Christopher Schmid

About

Christopher H. Schmid, PhD, is a Professor of Biostatistics and a former Chair of the Department of Biostatistics at Brown University. He is a founding member of the Center for Evidence Synthesis in Health at the Brown School of Public Health. His research focuses on methods and applications for meta-analysis, particularly Bayesian methods and software, as well as predictive models derived from combining data from different sources. He has a special interest in clinical trials, including N-of-1 trials and single-person multiple crossover studies, and has published extensively on meta-regression, multivariate methods, network meta-analysis, and the integration of N-of-1 studies. Dr. Schmid has contributed to the development of national standards for systematic reviews through the Institute of Medicine and has collaborated with medical and public health scientists on numerous applications. He holds a PhD in Statistics from Harvard University and a BA in Mathematics from Haverford College. Prior to his current position, he was on the faculty at Tufts University School of Medicine, where he served as Director of the Biostatistics Research Center and as Associate Director of the Clinical and Translational Science program.

Research topics

• Medicine
• Computer Science
• Applied psychology
• Medical physics
• Traditional medicine
• Genetics
• Environmental health
• Surgery
• Botany
• Biology

Selected publications

• Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses

  Canadian Medical Association Journal · 2020 · 693 citations

  BACKGROUND: Most randomized controlled trials (RCTs) and meta-analyses of RCTs examine effect modification (also called a subgroup effect or interaction), in which the effect of an intervention varies by another variable (e.g., age or disease severity). Assessing the credibility of an apparent effect modification presents challenges; therefore, we developed the Instrument for assessing the Credibility of Effect Modification Analyses (ICEMAN). METHODS: To develop ICEMAN, we established a detailed…

  DOI

• Effect of Pod e-Cigarettes vs Cigarettes on Carcinogen Exposure Among African American and Latinx Smokers

  JAMA Network Open · 2020 · 106 citations

  Importance: Fourth-generation nicotine salt pod system (NSPS) electronic cigarettes (e-cigarettes) are the leading class of e-cigarettes. They contain high nicotine concentrations, which may facilitate switching among smokers, but could also lead to increased exposure to nicotine and biomarkers of potential harm. African American and Latinx smokers experience significant tobacco-related health disparities. The potential of NSPS e-cigarettes to reduce smoking-related harm among these groups is un…

  DOI

• Pay-for-Performance Incentives for Home Dialysis Use and Kidney Transplant

  JAMA Health Forum · 2024-06-30 · 16 citations

  articleOpen access

  Importance: The Centers for Medicare & Medicaid Services' mandatory End-Stage Renal Disease Treatment Choices (ETC) model, launched on January 1, 2021, randomly assigned approximately 30% of US dialysis facilities and managing clinicians to financial incentives to increase the use of home dialysis and kidney transplant. Objective: To assess the ETC's association with use of home dialysis and kidney transplant during the model's first 2 years and examine changes in these outcomes by race, ethnici…

  PublisherOA PDFDOI

• A comparison of the NIRUDAK models and WHO algorithm for dehydration assessment in older children and adults with acute diarrhoea: a prospective, observational study

  The Lancet Global Health · 2023-09-27 · 13 citations

  articleOpen access

  BackgroundDespite the importance of accurate and rapid assessment of hydration status in patients with acute diarrhoea, no validated tools exist to help clinicians assess dehydration severity in older children and adults. The aim of this study is to validate a clinical decision support tool (CDST) and a simplified score for dehydration severity in older children and adults with acute diarrhoea (both developed during the NIRUDAK study) and compare their accuracy and reliability with current WHO g…

  PublisherOA PDFDOI

• HIV Pre-exposure Prophylaxis Use Among Men Experiencing Incarceration in the United States: A Prospective Cohort Study

  JAIDS Journal of Acquired Immune Deficiency Syndromes · 2024-04-22 · 3 citations

  articleOpen access

  BACKGROUND: Pre-exposure prophylaxis (PrEP) is an effective approach to preventing HIV acquisition and recommended for populations over-represented in carceral systems, given the overlap with populations disproportionately impacted by HIV. However, few studies have focused on PrEP initiation outcomes in a carceral setting to maximize public health impact. SETTING: This study was conducted in a unified jail/prison system within the state of Rhode Island located in the United States. METHODS: A pr…

  PublisherOA PDFDOI

Recent grants

• NIH Grant R01HS008532

  NIH · $422k · 1998

• NIH Grant R33RR017109

  NIH · $1.2M · 2006

• NIH Grant R01HS010064

  NIH · $698k · 2002

Frequent coauthors

• Issa J Dahabreh

  315 shared

• John P. A. Ioannidis

  Stanford University

  302 shared

• Xin Sun

  West China Hospital of Sichuan University

  256 shared

• Ravi Varadhan

  256 shared

• Geert J. M. G. van der Heijden

  University of Amsterdam

  256 shared

• Joel Gagnier

  Western University

  256 shared

• Stefan Schandelmaier

  University of Basel

  256 shared

• Rodney A. Hayward

  VA Center for Clinical Management Research

  256 shared

Education

• Ph.D.

  Harvard University

  1991

• B.A.

  Haverford College

  1983

Awards & honors

• Fellow of the American Statistical Association (ASA)
• Elected member of the Society for Research Synthesis Methodo…
• Founding Editor of the journal Research Synthesis Methods
• Chair of the Section on Health Policy Statistics at ASA

Similar researchers at Brown University

• Constantine Gatsonish-91
• Thomas Trikalinosh-89
• George Papandonatosh-70