
Carla Falcon
· Associate ProfessorVerifiedRutgers University · Endodontics
Active 2019–2025
Research topics
- Dentistry
- Medicine
- Computer Science
- Information Retrieval
- Orthodontics
- Database
- Anatomy
- Endocrinology
- Physical therapy
- Materials science
- Anesthesia
- Internal medicine
- Surgery
Selected publications
Imaging of Odontogenic Pain—Homotopic/Primary
2025-01-01
book-chapter1st authorCorrespondingJournal of Endodontics · 2025-10-08
article1st authorCorrespondingSystemic Factors Affecting Prognosis and Outcome of Endodontic Therapy
Dental Clinics of North America · 2024-07-09
review1st authorCorrespondingInternational Journal of Molecular Sciences · 2024-12-19 · 2 citations
articleOpen accessPatients with diabetes mellitus (DM) have an increased risk of tooth decay caused by alterations in their tooth development and their oral environment, as well as a tendency to present with pulp infection due to compromised immune response. The present study analyzed the characteristic alterations in tooth development under DM conditions using incisors from db/db type 2 diabetic mouse model (T2DM mice). In micro-CT analyses, T2DM mice showed delayed dentin and enamel formation. Through transcriptomic analyses, pre-ameloblast- and pre-odontoblast-specific genes were found to be significantly decreased in the incisors of T2DM mice, whereas major ameloblast- and mature odontoblast-specific genes were not changed. Stem cell markers were decreased in T2DM mice compared to those from the control mice, suggesting that the stemness of dental pulp cells (DPCs) is attenuated in T2DM mice. In vitro analyses demonstrated that DPCs from T2DM mice have lower colony-forming units (CFU), slower propagation, and diminished differentiation characteristics compared to the control. These data suggest that T2DM conditions could impair the differentiation property of multiple progenitor/stem cells in the tooth, resulting in delayed tooth development in T2DM mice.
2022-03-13
articleThe present research aimed to assess if the teaching of the Yupana using the Tawa Pukllay method developed by Prem [16] enables to develop the computational thinking (CT) in children of 10 and 11 years old. For this purpose, a quasi-experiment with 52 children of two elementary schools located in Lima, Peru was performed. The obtained results were statistically significant showing that the experimental group, comprised with the students who were trained with the Yupana improved their CT compared to the control group, in which the students kept doing their regular activities. This highlights the fact that using this ancestral math tool could serve as an instrument to develop the CT in children.
Postendodontic pain: a practical approach to diagnosis and management.
Quintessence International · 2021 · 8 citations
- Medicine
- Dentistry
- Physical therapy
OBJECTIVES: Endodontic treatment is a routine procedure performed by general dental practitioners and endodontists on a daily basis. Fortunately, most patients undergoing endodontic therapy show a favorable outcome with uneventful healing. However, some patients develop pain following endodontic therapy. A majority of these patients develop acute, nociceptive pain ("flare-up") that resolves with appropriate treatment and subsequent healing. The dental profession is very adept at successfully managing the acute pain that occurs early following endodontic treatment. A minority of patients, however, develop ongoing pain following root canal therapy, termed chronic if persisting for 3 months or more. The diagnosis and management of chronic postendodontic pain are often challenging. This article aims to review pain following endodontic therapy, ranging from acute to chronic pain and its management, with specific emphasis on chronic pain, its pathophysiology, clinical features, diagnostic criteria, and management modalities. CONCLUSION: Endodontic treatment rarely leads to chronic neuropathic pain; however, when the nerve injury occurs and results in posttraumatic trigeminal neuropathic pain (PTNP), treatment options are very limited and rarely successful. Therefore, all steps should be taken to avoid nerve injury. Prevention of endodontic treatment related PTNP is crucial and achieved through early recognition, and prompt management.
Altered Prevalence of Pulp Diagnoses in Diabetes Mellitus Patients: A Retrospective Study
Journal of Endodontics · 2021 · 19 citations
- Medicine
- Dentistry
- Internal medicine
INTRODUCTION: Diabetes mellitus (DM) is a complex multisystemic disorder that affects an estimated 21 million Americans. No studies have evaluated the association of DM with the prevalence of each pulpal diagnosis. The objective of this study was to compare the prevalence of each pulp diagnosis including symptomatic irreversible pulpitis (SIP), asymptomatic irreversible pulpitis, reversible pulpitis, normal pulp, and pulp necrosis (PN) in DM patients against a nondiabetic control group. METHODS: A retrospective chart review was approved by Rutgers University Institutional Review Board. The prevalence of the diagnoses SIP, asymptomatic irreversible pulpitis, reversible pulpitis, normal pulp, and PN was calculated from AxiUm (Exan software, Las Vegas, NV) electronic health records at Rutgers School of Dental Medicine. The chi-square test was used to see the relationship between the 2 categoric variables. Second, binary logistic regression analyses were performed for each group. RESULTS: A total of 2979 teeth were diagnosed with a pulp condition between April 2013 and November 2018. The total tooth number of DM patients was 682, whereas the tooth number of nondiabetic patients was 2297. In the subgroup of patients younger than 40 years old, SIP was notably more prevalent in DM patients. In addition, the prevalence of PN in elderly DM patients (60-69 years old) was significantly higher than in the control group. CONCLUSIONS: The prevalence of SIP in DM patients was significantly higher compared with the control group (<40 years old), suggesting the possibility that DM could hypersensitize the subgroup of patients younger than 40 years old to pulpitis pain.
Factors Associated with Incomplete Endodontic Care
Journal of Endodontics · 2021 · 2 citations
1st authorCorresponding- Medicine
- Dentistry
- Orthodontics
Journal of Endodontics · 2021
- Information Retrieval
- Computer Science
- Information Retrieval
Chamberless Endodontic Access for Treatment of Calcified Anterior Central Incisors
Journal of Endodontics · 2020 · 5 citations
- Medicine
- Dentistry
- Orthodontics
Frequent coauthors
- 5 shared
Craig Hirschberg
Rutgers, The State University of New Jersey
- 4 shared
Paul Falcon
- 3 shared
Yi Ye
West China Medical Center of Sichuan University
- 3 shared
Yi Ye
Center for Excellence in Molecular Cell Science
- 2 shared
Anu Priya Guruswamy Pandian
Ragas Dental College & Hospital
- 2 shared
Yoshifumi Kobayashi
Rutgers, The State University of New Jersey
- 2 shared
Emi Shimizu
Rutgers, The State University of New Jersey
- 2 shared
Daniel H. Fine
Rutgers, The State University of New Jersey
Labs
EndodonticsPI
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