Allen Chen

FRI-323 Redundant yet distinct role of Vacuole membrane protein 1 and transmembrane protein 41B in regulating hepatic lipoprotein secretion and autophagy in metabolic dysfunction-associated steatohepatitis

Journal of Hepatology · 2025-05-01

Natural products remodel cancer-associated fibroblasts in desmoplastic tumors

UNC Libraries · 2024-06-01

Desmoplastic tumors have an abundance of stromal cells and the extracellular matrix which usually result in therapeutic resistance. Current treatment prescriptions for desmoplastic tumors are usually not sufficient to eliminate the malignancy. Recently, through modulating cancer-associated fibroblasts (CAFs) which are the most abundant cell type among all stromal cells, natural products have improved chemotherapies and the delivery of nanomedicines to the tumor cells, showing promising ability t…

402 (PB390): Discovery of a Novel Covalent PAX8 Inhibitor

European Journal of Cancer · 2024-10-01

Comprehensive versus Less-than-Comprehensive Fields in the Radiotherapeutic Management of Unknown Primary Cancer of the Head and Neck

Clinical Imaging and Case Reports · 2024-05-23

Purpose : To compare clinical outcomes among patients treated with comprehensive and non-comprehensive radiation fields for squamous cell carcinoma of occult primary origin involving the cervical lymph nodes.

Comprehensive versus Less-than-Comprehensive Fields in the Radiotherapeutic Management of Unknown Primary Cancer of the Head and Neck

Clinical Imaging and Case Reports · 2024-05-23

Purpose To compare clinical outcomes among patients treated with comprehensive and non-comprehensive radiation fields for squamous cell carcinoma of occult primary origin involving the cervical lymph nodes.