FDA-approved and 70 clinical trial drugs as well as genomic data, including whole-exome sequencing, gene and miRNA transcripts, DNA copy number, and protein levels. Here, we provide the first readily usable genome-wide DNA methylation d…

  PublisherDOI

Recent grants

• CCR Sequencing Facility

  NIH · $68.2M

• NIH Grant R29CA063044

  NIH · $432k · 1999

• Roles and regulation of aqua/glyceroporins in a freeze tolerant amphibian

  NSF · $562k · 2011–2016

Frequent coauthors

• J-F. Arguin

  86 shared

• E. J. Jeon

  Institute for Basic Science

  83 shared

• A. Warburton

  McGill University

  80 shared

• G. Latino

  Istituto Nazionale di Fisica Nucleare, Sezione di Firenze

  79 shared

• A. Cerri

  77 shared

• D. MacQueen

  University of Alberta

  73 shared

• K. K. Joo

  69 shared

• D. J. Kong

  Kumamoto University

  64 shared

Education

• Ph.D., Physics and Astronomy

  University of California Los Angeles

  2004

Awards & honors

• 2021 cohort of Guggenheim Fellows

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