About

Cary Nobles Robertson is an Associate Professor of Urology at Duke University. He is affiliated with the Duke Department of Urology, located at Duke South, 40 Medicine Circle, Durham, NC. His professional roles include involvement in the Urology Residency Program and the Duke Urologic Oncology Fellowship, indicating a focus on urologic oncology and surgical training. His contact email is cary.robertson@duke.edu, and he is engaged in research and education within the department. The page does not provide additional details about his research focus, background, or key contributions.

Research topics

• Internal medicine
• Medicine
• Computer Science
• Radiology
• Artificial Intelligence
• Surgery
• Cardiology
• Psychiatry
• Family medicine
• Medical physics
• Anesthesia

Selected publications

• Comparative Economic Evaluation of Radical Prostatectomy, Radiation, and Ablative Techniques in the Management of Localized Prostate Cancer

  Preprints.org · 2025-08-18

  preprintOpen access

  Background: To compare the costs of open retropubic radical prostatectomy (RRP), robotic-assisted radical prostatectomy (RALP), intensity-modulated radiation therapy (IMRT), low-dose brachytherapy (LDBT), stereotactic body radiotherapy (SBRT), cryotherapy (Cryo), and high-intensity focused ultrasound (HIFU) for low/intermediate-risk prostate cancer (PCa), from the healthcare system perspective. Methods: This retrospective, IRB-approved study compared the costs and charges of primary treatment options for localized PCa at Duke University Hospital between January 2018 and December 2019. Case identification was carried out by querying the relevant disease, procedural, and charge codes from Duke Finance. Consecutive cases with NCCN high-risk disease, prior treatment, or missing institutional financial information were excluded. Costs were calculated from the point at which the treatment option was selected until the last treatment session (SBRT and IMRT) or hospital discharge (other modalities). All modalities except RRP were considered technology-intensive. Results: A total of 552 patients with a mean age of 65.0 years met the inclusion criteria. NCCN risk categories included 85 (13%) low, 218 (41%) favorable-intermediate, and 249 (46%) unfavorable-intermediate risk cases. RALP, RRP, Cryo, and HIFU were single-session treatments, whereas IMRT, SBRT, and LDBT were delivered over multiple sessions. IMRT and SBRT were the most expensive modalities, followed by RALP, HIFU, LDBT, Cryo, and RRP. The number of sessions (ρ=0.55, p<0.001) and being technology-intensive (ρ=0.58, p<0.001) were significantly correlated with treatment costs. Conclusions: In this cohort of PCa patients, treatment costs were highest for IMRT and SBRT, followed by RALP, HIFU, LDBT, Cryo, and RRP. The number of treatment sessions significantly correlated with increased costs.

  PublisherOA PDFDOI

• MP04-18 ECONOMIC EVALUATION OF OPEN AND ROBOTIC RADICAL PROSTATECTOMY, RADIATION THERAPY, AND ABLATIVE SURGICAL TECHNIQUES IN THE MANAGEMENT OF LOW-TO-INTERMEDIATE RISK PROSTATE CANCER

  The Journal of Urology · 2025-04-08

  article
  PublisherDOI

• External validation of inter-reader reliability of the Prostate Imaging after Focal Ablation (PI-FAB) scoring system following focal cryoablation and focal high-intensity focused ultrasound

  European Radiology · 2025-04-02 · 2 citations

  article
  PublisherDOI

• Systematic Review and Meta-Analysis of Salvage Ablation for Radiation-Recurrent Localized Prostate Cancer – A Focal Therapy Society Project

  SSRN Electronic Journal · 2024-01-01

  preprintOpen access
  PublisherDOI

• Design of Payment and Reimbursement Strategies for Focal Therapy for Acceptance in Value-Based Care Models

  2024-01-01

  book-chapter
  PublisherDOI

• Primary Whole-gland Ablation for the Treatment of Clinically Localized Prostate Cancer: A Focal Therapy Society Best Practice Statement

  European Urology · 2023-07-05 · 40 citations

  reviewOpen access
  PublisherOA PDFDOI

• MP73-13 MRI ANALYSIS OF PROSTATE MORPHOMETRY AND PERIPROSTATIC ANATOMICAL RELATIONSHIPS BEFORE AND AFTER PARTIAL HIGH-INTENSITY FOCUSED ULTRASOUND TREATMENT OF LOCALIZED PROSTATE CANCER.

  The Journal of Urology · 2023-03-23

  article

  You have accessJournal of UrologyCME1 Apr 2023MP73-13 MRI ANALYSIS OF PROSTATE MORPHOMETRY AND PERIPROSTATIC ANATOMICAL RELATIONSHIPS BEFORE AND AFTER PARTIAL HIGH-INTENSITY FOCUSED ULTRASOUND TREATMENT OF LOCALIZED PROSTATE CANCER. Denis Seguier, Srinath Kotarmarti, Zoe Michael, Rajan Gupta, Cary Robertson, Thomas Polascik, Jonathan Olivier, and Arnauld Villers Denis SeguierDenis Seguier More articles by this author , Srinath KotarmartiSrinath Kotarmarti More articles by this author , Zoe MichaelZoe Michael More articles by this author , Rajan GuptaRajan Gupta More articles by this author , Cary RobertsonCary Robertson More articles by this author , Thomas PolascikThomas Polascik More articles by this author , Jonathan OlivierJonathan Olivier More articles by this author , and Arnauld VillersArnauld Villers More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003341.13AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Little is known regarding anatomical changes to peri-prostatic tissues after focal high intensity focused ultrasound (fHIFU) for localized prostate cancer. We sought to provide a novel approach to assess prostato-pelvic anatomical morphometric magnetic resonance imaging (MRI) changes post- fHIFU. METHODS: 38 patients (Pts) over two institutions (Lille University Hospital and Duke University Hospital) undergoing fHIFU with pre-and post-treatment (Pre-/Post-Tx) (≥6 months) MRI were included. Pre- and post-TX. MRIs were assessed for prostate and treated region volume. Distances to pubic bone and rectum were measured to account for the post-Tx periprostatic changes. Two subgroups were also identified, those with recurrence (positive biopsy and/or subsequent whole gland Tx) and those recurrence-free. Specific MRI features were also described within those two groups. RESULTS: The median treated-lobe volume was of 16.8 ml (IQR 10.6-21.5) on pre-Tx MRI and of 10.2 ml on post-Tx MRI (IQR 7.2-14.8). Comparison on pre-Tx MRI vs. post-Tx MRI showed a significant difference (p<0.01). The median percentage reduction of treated lobe volume for the entire cohort was 28.5% (IQR: 17-47). No significant difference was identified between the non-recurring group and the recurring group for prostate volume and treated lobe-volume both at pre- and post-Tx. Analysis of prostato-rectal measurements was conducted in 17 Pts. The mean value of the median prostato-rectal distance was 2 mm (SD 1) in pre-Tx and 1.97 mm (SD 1.1) in post-Tx. We noted no significant difference in either the pre-Tx or post-Tx configuration (p=0.78 and p=0.1 respectively) between the groups of recurring vs. non-recurring Pts. 13 Pts were qualitatively classified as presenting an aspect of loss of symmetry in the prostato-rectal space on post-Tx MRI. No significative difference existed between the recurring and non-recurring group for this parameter. CONCLUSIONS: With this study, we described a novel standardized method of morphometric alteration post-fHIFU. This preliminary work incite further studies to assess the clinical significance and implications of these results in a larger prospective cohort. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1040 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Denis Seguier More articles by this author Srinath Kotarmarti More articles by this author Zoe Michael More articles by this author Rajan Gupta More articles by this author Cary Robertson More articles by this author Thomas Polascik More articles by this author Jonathan Olivier More articles by this author Arnauld Villers More articles by this author Expand All Advertisement PDF downloadLoading ...

  PublisherDOI

• Molecular biomarkers in the context of focal therapy for prostate cancer: recommendations of a Delphi Consensus from the Focal Therapy Society

  Minerva Urology and Nephrology · 2022 · 20 citations

  • Computer Science
  • Artificial Intelligence
  • Medicine

  article: Molecular biomarkers in the context of focal therapy for prostate cancer: recommendations of a Delphi Consensus from the Focal Therapy Society - Minerva Urology and Nephrology 2022 October;74(5):581-9 - Minerva Medica - Journals

  PublisherDOI

• Available evidence on HIFU for focal treatment of prostate cancer: a systematic review

  International braz j urol · 2022 · 69 citations

  • Medicine
  • Surgery
  • Radiology

  PURPOSE: Prostate cancer (PCa) is the second most common oncologic disease among men. Radical treatment with curative intent provides good oncological results for PCa survivors, although definitive therapy is associated with significant number of serious side-effects. In modern-era of medicine tissue-sparing techniques, such as focal HIFU, have been proposed for PCa patients in order to provide cancer control equivalent to the standard-of-care procedures while reducing morbidities and complications. The aim of this systematic review was to summarise the available evidence about focal HIFU therapy as a primary treatment for localized PCa. MATERIAL AND METHODS: We conducted a comprehensive literature review of focal HIFU therapy in the MEDLINE database (PROSPERO: CRD42021235581). Articles published in the English language between 2010 and 2020 with more than 50 patients were included. RESULTS: Clinically significant in-field recurrence and out-of-field progression were detected to 22% and 29% PCa patients, respectively. Higher ISUP grade group, more positive cores at biopsy and bilateral disease were identified as the main risk factors for disease recurrence. The most common strategy for recurrence management was definitive therapy. Six months after focal HIFU therapy 98% of patients were totally continent and 80% of patients retained sufficient erections for sexual intercourse. The majority of complications presented in the early postoperative period and were classified as low-grade. CONCLUSIONS: This review highlights that focal HIFU therapy appears to be a safe procedure, while short-term cancer control rate is encouraging. Though, second-line treatment or active surveillance seems to be necessary in a significant number of patients.

  PublisherOA PDFDOI

• Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a prospective cohort study

  British Journal of Anaesthesia · 2021 · 23 citations

  • Medicine
  • Internal medicine
  • Cardiology
  PublisherOA PDFDOI

Frequent coauthors

• Thomas J. Polascik

  Duke Medical Center

  94 shared

• Judd W. Moul

  Duke University

  73 shared

• Wendy Demark‐Wahnefried

  University of Alabama at Birmingham

  50 shared

• David F. Paulson

  United States Department of Veterans Affairs

  49 shared

• Leon Sun

  Jiangnan University

  43 shared

• David Albala

  42 shared

• W. Marston Linehan

  National Cancer Institute

  32 shared

• Philip Walther

  Vienna Center for Quantum Science and Technology

  32 shared