Christopher Mariani

About

Sarah Ho is the CVM Director of Student Engagement at the College of Veterinary Medicine at NC State University. Her role involves fostering student development and engagement within the college community. The page does not provide specific details about her research focus, background, or key contributions beyond her position and responsibilities related to student engagement.

Research topics

• Medicine
• Cancer research
• Orthodontics
• Surgery
• Anatomy
• Pathology
• Biology
• Internal medicine
• Radiology
• Biomedical engineering

Selected publications

• Accuracy of three‐dimensionally printed animal‐specific drill guides for implant placement in canine thoracic vertebrae: A cadaveric study

  Veterinary Surgery · 2020 · 32 citations

  1st authorCorresponding

  OBJECTIVE: To assess the accuracy of three-dimensionally (3-D) printed drill guides in constraining the trajectory of drill tracts for implants in canine thoracic vertebrae. STUDY DESIGN: Experimental ex vivo study. SAMPLE POPULATION: Five canine thoracic vertebral column specimens. METHODS: Guides to constrain drill trajectories were designed on the basis of computed tomographic (CT) imaging of six thoracic vertebrae (T8-T13) and were 3-D printed. The guides were used to create drill tracts in…

  DOI

• Accuracy and safety of three‐dimensionally printed animal‐specific drill guides for thoracolumbar vertebral column instrumentation in dogs: Bilateral and unilateral designs

  Veterinary Surgery · 2020 · 27 citations

  Senior authorCorresponding

  OBJECTIVE: To evaluate the safety and accuracy of a unilateral three-dimensionally printed animal-specific drill guide (3DASDG) design for unilateral stabilization in the thoracolumbar vertebral column of dogs compared to a bilateral design. STUDY DESIGN: Cadaveric study. SAMPLE POPULATION: Fifty-two corridors in one canine cadaver. METHODS: Two 3DASDG designs with 2 drilling tubes each were created from T8 to L7 vertebrae. Fifty-two corridors were drilled on the right and the left sides by usin…

  DOI

• Immunohistochemical evaluation of immune cell infiltration in canine gliomas

  Veterinary Pathology · 2021 · 25 citations

  Senior authorCorresponding

  = .005). These data warrant further exploration into the roles of macrophage repolarization or Treg interference therapy in canine glioma.

  PublisherOA PDFDOI

• Association between anesthesia duration and outcome in dogs with surgically treated acute severe spinal cord injury caused by thoracolumbar intervertebral disk herniation

  Journal of Veterinary Internal Medicine · 2020 · 24 citations

  BACKGROUND: Retrospective research recently identified a possible relationship between duration of surgery and outcome in severely affected dogs treated surgically for acute thoracolumbar intervertebral disk herniation (TL-IVDH). HYPOTHESIS: That increased duration of surgery is associated with poorer outcome in dogs with absent pain perception treated surgically for TL-IVDH. ANIMALS: Two hundred ninety-seven paraplegic dogs with absent pain perception surgically treated for acute TL-IVDH. METHO…

  PublisherOA PDFDOI

• Personalized‐induced neural stem cell therapy: Generation, transplant, and safety in a large animal model

  Bioengineering & Translational Medicine · 2020 · 16 citations

  In this study, we take an important step toward clinical translation by generating the first canine-induced neural stem cells (iNSCs). We explore key aspects of scale-up, persistence, and safety of personalized iNSC therapy in autologous canine surgery models. iNSCs are a promising new approach to treat aggressive cancers of the brain, including the deadly glioblastoma. Created by direct transdifferentiation of fibroblasts, iNSCs are known to migrate through the brain, track down invasive cancer…

  DOI

Frequent coauthors

• Natasha J. Olby

  North Central State College

  43 shared

• Peter J. Early

  North Carolina State University

  39 shared

• Karen R. Muñana

  North Carolina State University

  37 shared

• Cheryl L. Chrisman

  University of Florida

  16 shared

• Aude Castel

  Université de Montréal

  15 shared

• Julien Guevar

  12 shared

• Simon R. Platt

  11 shared

• Wolfgang J. Streit

  University of Florida

  10 shared

Education

• Ph.D., Comparative Medicine

  North Carolina State University

  2004

• M.S., Comparative Medicine

  North Carolina State University

  2001

• B.S., Animal Science

  University of Florida

  1998

Awards & honors

• Diplomate, American College of Veterinary Internal Medicine…

Similar researchers at North Carolina State University

• Edward Breitschwerdth-100
• B. Duncan X. Lascellesh-67
• Craig Harmsh-54