Ann Hsing

About

Ann Hsing is a professor of medicine at Stanford University and a senior fellow for the Center for Innovation in Global Health. She has conducted population-based epidemiological studies across four continents, including North and South America, Asia, Africa, and Europe. Her expertise encompasses the epidemiology and etiology of prostate, hepatobiliary, and thyroid cancers, as well as hormonal carcinogenesis and circadian rhythm. With over 22 years of experience at the National Cancer Institute, Dr. Hsing has developed extensive expertise in molecular epidemiology, global oncology, cancer prevention, and population-based studies in international settings. She has served on numerous committees and advisory boards, including as a member of the Editorial Board of Cancer Epidemiology, Biomarkers & Prevention and as an academic editor of PLOS ONE. Dr. Hsing has authored more than 340 peer-reviewed articles, written seven book chapters, and mentored over 65 post-doctoral fellows and scholars. Her current research projects include longitudinal studies on well-being across multiple countries, investigations into liver cancer patterns and trends, and studies on non-viral factors of liver cancer, as well as the clinical utility of ctNDA in liver cancer surveillance. She also leads a genome-wide association study of prostate cancer in African countries and utilizes big data resources to inform clinical practice.

Research topics

• Medicine
• Internal medicine
• Oncology
• Genetics
• Environmental health
• Biology
• Political Science
• Pathology
• Virology
• Demography

Selected publications

• Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

  Nature Genetics · 2021 · 489 citations

  Prostate cancer is a highly heritable disease with large disparities in incidence rates across ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer genome-wide association studies (107,247 cases and 127,006 controls) and identified 86 new genetic risk variants independently associated with prostate cancer risk, bringing the total to 269 known risk variants. The top genetic risk score (GRS) decile was associated with odds ratios that ranged from 5.06 (95% confidence…

  DOI

• High Prevalence of Concurrent Gastrointestinal Manifestations in Patients With Severe Acute Respiratory Syndrome Coronavirus 2: Early Experience From California

  Gastroenterology · 2020 · 218 citations

  DOI

• Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

  Nature Genetics · 2023 · 135 citations

  The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry genome-wide association study of 156,319 prostate cancer cases and 788,443 controls of European, African, Asian and Hispanic men, reflecting a 57% increase in the number of non-European cases over previous prostate cancer genome-wide association studies. We identified 187 novel risk…

  DOI

• Knowledge Gaps, Challenges, and Opportunities in Health and Prevention Research for Asian Americans, Native Hawaiians, and Pacific Islanders: A Report From the 2021 National Institutes of Health Workshop

  Annals of Internal Medicine · 2022 · 114 citations

  Asian Americans (AsA), Native Hawaiians, and Pacific Islanders (NHPI) comprise 7.7% of the U.S. population, and AsA have had the fastest growth rate since 2010. Yet the National Institutes of Health (NIH) has invested only 0.17% of its budget on AsA and NHPI research between 1992 and 2018. More than 40 ethnic subgroups are included within AsA and NHPI (with no majority subpopulation), which are highly diverse culturally, demographically, linguistically, and socioeconomically. However, data for t…

  DOI

• Distinct Gut Microbiota Profiles in Normal Weight Obesity and Their Association With Cardiometabolic Diseases: Results From Two Independent Cohort Studies

  Journal of Cachexia Sarcopenia and Muscle · 2024-12-26 · 17 citations

  articleOpen access

  BACKGROUND: Normal weight obesity (NWO) is characterized by excess body fat in individuals with normal body mass index (BMI). This study aimed to investigate gut microbiota alterations in NWO and their potential associations with cardiometabolic diseases (CMD) risk in two independent cohorts. METHODS: ) but an excess per cent body fat (PBF, ≥ 25% in men and ≥ 35% in women). Normal weight lean was defined as having a normal BMI and normal PBF. The 16S rRNA gene sequencing method was used to analy…

  PublisherOA PDFDOI

Recent grants

• Prostate Cancer Studies

  NIH · $9.9M

• Etiology of Biliary Tract Cancer

  NIH · $30.4M

• PLCO Trial Etiologic and Early Marker Study

  NIH · $29.9M

Frequent coauthors

• Stephen J. Chanock

  1209 shared

• Christopher A. Haiman

  1027 shared

• Brian E. Henderson

  1011 shared

• Demetrius Albanes

  1005 shared

• Michaël Pollak

  McGill University

  1001 shared

• Victoria L. Stevens

  Mayo Clinic in Arizona

  979 shared

• Fredrick R. Schumacher

  Case Western Reserve University

  972 shared

• Loı̈c Le Marchand

  Cancer Center of Hawaii

  961 shared

Awards & honors

• Member, American Epidemiological Society (2016)
• Fellow, American College of Epidemiology
• NIH, Merit Award
• NIH, Mentoring Award
• NIH, Women in Science Monograph

Similar researchers at Stanford University

• Jon A. Krosnickh-95
• Robert Weisbergh-77
• Douglas McAdamh-70