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Andrew Gene Kim

Andrew Gene Kim

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University of Illinois Urbana-Champaign · Department of Biomedical and Translational Sciences

Active 1988–2025

h-index41
Citations6.2k
Papers31871 last 5y
Funding$1.3M
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About

Andrew Gene Kim is a Clinical Assistant Professor in the Department of Clinical Sciences at the Carle Illinois College of Medicine, University of Illinois Urbana-Champaign. His contact email is agkim3@illinois.edu. The page does not provide specific details about his research focus, background, or key contributions.

Research topics

  • Nanotechnology
  • Materials science
  • Physics
  • Quantum mechanics
  • Condensed matter physics
  • Optoelectronics
  • Chemical physics

Selected publications

  • Body mass index and its association with clinical outcomes in acute liver failure

    World Journal of Clinical Cases · 2025-10-11 · 2 citations

    articleOpen access

    BACKGROUND: Acute liver failure (ALF) is a life-threatening multisystemic condition with high short-term mortality. With the growing prevalence of obesity and metabolic syndrome, it is important to investigate the clinical implications of high body mass index (BMI) on survival outcomes in ALF. AIM: To explore the impact of overweight and obesity on the clinical outcomes of patients with ALF. METHODS: A retrospective observational cohort study was conducted involving patients with ALF admitted to the Johns Hopkins Health System between January 1, 2000 and May 1, 2020. We performed Cox proportional hazards regression to identify outcomes, including the need for liver transplantation (LT) or all-cause mortality. RESULTS: = 0.008) than among survivors. Patients with overweight and obesity had a higher risk of all-cause mortality or need for LT by 2.22-fold (95%CI: 1.30-3.78) and 2.04-fold (95%CI: 1.29-3.39), respectively. Elevated BMI was associated with renal failure and higher grades of hepatic encephalopathy. Derangements in serologic markers, including alanine transaminase, lactate, and ammonia, were associated with a mortality risk or need for LT. CONCLUSION: In this large, retrospective study, with a diverse cohort of United States patients, Overweight and obese were independently associated with an increased risk of all-cause mortality or need for LT. This work highlights the importance of closely monitoring ALF patients who are overweight or obese for adverse complications and measures to improve outcomes in this vulnerable patient population.

  • Pastoral Supervision on Sexual Issues in Ministry: A Psychodynamic Perspective

    Theological Forum · 2025-03-31

    article1st authorCorresponding

    목회자의 성 관련 이슈는 교회 내외에서 큰 파급력을 갖는다. 대개 목회자에게는 일반인들에게 부과되는 것보다 더욱 높은 도덕적, 윤리적 기준이 요청되기 때문에, 목회자가 성적인 이슈에 관련될 경우 해당 목회자 개인을 넘어 교계를 향한 강력한 비난이 뒤따르게 된다. 이와 같은 이유로 교계는 목회자의 성 관련 이슈를 언급하는 것 자체를 터부시하거나 이슈를 수면화하기보다는 축소하는 경향성을 보여 왔다. 이미 사회적으로 드러난 사건의 경우에는 해당 이슈가 목회자 개인의 문제에서 비롯되었다고 보며 개인적인 관점에서 해결책을 찾는 접근이 주류를 이룬다. 목회자가 성적 부정을 저지르는 것은 목회자가 윤리적으로 타락했기 때문이라고 보는 것이다. 조금 더 큰 틀에서 체계를 바라보는 관점에서는 목회자 성 이슈가 교회 안의 권력 구도, 힘의 차이에 연유한 것으로 해석하기도 하나, 해결 방안은 여전히 윤리적 접근에서 크게 달라지지 않는다. 본 논문은 목회자의 성 관련 이슈를 윤리적, 개인적 문제로 인식하는 점에 의문을 제기한다. 해당 접근이 그릇되었다기보다는 거시적으로 목회자, 상처입게 된 성도들이나 교회 공동체, 이들을 지켜보는 사회에 도움이 되지 않기 때문이다. 따라서 본 논문에서 필자는 목회자가 갖는 성 관련 이슈를 목회자 개인의 윤리적 타락으로 해석하고 처벌로 일괄하는 대신, 목회 수퍼비전을 제공하되 정신역동에 중점을 두어 접근하는 관점을 제시한다. 목회 수퍼비전은 목회자가 좋은 돌봄 제공자로 성장할 수 있도록 돕는 역할을 하며, 정신역동적 관점은 목회자와 성도 사이에 어떠한 일이 일어나고 있는지 더 잘 이해할 수 있도록 하여 실연을 예방하는 동시에 개인의 치유와 성장을 돕기 때문이다. 본 논문은 위와 같이 목회 수퍼비전을 통하여 목회자들이 성적 역동을 윤리적 타락의 증거이자 덫이 아닌 강력한 자원으로 사용할 수 있게 될 가능성을 제시한다.

  • A HIDDEN WING OF THE CHURCH : A STUDY ON THE PRACTICE AND THEOLOGIZING OF FEMALE MISSIONARIES WITH SPECIAL FOCUS ON THE LIFE OF CHUN, CHAE OK

    Muslim-Christian Encounter · 2025-09-30

    article1st authorCorresponding

    신학적 전통과 선교적 상황의 상이함에도 불구하고 여성들은 선교의 실천과 신학화의 현장에서 공통된 도전에 직면해 왔다. 그들의 의견이 존중받지 못하고, 헌신적인 사역에도 불구하고 그 정체와 역할을 인정받지 못함으로 인한 불분명한 소속감이 바로 그것이다.<br/> 이러한 여성 선교사들의 신학적 실천과 신학화를 조명하기 위해 한국 최초의 이슬람권 선교사였던 전재옥 전 이화여대 신학대학원의 삶과 신학을 분석하고자 한다.<br/>전재옥 선교사는 1961년 한국과 파키스탄의 외교 관계가 수립되기도 전에 한국 교회 최초의 이슬람권 여성 선교사로 파송 받아 1974년까지 헌신했다. 선교 사역을 마친 후에는 모교인 이화여대에서 30여 년 가까이 교수로 봉직하였다. 그 기간에 그녀는 세계선교학회장으로 선출되는 등 세계 선교 학계에서 아시아인 여성으로서의 정체성과 성찰이 담긴 선교 신학으로 세계 선교 신학계의 스펙트럼을 풍요롭게 하는 데 공헌하였다<br/> 전재옥 선교사의 삶을 통해 살펴보았듯이, 여성들의 선교 자리는 “고난과 비움, 그럼에도 불구하고 피워내는 생명과 아름다움”으로 특징 지을 수 있을 것이다.<br/> 그러므로 교회 안의 여성들이 자신의 형상을 따라 남자와 여자를 창조하신 하나님, 이 땅에서 다양한 상황에 놓여있던 여성들을 인격적으로 만나신 예수님과 진정한 자아와 능력을 발견할 수 있도록 고난 가운데서 격려하시는 성령님이 주시는 영감과 능력으로 자신의 전인적 경험과 성찰을 신학화할 수 있도록 격려해야 한다.

  • Mental health risks associated with a family history of chronic diseases: A nationwide population-based cross-sectional study

    Journal of Psychosomatic Research · 2025-08-05

    article1st authorCorresponding
  • Patchy nanoparticles by atomic stencilling

    Nature · 2025-10-15 · 15 citations

    articleOpen access1st author

    Abstract Stencilling, in which patterns are created by painting over masks, has ubiquitous applications in art, architecture and manufacturing. Modern, top-down microfabrication methods have succeeded in reducing mask sizes to under 10 nm (refs. 1,2 ), enabling ever smaller microdevices as today’s fastest computer chips. Meanwhile, bottom-up masking using chemical bonds or physical interactions has remained largely unexplored, despite its advantages of low cost, solution-processability, scalability and high compatibility with complex, curved and three-dimensional (3D) surfaces 3,4 . Here we report atomic stencilling to make patchy nanoparticles (NPs), using surface-adsorbed iodide submonolayers to create the mask and ligand-mediated grafted polymers onto unmasked regions as ‘paint’. We use this approach to synthesize more than 20 different types of NP coated with polymer patches in high yield. Polymer scaling theory and molecular dynamics (MD) simulation show that stencilling, along with the interplay of enthalpic and entropic effects of polymers, generates patchy particle morphologies not reported previously. These polymer-patched NPs self-assemble into extended crystals owing to highly uniform patches, including different non-closely packed superlattices. We propose that atomic stencilling opens new avenues in patterning NPs and other substrates at the nanometre length scale, leading to precise control of their chemistry, reactivity and interactions for a wide range of applications, such as targeted delivery, catalysis, microelectronics, integrated metamaterials and tissue engineering 5–11 .

  • Machine Learning-Based Multiplex Immunofluorescence Staining from Immunohistochemistry with Generative Adversarial Networks

    Journal of Student Research · 2025-02-28

    articleOpen access1st authorCorresponding

    Immunohistochemistry (IHC) and Immunofluorescence (IF) are the two most commonly employed methods of cell staining, which aims to enhance visibility of cellular components for medical research and diagnosis. Immunofluorescence which uses fluorescently labeled antibodies to detect specific proteins is preferred over immunohistochemistry for multiplexing and colocalization which analyze protein distributions due to its transparent nature. However access is often barred due to high costs of reagents and equipment, slide quality degradation overtime, and technical limitations such as autofluorescence, and background staining from non-specific binding or cross reactivity antibodies. To address the aforementioned issue, we propose a novel machine learning-based immunofluorescence staining approach utilizing Generative Adversarial Network (GAN). The model intakes a digital pathology image of IHC and converts it to an IF image through feature maps. The proposed model achieved state-of-art performance with PSNR value of 30.67 and SSIM value of 0.8992. Additionally, the qualitative experimental results demonstrate the efficacy of the proposed method in enhancing generating high-quality IF stained images.

  • Origins of suppressed self-diffusion of nanoscale constituents of a complex liquid

    arXiv (Cornell University) · 2024-04-27 · 1 citations

    preprintOpen access

    Understanding and ultimately controlling the transformations and properties of nanoscale systems, from proteins to synthetic nanomaterial assemblies, is limited by the inability to uncover their dynamics on their characteristic length and time scales. Here, we nevertheless demonstrate this ability using MHz X-ray photon correlation spectroscopy (XPCS) -- directly elucidating the characteristic microsecond-dynamics of density fluctuations of semiconductor nanocrystals (NCs), not only in a colloidal dispersion but also in a liquid phase consisting of densely packed, yet mobile, NCs with no long-range order. We find the wavevector-dependent fluctuation rates in the liquid phase are suppressed relative to those in the colloidal phase and relative to observations of densely packed repulsive particles. We show that the suppressed rates are due to a substantial decrease in the self-diffusion of NCs, which we attribute to explicit attractive interactions. Using coarse-grained simulations, we find that the extracted shape and strength of the interparticle potential explains the stability of the liquid phase, in contrast to the gelation observed via XPCS in many other charged colloidal systems. This work opens the door to elucidating fast, condensed phase dynamics in complex fluids and other nanoscale soft matter, such as densely packed proteins and non-equilibrium self-assembly processes, in addition to designing microscopic strategies to avert gelation.

  • Netflix Dilemma : A Study on the Transformation of the Korean Broadcasting Production System in the Platform Habitus Era

    Media & Society · 2024-05-31

    article1st authorCorresponding

    이 연구는 ‘플랫폼 아비투스’라는 개념을 통해 넷플릭스 이후 한국 방송영상 제작시스템에 어떠한 변화가 일어나고 있는지를 살펴본다. 글로벌 OTT가 제공하는 막대한 제작 자율성과 제작비는 한국 방송영상물의 질적 도약이라는 원리를 근간에 둔다. 이 점에서 제작자들은 여러 딜레마적 상황에 놓여 있다. 이 연구는 ‘방송한류’를 위시한 산업 규모나 수출액 검토에 집중하고 글로벌 OTT와의 협업을 낭만화하는 대신 생산자의 시선을 통해 제작현장의 변화를 읽어내고자 했다. 연구결과 지배적 행위자인 넷플릭스를 통해 영화 장의 유입이 두드러짐을 알 수 있었다. 펀드레이징부터 스태프 고용, 배급자 섭외를 총괄해온 영화 감독들의 풍부한 경험치, 티켓과 구독으로 비용을 지불할 만큼의 장르물을 만들어내는 영화 장의 고유한 특성이 넷플릭스와 합치됐다. 기술적 차원에서, 넷플릭스의 세분화된 제작 공정은 글로벌 표준 감각을 익힐 수 있는 기회로 부각됐다. 제작자들은 넷플릭스와 같은 대자본의 총량에 특화된 아비투스를 형성해 나가면서 ‘돈의 두께’만큼 콘텐츠IP의 양도를 인정했다. 한국 예능 고유의 특수성인 자막의 소거와 일상성의 소멸은 넷플릭스 젠트리피케이션의 일면이었다. 한국 콘텐츠의 투자 가능성과 전 세계 수익성은 양화된 데이터에 근간해 이미 계산된 것이나 다름 없었다. 넷플릭스의 데이터 권력은 제작시스템 변화의 동력으로 작용하면서 국내 제작자의 절합적 사고와 대안적 고민을 가로막는 요인이었다. 이러한 변화 과정은 전통적인 방송 장의 공공성 아비투스가 OTT라는 새로운 방송 장의 플랫폼 아비투스로 변화되는 징후로 읽을 수 있다.

  • Anion and Cation Migration at 2D/3D Halide Perovskite Interfaces

    ACS Energy Letters · 2024-05-14 · 32 citations

    articleOpen access

    This study explores the ionic dynamics in 2D/3D perovskite solar cells, which are known for their improved efficiency and stability. The focus is on the impact of halide choice in 3D perovskites treated with phenethylammonium halide salts (PEAX, X = Br and I). Our findings reveal that light and heat drive ionic migration in these structures, with PEA+ species diffusing into the 3D film in PEABr-treated samples. Mixed-halide 3D perovskites show halide interdiffusion, with bromine migrating to the surface and iodine diffusing into the film. Cathodoluminescence microscopy reveals localized 2D phases on the 3D perovskite, which become more evenly distributed after thermal treatment. Both PEAX salts enhance the performance of photovoltaic devices. This improvement is attributed to the passivation capabilities of the salts themselves and their respective Ruddlesden−Popper (RP) phases. Annealed PEAI-treated devices show a better balance between efficiency and statistical distribution of photovoltaic parameters.

  • Peptide-Bound Glycative, AGE and Oxidative Modifications as Biomarkers for the Diagnosis of Alzheimer’s Disease—A Feasibility Study

    Biomedicines · 2024-09-19 · 1 citations

    articleOpen access

    Background: The diagnosis of Alzheimer’s disease (AD) relies on core cerebrospinal fluid (CSF) biomarkers, amyloid beta (Aβ) and tau. As the brain is then already damaged, researchers still strive to discover earlier biomarkers of disease onset and the progression of AD. Glycation, advanced glycation end products (AGEs) and oxidative modifications on proteins in CSF mirror the underlying biological mechanisms that contribute to early AD pathology. However, analyzing free AGEs in the body fluids of AD patients has led to controversial results. Thus, this pilot study aimed to test the feasibility of detecting, identifying and quantifying differentially glycated, AGE or oxidatively modified peptides in CSF proteins of AD patients (n = 5) compared to a control group (n = 5). Methods: To this end, we utilized a data-dependent (DDA) nano liquid chromatography (LC) linear ion trap-Orbitrap tandem mass spectrometry (MS/MS) ) approach and database search that included over 30 glycative and oxidative modifications in four search nodes to analyze endogenous modifications on individual peptides. Furthermore, we quantified candidate peptide abundance using LC Quan. Results: We identified 299 sites of early and advanced glycation and 53 sites of oxidatively modified tryptophan. From those, we identified 17 promising candidates as putative biomarkers (receiver operating curve-area under the curve (ROC-AUC) &gt; 0.8), albeit without statistical significance. Conclusions: The potential candidates with higher discrimination power showed correlations with established diagnostic markers, thus hinting toward the potential of those peptides as biomarkers.

Recent grants

Frequent coauthors

  • Seong Ho Park

    Samsung (South Korea)

    152 shared
  • Hyun Kwon Ha

    149 shared
  • Tae Kyoung Kim

    Vanderbilt University Medical Center

    92 shared
  • Pyo Nyun Kim

    Ulsan College

    77 shared
  • Kyung Won Kim

    Asan Medical Center

    73 shared
  • Moon-Gyu Lee

    57 shared
  • Jae Ho Byun

    University of Ulsan

    55 shared
  • Joon Koo Han

    Seoul National University Hospital

    55 shared

Awards & honors

  • Carle Illinois College of Medicine Professorships, Awards, a…
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