Christopher Rhodes
University of Chicago · Endocrinology, Diabetes and Metabolism
Active 1915–2026
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About
Christopher Rhodes is an Emeritus/Emerita Professor at the University of Chicago in the Department of Medicine-Endocrinology. His research activities and funding have focused on pancreatic islet function, metabolic control of proinsulin biosynthesis, insulin exocytosis, and signal transduction in pancreatic beta-cells. He has led multiple NIH-funded projects, including studies on central control of pancreatic islet function and interdisciplinary molecular metabolism training. His work has contributed to understanding the metabolic regulation of insulin and proinsulin, as well as the cellular mechanisms underlying pancreatic beta-cell function. Rhodes has also been involved in research related to pulmonary arterial hypertension, pulmonary vascular disease, and the role of ferroptosis and inflammation in pulmonary hypertension. His publications include studies on pulmonary arterial hypertension, lung metabolism, and the genetic determinants of right ventricular structure and function, reflecting a broad focus on metabolic and vascular diseases.
Research topics
- Biology
- Medicine
- Genetics
- Internal medicine
- Cardiology
- Bioinformatics
- Pathology
- Computational biology
Selected publications
Whole-genome sequencing of patients with rare diseases in a national health system
Nature · 2020 · 575 citations
Whole-genome sequencing of a sporadic primary immunodeficiency cohort
Nature · 2020 · 238 citations
From New World Order to War on Terror
2026-01-02
book-chapter1st authorCorrespondingEnrichment of Cysteine S-palmitoylated Peptides Using Sodium Deoxycholate Acid Precipitation
Molecular & Cellular Proteomics · 2025-10-17
articleOpen accessS-palmitoylation is a poorly understood post-translational modification that is gaining more attention as an essential regulator of cellular processes. The reversible nature of S-palmitoylation may allow for fine-tuned control of cellular events and adaptation to stimuli. The detection of S-palmitoylated proteins and peptides includes the Acyl-Biotin Exchange (ABE) method, Acyl resin-assisted Capture (Acyl-RAC), metabolic labelling, and derivatives thereof. We present a novel method of enrichmen…
Recent grants
NIH · $380k · 2010
NIH · $3.0M · 2007
NIH · $1.9M · 2019
Frequent coauthors
- 333 shared
Martin R. Wilkins
Imperial College London
- 266 shared
John Wharton
Imperial College London
- 220 shared
Nicholas W. Morrell
- 139 shared
Luke Howard
Imperial College Healthcare NHS Trust
- 134 shared
Timothy J. Aitman
- 123 shared
Almaz Aldashev
- 122 shared
Baktybek Kojonazarov
University of Giessen
- 121 shared
Michael A. Marletta
University of California, Berkeley
Labs
Christopher Rhodes LabPI
Education
- 2011
PhD, Pharmacology & Therapeutics, Medicine
Imperial College London
- 2007
BA, Natural Sciences: Pharmacology
University of Cambridge
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