About

Cibele Nasri-Heir is an Associate Professor at Rutgers School of Dental Medicine, working within the Department of Diagnostic Sciences. Her primary research focuses on chronic orofacial pain, with a particular interest in burning mouth syndrome. Her work involves investigating sensory function and pain modulation in various orofacial neuropathic pain conditions, including post-traumatic trigeminal neuropathy and chronic masticatory myalgia. She explores the role of pain modulation systems, the effects of exercise-induced hypoalgesia, and sensory and genetic factors related to atypical odontalgia and postoperative pain following dental surgeries. Dr. Nasri-Heir has contributed to the development of research diagnostic criteria for burning mouth syndrome and has been involved in evaluating therapeutic interventions for orofacial pain conditions.

Selected publications

• Comparison of three methods for treatment of temporomandibular disorders

  http://isrctn.com/ · 2024-11-13

  dataset
  PublisherDOI

• Temporomandibular Joint Disorders and the Eating Experience

  Dental Clinics of North America · 2023-02-01 · 7 citations

  article1st author
  PublisherDOI

• Use of compounded topical medications for treatment of orofacial pain: a narrative review

  Journal of Oral and Maxillofacial Anesthesia · 2022-08-12 · 5 citations

  reviewOpen accessSenior author

  Background and Objective: Orofacial pain is a frequent form of pain perceived in the face and/or oral cavity. It may be caused by diseases or disorders of regional structures, dysfunction of the nervous system, or through referral from distant sources. The objective of the narrative review is to describe the classifications of orofacial pain, potential targets for pharmacotherapeutic treatment and discusses the novel topical administration of already approved medications for management. Actual cases will be presented illustrating administration and efficacy. Methods: Electronic databases (PubMed, Embase, Ovid Medline, Google scholar, Scopus, Cochrane library) were searched using keywords “Topical medications” and “Orofacial Pain” from 1st January 1974 to 30th November 2021. A total of 280 articles were identified and relevant 105 articles were included in the review. Key Content and Findings: The multifactorial etiology of orofacial pain requires an accurate diagnosis in order to appropriately treat. Treatment of orofacial pain typically includes pharmacotherapy, which can only be effective if the source of pain is clearly identified. In most cases of orofacial pain, primary treatment includes pharmacotherapy. The pharmacotherapeutic agents required to treat the majority of orofacial pain disorders are associated with significant side effects, interactions, and complications. Administration of medications topically avoids many, if not all side effects. Topical administration of approved medications for neuropathic and musculoskeletal pain offers a unique delivery system that can improve the quality of life while avoiding systemic side effects. Conclusions: Topical medications offer safe and effective strategy for management of neuropathic and musculoskeletal orofacial pain while avoiding significant side effects. Topical administration is especially useful for the medically complex, compromised, or elderly patients with comorbid medical conditions or those using other medications which may contraindicate the systemic administration of otherwise appropriate pharmacotherapeutics.

  PublisherDOI

• Reply to Currie et al.

  Pain · 2022-04-18

  articleOpen access

  We would like to thank Currie et al.3 for initiating a discussion on our recent publication to rename and improve the International Classification of Diseases-11 disease criteria for burning mouth syndrome.4 In this article, we presented the results of a consensus reached by an international group of experts using the Delphi methodology.2

  PublisherOA PDFDOI

• Renaming burning mouth syndrome: implications and use for the Research Diagnostic Criteria for Burning Mouth Syndrome

  Pain · 2022-04-18 · 6 citations

  letterOpen access

  TEST 02 - Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicine, social sciences and arts and humanities fields.

  PublisherOA PDFDOI

• Author response for "<scp>WWOM VII</scp> : Effectiveness of Topical Interventions in the Management of Burning Mouth Syndrome: A Systematic Review"

  2022-05-13

  peer-review
  PublisherDOI

• <scp>WWOM VII</scp> : Effectiveness of topical interventions in the management of burning mouth syndrome: A systematic review

  Oral Diseases · 2022-07-04 · 14 citations

  review

  OBJECTIVES: To assess the effectiveness of topical interventions in the management of burning mouth syndrome (BMS), based on the core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT). METHODS: A systematic literature review of RCTs on topical interventions for the management of BMS, published in PubMed, Web of Science, PsycInfo, Cochrane Database/Central, and Google Scholar through May 2021 was performed. RESULTS: Eight RCTs (n = 358 study participants) were included in this study. Due to underreporting of IMMPACT domains, publication bias, high degree of heterogeneity between studies, meta-analysis was not undertaken. Based on changes in visual analogue pain scores (ΔVAS), the most reported outcome, the effectiveness of the topical interventions was demonstrated; however, it is low level of evidence. CONCLUSIONS: High levels of variability (interventions, outcomes, outcome measurement tools, and intervention effects evaluated), heterogeneity, publication bias, and underreporting of IMMPACT domains were observed across the RCTs. This systematic review highlights the need for application of standardized outcome measures to future RCTs. At the present time, there is lack of moderate-strong evidence on short- and long-term outcomes to support or refute the use of any particular topical intervention in managing BMS. Future RCTs with standardized outcome measures are needed.

  PublisherDOI

• Sensory Changes Related to Dental Implant Placement: A Scoping Review

  Journal of Oral & Facial Pain and Headache · 2022-05-01 · 9 citations

  reviewOpen access

  AIMS: To perform a scoping review of the literature to elucidate the occurrence of nerve damage related to dental implant placement and the factors causing the sensory changes. METHODS: An extensive electronic search was conducted using the Cochrane Library, Medline via Ovid, PubMed, Wiley Online, Science Direct, CINAHL, and the Google Scholar databases from the year 1950 to 2020. RESULTS: The search resulted in 1,067 articles, out of which 76 were selected for this review. The articles were categorized as literature review articles, retrospective studies, prospective studies, and case series/case reports. Altogether, 2,526 subjects were assessed retrospectively, with 5.27% transient and 1.39% persistent sensory changes, and a cohort of 2,750 subjects were followed prospectively, with 6.22% transient and 1.31% persistent sensory changes. A total of 336 subjects were enrolled in various case reports and case series, with 5.95% transient sensory changes and 84.52% persistent neurosensory changes. The articles included were not of high quality and have variations in their study designs and reporting procedures, with limited sensory change data to include in this study. CONCLUSION: After surgical placement of dental implants in 5,612 patients, the incidence of transient sensory changes was 5.63%, and the incidence of persistent sensory changes was 6.33%. Factors affecting the incidence were: mandibular location of the implant, with the inferior alveolar nerve as the most commonly affected nerve. The common symptoms reported were paresthesia and dysesthesia. Age and gender were among other factors, for which data were not available in all the articles.

  PublisherOA PDFDOI

• Author response for "WWOM VII: Effectiveness of systemic pharmacotherapeutic interventions in the management of BMS: A systematic review and meta‐analysis"

  2021-02-08

  review
  PublisherDOI

• Correction to: IMMPACT-recommended outcome measures and tools of assessment in burning mouth syndrome RCTs: an international Delphi survey protocol

  Trials · 2021-03-22

  articleOpen access

  An amendment to this paper has been published and can be accessed via the original article.

  PublisherOA PDFDOI