About

Alfonse Cinotti, M.D., is a faculty member in the Department of Ophthalmology & Visual Science at Rutgers New Jersey Medical School. He earned his M.D. degree in 1946 from the State University of New York at Brooklyn. His professional focus is within the field of ophthalmology and visual science, contributing to the academic and clinical activities of the department. Further details about his research interests, key contributions, or specific areas of expertise are not provided in the available page content.

Research topics

• Medicine
• Ophthalmology
• Optometry
• Radiology
• Surgery

Selected publications

• Toxicological evaluation of gasolines by GC-MS analysis

  Chromatographia · 2001-01-01 · 3 citations

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• Extracorporeal lithotripsy of intrahepatic stones with associated strictures of intrahepatic biliary ducts.

  PubMed · 1998-12-01 · 5 citations

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  BACKGROUND AND AIMS: Intrahepatic stones are a frequent disease in the Eastern world but rare in Western countries. Treatment is complex and often requires surgical intervention. Extracorporeal shock wave lithotripsy is a relatively recent technique, widely used in the treatment of stones in the gallbladder and common bile duct. It can also be used in the treatment of intrahepatic stones. The present study analyses the efficacy of extracorporeal shock wave lithotripsy in intrahepatic stones. PATIENTS AND METHODS: In our study, we used extracorporeal lithotripsy in six cases of intrahepatic stones (mean age 53 years). In five of these cases deformities of the intrahepatic bile ducts were also present: stenoses and angulated strictures. The stones were in the right lobe of the liver in 5 patients, and in both lobes in 1 patient. Four patients had multiple stones and 2 a single stone, all varying in diameter from 6 to 25 mm. The stones were localized radiologically with contrast medium through a drainage tube. The technique does not require anaesthesia. An average of three lithotripsy sessions were necessary, with a mean total of 8050 shock waves per patient. RESULTS: Successful fragmentation was obtained in 5 out of 6 patients, while the remaining subsequently underwent surgery. No complications were observed. CONCLUSIONS: Extracorporeal shock wave lithotripsy proved to be effective, easy to perform and safe for the treatment of intrahepatic stones.

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• Low day 3 luteinizing hormone values are predictive of reduced response to ovarian stimulation

  Human Reproduction · 1998-03-01 · 43 citations

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  The aim of the present work was to evaluate whether low day 3 luteinizing hormone (LH) values in the presence of normal follicle stimulating hormone (FSH) are predictive of poor response to ovarian stimulation. Two groups of women undergoing ovarian stimulation and differing only in the day 3 LH concentration (<3 mIU/ml, study group, n=30; >3 mIU/ml, control group, n=45) were retrospectively analysed. Study group patients developed a lower oestradiol peak (703+/-388 versus 955+/-400 ng/ml; P = 0.005) and a lower number of follicles >15 mm diameter at the time of human chorionic gonadotrophin (HCG) administration (2.6+/-1.3 versus 3.6+/-1.8; P=0.004) than the control group. Conversely, a similar ratio of oestradiol: follicles >15 mm diameter was observed (256+/-118 versus 269+/-93; P=0.563). The number of follicles >10 mm at the time of HCG administration appeared to be lower in the study group, but this difference was not statistically significant (6+/-3.9 versus 7.8+/-4.3). Our data indicate that day 3 LH values <3 mIU/ml are predictive of poor response to ovarian stimulation.

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• [The echographic and clinical follow-up of patients operated on for subcutaneous rupture of the Achilles tendon].

  PubMed · 1996-06-06 · 6 citations

  article1st authorCorresponding

  Thanks to its good long-term results, surgery is the method of choice to treat subcutaneous ruptures of the Achilles tendon. Reconstructed tendons present typical morphological and functional US patterns which depend partly on the kind of surgical reconstruction and partly on the time passed since surgery. The authors report the results of the clinical and US follow-up of a series of 62 surgical patients treated in 7 years for the subcutaneous rupture of the Achilles tendon. The patients were 55 men and 7 women, whose mean age was 36 years (range: 25-65 years). The left-hand side was affected in 38 patients and the right-hand side in 24 patients. All patients were operated on using an end-to-end suture and reinforcement plastic surgery pulling down a gastrocnemius tendon flap. To homogenize the results, all the US exams were performed by the same operator, in the presence of the orthopedic specialist and under the same conditions: both the involved and the contralateral Achilles tendons were studied, longitudinal and transverse scans were performed with the foot in max. plantar and dorsal flexion and, whenever possible, dynamic scans were also performed making the sural triceps contract against resistance. The following parameters were studied clinically: pain (which was absent in 39 patients, occasional in 11, after stress in 9 and on walking in 3 patients), skin scar trophism (which was eutrophic in 53.23% of patients, keloid in 27.42% and hypertrophic in 19.35% of patients), ankle joint excursion (plantar flexion was impaired in 32.3% and dorsal flexion in 36% of patients), walking on tiptoe (in all, 22.6% of patients complained of difficulties walking on tiptoe) and, finally, work activity resumption (which all patients achieved). US depicted the surgical tendons as much bigger than the contralateral ones (3-4 times on the average), which increase in volume lasted throughout the follow-up. In 75% of patients the echo structure of the surgical tendons was inhomogeneous, with scattered hypoechoic and hyperechoic areas. In the extant 25% of patients, nearly all of them followed-up for over 6 years, US depicted a clear-cut hyperechoic area whose size and echo structure were similar to the healthy tendons'. Our results strongly suggest that tenorrhaphy and flap plastic surgery be used to repair subcutaneous ruptures of the Achilles tendon. US proved to be the most reliable and feasible method also in the follow-up. The US images of the patients submitted to surgery more than 6 years earlier revealed fibrillate reorganization patterns and tendon restructuring. These processes involve both ends of the sutured tendon and not the reinforcement flap, which further confirms the exclusively mechanical, and not biological, function of the latter.

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• [Diagnostic impact of ultrasonography in abdominal diseases].

  PubMed · 1996-05-01

  article1st authorCorresponding

  The diagnostic accuracy of conventional radiography and ultrasound (US) in patients with acute or chronic abdominal pain was investigated by the authors in two prospective studies to assess the capabilities of the two imaging techniques. 262 patients (135 men and 127 women, age range: 25-83 years) were entered into the study within 8 months. The patients were divided into different groups according to clinical presentation (80 patients with acute and 182 with chronic pain) and to the referring physician (a hospital clinician for 127 patients and a general practitioner for 135 patients). For each technique the presence (positive result) or the absence (negative result) of abnormal imaging features related to clinical symptoms was recorded and the agreement of conventional radiography and US findings was assessed. Statistical analysis showed similar sensitivity of conventional radiography and US in the examination of acute hospitalized patients (54.3% positive results), chronic hospitalized patients (28.1% negative results) and chronic nonhospitalized patients (47.2% negative results). The results of our prospective studies showed poor diagnostic accuracy of the two techniques and clearly evidenced the improper use of diagnostic imaging methods by referring physicians, with a technical-oriented attitude in imaging examination requests. In the authors' opinion, a clinical-based approach by referring physicians with accurate patient selection might improve diagnostic accuracy, the cost/benefit ratio and the clinical effectiveness of imaging techniques.

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• Clinical and ultrasound follow-up of 62 patients submitted to the surgical treatment of subcutaneous rupture of the Achilles tendon.

  PubMed · 1994-12-21 · 3 citations

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  A total of 62 patients submitted to the surgical treatment of subcutaneous rupture of the Achilles tendon were followed up after a period of time ranging from 2 to 8 years. End-to-end suturing and reinforcement plastic surgery obtained excellent clinical results in more than 80% of the cases, with complications which were principally inherent to scarring. There were no cases of rupture. In cases with a longer follow-up, ultrasound examination revealed aspects of fibrillate restructuring of the tendon.

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• [Homogenized thoracic radiography].

  PubMed · 1994-10-01

  article1st authorCorresponding

  The major obstacle to optimal radiographic depiction of the chest has always been its anatomical features and, in particular, the considerable difference in X-ray beam attenuation between pulmonary and mediastinal structures. At least 40% of this region cannot be visualized in an optimal way. Therefore, much technological work was done to overcome this limitation, which has recently led to the development of electronic (Amber) and mechanical (homogenization) filtration systems. This study was aimed at assessing the capabilities of mechanical filtration, in terms of anatomical representation and lower biologic cost, the latter intended as lower exposure and absorbed doses. Therefore, eight radiologists studied 40 negative radiographs, i.e., a homogenized radiograph and a non-homogenized one per patient, twenty patients in all. The statistical analysis of the radiographs demonstrated the homogenized technique to allow better visualization of all the anatomical structures examined, i.e., trachea, carina, right and left main bronchi, aorta, spine and retrocardiac region. In contrast, the two radiographic techniques yielded much the same results in the depiction of the pulmonary pattern. As for dosimetry, good results were also obtained, because the homogenizer made it possible to reduce both exposure and absorbed doses to the lung and thyroid, while in the mediastinal region the absorbed dose remained similar to that measured with the non-homogenized even though exposure dose was increased mildly.

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• Distinct patterns of spatial frequency response by normal, recovered optic neuritis, and normal fellow eyes to a new linearly variable neutral density device

  Graefe s Archive for Clinical and Experimental Ophthalmology · 1993-02-01 · 2 citations

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• [A volumetric increase in the submandibular glands due to an organic iodate contrast medium. A case report].

  PubMed · 1993-05-25

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• [Ultrasonographic semiology of biliary prostheses].

  PubMed · 1993-11-01

  article1st authorCorresponding

  US was used to study 60 patients with different types of plastic (Home-made, Lunderquist, Miller, Carey-Coons, Lammer) and metallic (Z-stent, Wallstent) biliary stents, from October 1990 to March 1993. The optimal US approach was assessed, together with several US features which are typical of each type of endoprosthesis. As far as plastic endoprostheses are concerned, independent of manufacturing differences, the typical US pattern on longitudinal scans is a hyperechoic double line while, on transverse scans, the prosthesis cylinder is represented by short hyperechoic lines, resembling the mathematic equal sign. According to the different types, metallic stents appear as thin hyperechoic lines or narrow gratings on longitudinal scans and as hyperechoic spots following a circular pattern or as a hyperechoic ring on transverse scans.

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Frequent coauthors

• Barry A. Maltzman

  Hudson Dermatology

  18 shared

• Donald J. Cinotti

  Rutgers New Jersey Medical School

  14 shared

• William H. Constad

  14 shared

• Paolo Mannella

  11 shared

• Philip M. Fiore

  Harvard University

  10 shared

• George Stephens

  University of Tennessee at Knoxville

  7 shared

• Anthony Caputo

  7 shared

• John H. White

  6 shared

Education

• M.D.

  State University of New York at Brooklyn

  1946