About

Nitin Pandey, PhD, is an Assistant Professor of Research in Physiology and Neuroscience at the Keck School of Medicine of USC. His research focuses on the conformational interactions and aggregation pathways of proteins such as TDP43 and huntingtin exon-1, with particular emphasis on understanding the mechanisms underlying protein fibril formation, membrane interactions, and aggregation-related toxicity. His work involves exploring the structural and biochemical properties of these proteins, contributing to the broader understanding of neurodegenerative diseases and protein misfolding disorders.

Research topics

• Internal medicine
• Medicine
• Pediatrics
• Stereochemistry
• Gerontology
• Demography
• Biochemistry
• Surgery
• Chemistry

Selected publications

• Electrophototherapeutic Resources Associated or Not With Exercise and Dosimetry Used in Subacromial Impingement Syndrome: A Scoping Review

  Physical Therapy Korea · 2025-08-20

  articleOpen access

  Kauanny Lopes Pereira, PT, Renata Anddresa Stacheslki, PT, Alberito Rodrigo de Carvalho, PT, PhD, Gladson Ricardo Flor Bertolini, PT, PhD, Márcia Rosângela Buzanello, PT, PhD. Phys. Ther. Korea 2025;32:91-110. https://doi.org/10.12674/ptk.2025.32.2.91

  PublisherOA PDFDOI

• Comparison of Sonographic Quantitative Assessment of Splenomegaly in Thalassemia Patients Receiving Whole Blood and Packed Red Cell Transfusions

  Advanced ultrasound in diagnosis and therapy · 2023-01-01

  articleOpen access

  Objective: An observational cross-sectional study to assess sonographic splenomegaly quantitatively in thalassemia patients grouped with respect to transfusion given whole blood vs packed red cells. Methods: A study was conducted among 330 patients equally divided into two groups, undergoing an abdominal ultrasound examination with a transducer frequency ranging from 3-5 MHz during the period December 2021 to August 2022. An independent t-test was applied to compare the splenic volume in thalassemia patients given whole blood transfusions versus packed red cells transfusions, and Cohen's d was used to indicate the standardized difference between two ultrasound splenic volume means. Results: The mean splenic volume of the patients who received whole blood cells was 320.62 ± 219.05 cm3, which is greater than the patients who received packed red cells, whose mean was 60.72 ± 58.72 cm3, The splenomegaly was quantitatively assessed in six age groups ranging from 1 to 3 years, 4 to 6 years, 7 to 9 years, 10 to 12 years, 13 to 15 years, and 16-18 years and mean splenic volume in each age group was compared to those receiving whole blood or packed red cells transfusion. there is a statistically significant difference between both transfusion receiving groups, having a larger Cohen’s d size effect of 1.62. Conclusion: Ultrasound is a reliable imaging modality for assessing splenic volume and linear parameters of the spleen with greater splenomegaly in thalassemia patients with whole blood transfusions than those with packed red cells when quantitatively assessed according to relevant age groups. Thalassemia patients should be transfused packed red cells to delay splenomegaly, that should be assessed sonographically.

  PublisherDOI

• SYNTHESIS, CHARACTERIZATION, IN SILICO OPTIMIZATION, AND CONFORMATIONAL STUDIES OF METHYL 4-O-PIVALOYL-α-L-RHAMNOPYRANOSIDES

  Malaysian Journal of Science · 2022 · 5 citations

  • Chemistry
  • Stereochemistry
  • Biochemistry

  Considering promising biological activities of natural and synthetic rhamnopyranoside esters, we have synthesized several methyl 4-O-pivaloyl-α-L-rhamnopyranosides via selective 2,3-O-acetonide protection of methyl α-L-rhamnopyranoside (4) followed by C-4 pivaloylation, and deprotection. The synthesized 4-O-pivaloate 7 and its 2,3-di-O-esters 8a-e are characterized by spectroscopy and are optimized by using density functional theory (DFT). The free energy and bond angles thus calculated are used to establish the probable conformation(s). The 2,3-O-acetonide protected rhamnopyranosides 5-6 are found to be slightly distorted from the regular 1C4 conformation, and exist between the chair and twist-boat (skew) conformation while other pivaloyl esters 7-8a-e exist in regular 1C4 chair conformation.

  PublisherOA PDFDOI

• A savings intervention to reduce men's engagement in HIV risk behaviors: study protocol for a randomized controlled trial

  Research Square · 2022-11-04

  preprintOpen access

  Abstract Background In much of eastern and southern Africa, the incidence of HIV and other sexually transmitted infections (STIs) remains high despite the scale-up of promising biomedical and behavioral interventions. Studies have documented the crucial role of transactional sex – the exchange of money, material support or goods in, sexual relationships – and heavy alcohol use in driving HIV/STI incidence and influencing men’s and women’s health outcomes. Existing policy responses to this challenge have largely focused on interventions to reduce women’s engagement in transactional sex such as vocational training and cash transfers for economic empowerment. However, the effectiveness of these interventions has been hindered by the relative lack of programs targeting men’s behavior. There is a vital need for interventions that can reduce men’s engagement in risky behaviors that increase HIV/STI risk. We describe here a protocol for an economic intervention to reduce men’s engagement in HIV risk behaviors in Kenya. Methods We will conduct a randomized controlled trial among income-earning men in Kenya who are aged 18–39 years and self-report alcohol use and engagement in transactional sex. The study will enroll 1,500 participants and randomize them to a control group or savings group. The savings group will receive access to a savings account that includes lottery-based incentives to save money regularly, opportunities to develop savings goals/strategies, and text message reminders about their saving goals. The control group will receive basic health education. Over a period of 24 months, we will collect qualitative and quantitative data from participants and a subset of their female partners. Participants will also be tested for HIV and other STIs at baseline, 12, and 24 months. Discussion The findings from this study have the potential to address a missing element of HIV/STI prevention efforts in Sub-Saharan Africa by promoting upstream and forward-looking behavior and reducing the risk of acquiring HIV/STIs in a high HIV/STI burden setting. If this study is effective, it is an innovative approach that could be scaled up and could have great potential for scientific and public health impact in Kenya. Trial registration : Registered on ClinicalTrials.gov on May 23, 2022. Link: https://clinicaltrials.gov/ct2/show/NCT05385484. Registration number: NCT05385484

  PublisherOA PDFDOI

• Comparison of Community Rehabilitation Services for the Elderly in South Korea and Japan: Focusing on the Long-Term Care Insurance System

  Physical Therapy Korea · 2022-05-19 · 3 citations

  articleOpen accessSenior author

  Background: As South Korea enters an aged society, the government has emphasized the need for a soft landing of the older adults into the community after the acute and recovery periods under a national policy of "community care." However, the institutionalization of community rehabilitation services to implement this is insufficient. Japan had already entered an aged society when the Long-Term Care Insurance System was introduced in 2000. Thus, the case of Japan's institutionalization of the system is expected to have implications for us in supplementing a suitable system for the aged society.

  PublisherOA PDFDOI

• The Effect of Non-elastic and Elastic Tapes on the Pain, Craniovertebral Angle, and Balance of Patients with a Forward Head Posture

  Journal of the Korean Society of Physical Medicine · 2022-11-30

  articleOpen accessSenior author

  This study was conducted to investigate the effects of non-elastic and elastic tapes on pain, craniovertebral angle, and balance in forward head posture (FHP) patients.

  PublisherOA PDFDOI

• WHAT’S ROLE OF LATE IODINE ENHANCEMENT CARDIAC COMPUTED TOMOGRAPHY IN THE CARDIOPATHIC PATIENT? -

  Journal of Cardiovascular Disease Research · 2021-01-01

  article

  In the clinical practice the cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) represents the gold standard for myocardial characterization: especially in the assessment of coronary artery disease (CAD), establishing a diagnosis of acute or chronic myocardial infarction (MI) and above all allowing a differential diagnosis with non-ischemic causes of myocardial damage (such as myocarditis, cardiomyopathies, etc.) [1]. In patients with severe contraindications to CMR, or with hemodynamic instability, the use of cardiac computed tomography angiography (CCTA) with the evaluation of iodine delayed-enhancement, or late iodine enhancement (CT-LIE), represents an alternative method to identify myocardial scars and allowing a tissue characterization, as some studies have already shown [2,3,4]. Here we reported a clinical case report in which CT-LIE has been demonstrated an effective alternative to perform myocardial characterization especially in complicated patients with hemodynamic instability.

  Publisher

• Sánchez Medina Mayra et José Ramón Fabelo Corzo (coords.), Coordenadas epistemológicas para una estética en construcción, México, Benemérita Universidad Autónoma de Puebla, 2020. ISBN (Instituto de Filosofía de la Habana): 978-607-525-676-4, ISBN (Benemérita Universidad Autónoma de Puebla): 978-959-7197-38-6, 384 pages.

  Artelogie · 2021-01-01

  articleOpen accessSenior author

  Le livre collectif Coordenadas epistemológicas para una estética en construcción [Coordonnés épistémologiques pour une esthétique en construction], sous la direction des chercheurs cubains Mayra Sánchez et José Ramón Fabelo, est à la recherche de nouveaux angles sur le concept de l’esthétique, afin de l’émanciper de sa territorialité épistémique dans le savoir européen continental qui se présente avec un caractère d’universel, ce qui fausse ce concept en laissant de côté d’autres savoirs et d...

  PublisherOA PDFDOI

• The University of North Carolina Heart-Lung Transplant Experience: Historical Perspective and Notes on Surveillance for Very Long-Term Survivors

  Journal of Patient Care · 2021 · 2 citations

  • Medicine
  • Surgery
  • Pediatrics

  Background: The University of North Carolina (UNC) pioneered heart-lung transplant (HLT) in the state of North Carolina in 1991. Specific guidelines for surveillance of very long-term survivors of HLT are non-existent. We report historical context for the UNC 30-year experience with HLT, complexity of subsequent medical care, and a standardized approach to follow-up. Methods: The medical and UNOS records for all patients who underwent HLT at UNC were reviewed. Demographics, perioperative details, and post-transplant medication regimens were abstracted. Early (30 day) and late (>30 days post HLT) morbidity was described, and Kaplan-Meier curves estimated long-term survival. Results: Overall, 15 patients (67% male, 73% adults) underwent HLT, and 80% had congenital heart disease. Five-, twenty-, and twenty-five-year survival was 40% (n=6), 27% (n=4), and 20% (n=3), respectively. All 15-year survivors (n=5) experienced late complications (infections-100%; chronic kidney disease-60%; malignancies-40%; and pulmonary allograft rejection-60%). None had cardiac graft rejection. Dedicated transplant cardiologists and pulmonologists directed long-term care, and survivors were followed every 6-12 months with non-invasive cardiopulmonary testing. Invasive testing with cardiac catheterization and/or bronchoscopy was performed every 2-3 years. Limitations: Limitations of the study include small sample size typical of a single-center study. However, this historicallysignificant series represents the entire HLT experience at UNC. Conclusion: UNC pioneered HLT in the state of North Carolina in 1991. HLT remains a rarely-performed, but viable option for end-staged cardiopulmonary failure as evidenced by favorable long-term survival. Late complications are common and warrant close surveillance and ongoing coordinated care by a specialized multi-disciplinary team.

  PublisherDOI

• Duodenal Duplication Cysts - A Case Report of the Oldest Man in Literature

  World Journal of Surgery and Surgical Research · 2021-02-02

  articleOpen access
  Publisher

Frequent coauthors

• David Grossberg Born

  Princeton University

  49 shared

• Mohr Siebeck

  Philipps University of Marburg

  49 shared

• Peter Schäfer

  49 shared

• Martha Himmelfarb Born

  Fordham University

  49 shared

• Martha Himmelfarb

  49 shared

• Peter Schäfer Geboren

  Jewish Museum Berlin

  49 shared

• Sarit Kattan

  Princeton University

  49 shared

• Ronald Perelman

  Association for Jewish Studies

  49 shared