
Carolyn Bertozzi
· Baker Family Director of Sarafan ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology and of RadiologyStanford University · Chemistry
Active 1990–2026
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About
Carolyn Bertozzi is the Baker Family Director of Stanford ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences, and a Professor, by courtesy, of Chemical and Systems Biology and of Radiology at Stanford University. She completed her undergraduate degree in Chemistry from Harvard University in 1988 and her Ph.D. in Chemistry from UC Berkeley in 1993. After her postdoctoral work at UCSF in cellular immunology, she joined the UC Berkeley faculty in 1996. In June 2015, she joined Stanford University faculty and became the co-director and Institute Scholar at Sarafan ChEM-H. Her research interests span chemistry and biology, with a focus on cell surface glycosylation related to disease states. Her lab studies changes in cell surface glycosylation associated with cancer, inflammation, and bacterial infection, aiming to develop diagnostic and therapeutic approaches, especially in immuno-oncology. She has received numerous honors and awards for her research and teaching, including membership in the National Academy of Sciences, the American Academy of Arts and Sciences, and the German Academy of Sciences Leopoldina, as well as awards such as the Nobel Prize in Chemistry, MacArthur Fellowship, and others.
Research topics
- Biology
- Cell biology
- Biochemistry
- Immunology
- Genetics
- Computational biology
- Chemistry
- Medicine
- Internal medicine
- Cancer research
Selected publications
Nature Neuroscience · 2020 · 1326 citations
Lysosome-targeting chimaeras for degradation of extracellular proteins
Nature · 2020 · 1077 citations
Senior authorCorrespondingSmall RNAs are modified with N-glycans and displayed on the surface of living cells
Cell · 2021 · 594 citations
Senior authorCorrespondingLYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
Nature Chemical Biology · 2021 · 568 citations
Senior authorCorrespondingTargeted glycan degradation potentiates the anticancer immune response in vivo
Nature Chemical Biology · 2020 · 350 citations
Senior authorCorresponding
Recent grants
Glycosylation and Immune Evasion in Urologic Tumors
NIH · $3.0M · 2019–2026
NIH · $6.2M · 2018
NIH · $6.0M · 2016
Frequent coauthors
- 147 shared
Nicholas M. Riley
University of Washington
- 98 shared
Stacy A. Malaker
Yale University
- 97 shared
Laura L. Kiessling
Massachusetts Institute of Technology
- 95 shared
Julie A. Leary
University of California, Davis
- 88 shared
David Rabuka
- 87 shared
Joseph A. Loo
University of California, Los Angeles
- 85 shared
Gilbert C. Walker
University of Toronto
- 85 shared
William L. Jorgensen
Yale University
Education
- 1988
B.S.
Harvard University
- 1993
Ph.D.
UC Berkeley
Awards & honors
- Nobel Prize in Chemistry
- Lemelson-MIT award for inventors
- Whistler Award
- Ernst Schering Prize
- MacArthur Foundation Fellowship
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