Andreas H. Hielscher

About

Andreas H. Hielscher, Ph.D., is a Professor and Chair of the Department of Biomedical Engineering at New York University’s Tandon School of Engineering since July 1, 2020. He received his PhD degree in Electrical and Computer Engineering from Rice University in Houston, Texas, in 1995. Following his doctoral studies, Dr. Hielscher spent two years as a Postdoctoral Fellow at Los Alamos National Laboratory in New Mexico. He then joined the faculty at the State University of New York Downstate Medical Center in Brooklyn, New York. In September 2001, he moved to Columbia University in New York City, where he became the Director of the Biophotonics and Optical Radiology Laboratory and held appointments as Full Professor in the Departments of Biomedical Engineering, Electrical Engineering, and Radiology. Dr. Hielscher has made pioneering contributions in the field of Biomedical Optics. His current research focuses on the development of state-of-the-art imaging software and hardware for optical tomography. He applies this emerging technology to the imaging of cancer, peripheral artery disease (PAD) in diabetic patients, and joint diseases. Over the course of his career, he has published more than 200 articles in peer-reviewed scientific journals and conference proceedings. His work has been supported by various funding agencies including the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Heart, Lung, and Blood Institute (NHLB), the…

Research topics

• Computer Science
• Optics
• Computer vision
• Artificial Intelligence
• Physics
• Oncology
• Biology
• Pathology
• Internal medicine
• Medicine

Selected publications

• High Resolution, Deep Imaging Using Confocal Time-of-Flight Diffuse Optical Tomography

  IEEE Transactions on Pattern Analysis and Machine Intelligence · 2021 · 44 citations

  Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep within tissue - well beyond the conventional ∼ 10-15 mean scattering lengths tolerated by ballistic imaging techniques such as confocal and two-photon microscopy. Unfortunately, existing DOT systems are limited, achieving only centimeter-scale resolution. Further…

  DOI

• Ultrafast and Ultrahigh-Resolution Diffuse Optical Tomography for Brain Imaging with Sensitivity Equation based Noniterative Sparse Optical Reconstruction (SENSOR)

  Journal of Quantitative Spectroscopy and Radiative Transfer · 2021 · 16 citations

  Senior authorCorresponding
  DOI

• Changes in Diffuse Optical Tomography Images During Early Stages of Neoadjuvant Chemotherapy Correlate with Tumor Response in Different Breast Cancer Subtypes

  Clinical Cancer Research · 2021 · 11 citations

  Senior authorCorresponding

  PURPOSE: This study's primary objective was to evaluate the changes in optically derived parameters acquired with a diffuse optical tomography breast imaging system (DOTBIS) in the tumor volume of patients with breast carcinoma receiving neoadjuvant chemotherapy (NAC). EXPERIMENTAL DESIGN: In this analysis of 105 patients with stage II-III breast cancer, normalized mean values of total hemoglobin ([Formula: see text]), oxyhemoglobin ([Formula: see text]), deoxy-hemoglobin concentration ([Formula…

  DOI

• Preliminary Study Using Wearable Near-Infrared Spectroscopy for Continuous Monitoring of Hemodynamics Through the Carotid Artery

  Biosensors · 2025-08-20 · 1 citations

  articleOpen accessSenior author

  Non-invasive, continuous monitoring of carotid artery hemodynamics may provide valuable insights on cerebral blood perfusion (CBP). Near-infrared spectroscopy (NIRS) is a non-invasive modality that may be a good candidate for real-time carotid artery monitoring. We designed a wearable NIRS system to monitor the left and right radial and carotid arteries in 20 healthy subjects. The changes in total hemoglobin concentration (HbT) and tissue oxygen saturation (StO2) in all 80 arteries were continuo…

  PublisherOA PDFDOI

• Development of a patient-friendly optical imaging system for simultaneous monitoring arthritis in multiple finger joints of patients with systemic lupus erythematosus

  2024-01-26 · 1 citations

  articleSenior author

  We have developed an optical imaging system that allows monitoring arthritis in systemic lupus erythematosus (SLE) patients in multiple finger joints simultaneously. This system addresses the need for a low-cost accurate way to quickly assess SLE in a patient friendly manner. system comprises multiple flexible optical bands for each finger. Each band includes eight sets of three light-emitting-diodes (LEDs) (wavelength λ = 880 nm, 660 nm, and 530 nm) and a photodiode and can be wrapped ar…

  PublisherDOI

Recent grants

• Optical Tomographic Imaging of Peripheral Arterial Disease

  NIH · $2.5M · 2013–2019

• NIH Grant R21CA118666

  NIH · $240k · 2008

• NIH Grant R01AR046255

  NIH · $2.6M · 2010

Frequent coauthors

• Hyun Koo Kim

  86 shared

• Alessandro Marone

  New York University

  69 shared

• Dawn L. Hershman

  Columbia University Irving Medical Center

  66 shared

• Alexander D. Klose

  InVivo Analytics (United States)

  58 shared

• Kevin Kalinsky

  Emory University

  57 shared

• Uwe J. Netz

  Laser- und Medizin-Technologie (Germany)

  52 shared

• Molly Flexman

  Philips (United States)

  44 shared

• Hanina Hibshoosh

  42 shared

Education

• PhD, Electrical and Computer Engineering

  Rice University

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