About

Anna Gibson is an Assistant Professor and Coordinator of the Introduction to Humanities & Social Sciences course at the College of Humanities and Social Sciences at NC State University. Her research focuses on the literature and culture of the long nineteenth century, with particular emphasis on the Victorian novel and its relationship to cultural and social life. She is interested in narrative form, especially how it has shaped psychological and cultural theories of human identity and relationships. Dr. Gibson is the co-director of the Digital Dickens Notes Project, an NEH-funded scholarly edition exploring Charles Dickens's working notes to demonstrate the serial unfolding of his novels and the dynamic networks of interaction they facilitate. She is also the principal investigator for a grant to complete this project and is working on a co-authored book about Dickens's serial composition, examining how material formats and temporal parameters of serial publication influenced the form of the novel. Her scholarly work includes a focus on Victorian literature, nineteenth-century British fiction, narrative form, and digital humanities. Dr. Gibson earned her M.A. from Exeter University in the UK and her Ph.D. from Duke University in 2014. She has previously served as a faculty member at Duquesne University before joining NC State in 2018. She has been recognized for her teaching excellence, being inducted into the NC State Academy of Outstanding Teachers in 2023 and receiving both the NC State Outstanding Teacher Award and the Alumni Association Outstanding Teacher Award. Her academic interests also encompass the history of psychology, visual culture, and critical theory.

Research topics

• Artificial Intelligence
• Computer Science
• Engineering
• Software engineering
• Machine Learning
• Engineering management
• Political Science
• Systems engineering
• Data science
• Archaeology
• History
• Engineering ethics

Selected publications

• P029: Initial psychometric evaluation of the adult symptom severity and impacts scale (PKU-SSIS) using interim data from the OPAL study

  Genetics in Medicine Open · 2025-01-01

  articleOpen access

  B4GALNT3 were associated with increased ALP levels.These findings demonstrate that rare, high-impact variants in genes other than ALPL can bi-directionally influence ALP levels.Conclusion: Our UK Biobank analyses reinforce the strong association of pathogenic ALPL variants and persistently low ALP levels.However, the HPP penetrance of heterozygous hypomorphic ALPL variants, particularly c.571G>A, may be lower than previously reported.This observed lower penetrance may explain why the highly prevalent c.571G>A heterozygous genotype has low frequency in HPP patient cohorts, such as the Global HPP Registry (4.4% of participants).Our rare variant analyses identified additional genetic contributors to ALP levels, expanding on prior common variant analyses, and underscore the polygenic nature of ALP regulation.Future studies should aim to refine HPP penetrance estimates for pathogenic ALPL variants, and to elucidate the contributions of non-ALPL variants to persistently low ALP and HPP.

  PublisherOA PDFDOI

• Electric-charge-dependent directed flow splitting of produced quarks in Au+Au collisions

  Physics Letters B · 2025-01-17

  articleOpen access

  We report directed flow ( v 1 ) of multistrange baryons (Ξ and Ω) and improved v 1 data for K − , p ¯ , Λ ¯ and ϕ in Au+Au collisions at s NN = 27 and 200 GeV from the STAR experiment at the Relativistic Heavy Ion Collider (RHIC). We focus on particles whose constituent quarks are not transported from the incoming nuclei but instead are produced in the collisions. At intermediate impact parameters, we examine quark coalescence behavior for particle combinations with identical quark content, and search for any departure from this behavior (“splitting”) for combinations having non-identical quark content. Under the assumption of quark coalescence for produced quarks, the splitting strength appears to increase with the electric charge difference of the constituent quarks in the combinations, consistent with electromagnetic effect expectations.

  PublisherDOI

• Hyperon global polarization in isobar Ru+Ru and Zr+Zr collisions at <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si15.svg"> <mml:mrow> <mml:msqrt> <mml:msub> <mml:mi>s</mml:mi> <mml:msub> <mml:mrow/> <mml:mrow> <mml:mrow> <mml:mi mathvariant="normal">N</mml:mi> </mml:mrow> <mml:mi>N</mml:mi> </mml:mrow> </mml:msub> </mml:msub> </mml:msqrt> <mml:mo linebreak="goodbreak">=</mml:mo> <mml:mn>200</mml:mn> <mml:mrow> <mml:mrow> <mml:mi mathvariant="normal">G</mml:mi> </mml:mrow> <mml:mi>e</mml:mi> <mml:mi>V</mml:mi> </mml:mrow> </mml:mrow> </mml:math>

  Physics Letters B · 2025-10-01 · 2 citations

  articleOpen access

  The polarization of Λ , Λ ¯ , Ξ − , and Ξ ¯ + hyperons along the angular momentum of the system has been measured in isobar collisions of Ru+Ru and Zr+Zr at s N N = 200 GeV with the STAR detector at RHIC. The polarization dependence on collision centrality exhibits an increasing trend in more peripheral collisions. Λ and Λ ¯ polarization dependence on the transverse momentum and pseudorapidity have been investigated, but no significant dependence was observed. The polarizations of Λ and Λ ¯ are found to be consistent with each other, indicating little contribution of the spin-magnetic coupling to the measured polarization. Comparison to previously measured polarization in Au+Au collisions show no obvious system size dependence.. The results are qualitatively consistent with hydrodynamic calculations including contributions from shear-induced polarization and thermal vorticity. For the first time in heavy-ion collisions, the dependence of the global polarization on the hyperon’s emission azimuthal angle relative to the second-order event plane has been measured, indicating stronger polarization for the in-plane emitted hyperons at the level of 2.4 σ significance in 20-50% centrality. The Ξ hyperon polarization measurements via polarization transfer analysis yield finite positive values with 2.9 σ significance in 20-50% centrality, slightly larger compared to the inclusive Λ polarization.

  PublisherDOI

• Determination of output factor for CyberKnife using scintillation dosimetry and deep learning

  Physics in Medicine and Biology · 2024-01-05 · 2 citations

  articleOpen accessSenior authorCorresponding

  Abstract Objective . Small-field dosimetry is an ongoing challenge in radiotherapy quality assurance (QA) especially for radiosurgery systems such as CyberKnife TM . The objective of this work is to demonstrate the use of a plastic scintillator imaged with a commercial camera to measure the output factor of a CyberKnife system. The output factor describes the dose on the central axis as a function of collimator size, and is a fundamental part of CyberKnife QA and integral to the data used in the treatment planning system. Approach . A self-contained device consisting of a solid plastic scintillator and a camera was build in a portable Pelicase. Photographs were analysed using classical methods and with convolutional neural networks (CNN) to predict beam parameters which were then compared to measurements. Main results . Initial results using classical image processing to determine standard QA parameters such as percentage depth dose (PDD) were unsuccessful, with 34% of points failing to meet the Gamma criterion (which measures the distance between corresponding points and the relative difference in dose) of 2 mm/2%. However, when images were processed using a CNN trained on simulated data and a green scintillator sheet, 92% of PDD curves agreed with measurements with a microdiamond detector to within 2 mm/2% and 78% to 1%/1 mm. The mean difference between the output factors measured using this system and a microdiamond detector was 1.1%. Confidence in the results was enhanced by using the algorithm to predict the known collimator sizes from the photographs which it was able to do with an accuracy of less than 1 mm. Significance . With refinement, a full output factor curve could be measured in less than an hour, offering a new approach for rapid, convenient small-field dosimetry.

  PublisherOA PDFDOI

• Advanced imaging to recover illegible text in historic documents. The challenge of past chemical treatments for ink enhancement

  Journal of Cultural Heritage · 2024-07-01 · 6 citations

  articleOpen access

  From fires to floods, from invisible inks to redactions, information has been accidentally or intentionally obscured on countless documents, maps and photographs, in collections from archives, libraries, and museums across the world. Removed from catalogues and reading rooms and therefore inaccessible to researchers and the general public, what new knowledge would these obscured documents reveal if we were able to read them? This paper demonstrates that current imaging technologies can be used to unlock this lost content. We used High Resolution Multiband Imaging (MBI), Reflectance Imaging Spectroscopy (RIS) and micro X Ray Fluorescence (µXRF) imaging to reveal illegible letter-forms and whole words written in iron gall ink on parchment from medieval documents relevant to the 'Virtual Record Treasury of Ireland' project, a digital reconstruction of archives destroyed in 1922 at the Public Record Office of Ireland at the outset of the Irish Civil War. The readability of text in historic documents with faded iron gall ink and/or parchment obscured by damp stains and ingrained dirt was successfully enhanced with MBI techniques, such as UV-induced visible luminescence (UVL) and UV reflected (UVR) imaging, which were able to recover the contrast of the ink. However, visualising text in documents showing chemical damage caused by the application of reagents for ink enhancement in the 19th century (a practice known as “galling”) was more challenging because of the similar composition of the ink and the staining. RIS proved helpful to read documents with moderate to severe chemical damage, particularly after applying Principal Component Analysis (PCA). Text in documents that were severely damaged by galling was also recoverable with µXRF imaging of the distribution of iron from the ink. This also posed several challenges, such as minimising movement of the parchment during overnight scans and separating the data corresponding to iron on the front of the parchment which was combined with the signal from the back. Through subtraction of elemental maps during post-processing, we managed to tackle the latter issue. The combination of these different imaging techniques enabled palaeographers and medieval records specialists to identify individual characters and whole words, thereby recovering the meaning of texts that were previously indecipherable. Further research will adapt the methodology to the broad range of causes of information loss, including other reagents historically used for ink enhancement, as well as the variety of document media and temporalities, which require an extensive and multi-faceted approach of advanced imaging and post-processing techniques, in balance with the preservation needs of these fragile and invaluable historic materials.

  PublisherDOI

• 159: Measurement of output factor for Cyberknife using scintillation dosimetry and deep learning

  Radiotherapy and Oncology · 2024-05-01

  articleSenior author
  PublisherDOI

• Agile Workforce Planning

  2024-04-30 · 3 citations

  book-chapter1st authorCorresponding

  Abstract Since its inception in 2017, agile workforce planning has rapidly developed as a leading practice to respond to the challenges of workforce planning in the real world. It is designed to be applicable in all businesses, in all industry sectors, and across all planning horizons. This chapter summarizes the agile workforce planning methodology for new and existing workforce planning practitioners. The chapter highlights the limitations of traditional approaches, lays out the principles of the approach, and steps through the methodology using multipart business case studies. Throughout the chapter, specific callouts are made to the experiences of a new practitioner in the workforce planning field.

  PublisherDOI

• HTA171 The Use of Qualitative Methods in the NICE HST Deliberative Process

  Value in Health · 2023-12-01

  article1st authorCorresponding
  PublisherDOI

• IPERION HS D6.3 Final report on innovation, exploitation and interoperability

  Zenodo (CERN European Organization for Nuclear Research) · 2023-04-20

  reportOpen access1st authorCorresponding

  This deliverable addresses the complex interactions of innovation, exploitation and interoperability in IPERION HS and their contributions to E-RIHS. It is based on work carried out in T6.1 (Innovation), T6.3 (Interoperability) and T6.4 (Exploitation) and draws heavily on the interim deliverables produced by those Tasks. The information was obtained by carrying out surveys, interviews, examination of previous publications and by the development of a data management plan. The work was carried out to support IPERION HS, but here we also examine the implications for E-RIHS ERIC. The main conclusion is that Heritage Science and E-RIHS exists within its own ecosystem, but to maximise its impact, it needs to engage with a wide range of other, related interests. This involves engaging with new user groups and collaborating with companies as well as recognising innovative training and outreach efforts, and ensuring that data is acquired and stored in a way that allows it to be shared with other users. As the visibility of Heritage Science increases, new user communities may arise, and significant government spending departments such as defence, healthcare, transport, and international development may start showing interest in Heritage Science. E-RIHS needs to be ready to respond to these changes, as well as to evolving international legislation and best practices in open data, open science, and intellectual property by updating policies frequently. Heritage Science needs to seek out new developments in other areas of science, technology, and industry that could have applications in Heritage Science. Similarly, the Heritage Science community needs to work with industry to exploit developments made in Heritage Science for maximum impact. The broad range of technologies, datatypes, and manufacturers found in Heritage Science makes open and FAIR data particularly challenging. E-RIHS can guide the Heritage Science community in developing a shared understanding of open data, which could contribute significantly to broader areas of science.

  PublisherDOI

• Medical imaging applied to heritage

  British Journal of Radiology · 2023-09-26 · 5 citations

  reviewOpen access1st authorCorresponding

  The use of imaging has transformed the study of cultural heritage artefacts in the same way that medical imaging has transformed medicine. X-ray-based techniques are common in both medical and heritage imaging. Optical imaging, including scientific photography and spectral imaging techniques, is also common in both domains. Some common medical imaging methods such as ultrasound and MRI have not yet found routine application in heritage, whereas other methods such as imaging with charged and uncharged particles and 3D surface imaging are more common in heritage. Here, we review the field of heritage imaging from the point of view of medical imaging and include some classic challenges of heritage imaging such as reading the text on burnt scrolls, identifying underdrawings in paintings, and CT scanning of mummies, an ancient calculating device and sealed documents. We show how hyperspectral imaging can offer insight into the drawing techniques of Leonardo da Vinci and explain how laparoscopy has identified the method of construction of a 500-year-old pop-up anatomical text book.

  PublisherDOI

Frequent coauthors

• Jeremy C. Hebden

  University College London

  77 shared

• Nick Everdell

  University College London

  43 shared

• Simon Arridge

  40 shared

• Topun Austin

  Cambridge University Hospitals NHS Foundation Trust

  34 shared

• Gary Royle

  University College London

  22 shared

• David T. Delpy

  University College London

  22 shared

• Robert J. Cooper

  University of Georgia

  21 shared

• Martin Schweiger

  King's College London

  20 shared

Labs

• Research and EngagementPI

Awards & honors

• NC State Academy of Outstanding Teachers (2023)
• NC State Outstanding Teacher Award
• NC State Alumni Association Outstanding Teacher Award
• Honorable Mention, Donald Gray Prize for Best Essay in Victo…